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Modern data analysis pipelines are becoming increasingly complex due to the presence of multi-view information sources. While graphs are effective in modeling complex relationships, in many scenarios a single graph is rarely sufficient to…

Machine Learning · Statistics 2019-04-02 Uday Shankar Shanthamallu , Jayaraman J. Thiagarajan , Huan Song , Andreas Spanias

Quantitative genetic studies that model complex, multivariate phenotypes are important for both evolutionary prediction and artificial selection. For example, changes in gene expression can provide insight into developmental and…

Applications · Statistics 2013-05-03 Daniel E Runcie , Sayan Mukherjee

Background: In recent years, researchers have made significant strides in understanding the heterogeneity of breast cancer and its various subtypes. However, the wealth of genomic and proteomic data available today necessitates efficient…

Quantitative Methods · Quantitative Biology 2024-03-04 Leandro Y. S. Okimoto , Rayol Mendonca-Neto , Fabíola G. Nakamura , Eduardo F. Nakamura , David Fenyö , Claudio T. Silva

It has been rightfully emphasized that the use of AI for clinical decision making could amplify health disparities. An algorithm may encode protected characteristics, and then use this information for making predictions due to undesirable…

Machine Learning · Computer Science 2022-07-22 Ben Glocker , Charles Jones , Melanie Bernhardt , Stefan Winzeck

As artificial intelligence methods are increasingly applied to complex task scenarios, high dimensional multi-label learning has emerged as a prominent research focus. At present, the curse of dimensionality remains one of the major…

Machine Learning · Computer Science 2025-04-18 Yifan Cao , Zhilong Mi , Ziqiao Yin , Binghui Guo , Jin Dong

Sparse Neural Networks (SNNs) have emerged as powerful tools for efficient feature selection. Leveraging the dynamic sparse training (DST) algorithms within SNNs has demonstrated promising feature selection capabilities while drastically…

Multi-model inference covers a wide range of modern statistical applications such as variable selection, model confidence set, model averaging and variable importance. The performance of multi-model inference depends on the availability of…

Statistics Theory · Mathematics 2019-06-07 Ching-Wei Cheng , Guang Cheng

Feature selection is a core area of data mining with a recent innovation of graph-driven unsupervised feature selection for linked data. In this setting we have a dataset $\mathbf{Y}$ consisting of $n$ instances each with $m$ features and a…

Machine Learning · Computer Science 2020-07-07 Zilong Bai , Hoa Nguyen , Ian Davidson

Feature Selection (FS) has become the focus of much research on decision support systems areas for which data sets with tremendous number of variables are analyzed. In this paper we present a new method for the diagnosis of Coronary Artery…

Machine Learning · Computer Science 2013-05-28 Sidahmed Mokeddem , Baghdad Atmani , Mostefa Mokaddem

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

Feature selection plays an important role in the data mining process. It is needed to deal with the excessive number of features, which can become a computational burden on the learning algorithms. It is also necessary, even when…

Machine Learning · Computer Science 2015-10-13 Tarek Amr Abdallah , Beatriz de La Iglesia

Literature on machine learning for multiple sclerosis has primarily focused on the use of neuroimaging data such as magnetic resonance imaging and clinical laboratory tests for disease identification. However, studies have shown that these…

Feature selection is one of the most challenging issues in machine learning, especially while working with high dimensional data. In this paper, we address the problem of feature selection and propose a new approach called Evolving Fast and…

Neural and Evolutionary Computing · Computer Science 2020-05-12 Uzay Cetin , Yunus Emre Gundogmus

Gene regulatory networks (GRNs) represent the causal relationships between transcription factors (TFs) and target genes in single-cell RNA sequencing (scRNA-seq) data. Understanding these networks is crucial for uncovering disease…

Artificial Intelligence · Computer Science 2024-10-22 Tejumade Afonja , Ivaxi Sheth , Ruta Binkyte , Waqar Hanif , Thomas Ulas , Matthias Becker , Mario Fritz

The application of machine learning to transcriptomics data has led to significant advances in cancer research. However, the high dimensionality and complexity of RNA sequencing (RNA-seq) data pose significant challenges in pan-cancer…

Genomics · Quantitative Biology 2024-08-15 Jong Hyun Kim , Jongseong Jang

Biological systems are driven by intricate interactions among the complex array of molecules that comprise the cell. Many methods have been developed to reconstruct network models of those interactions. These methods often draw on large…

Molecular Networks · Quantitative Biology 2018-06-29 Marieke Lydia Kuijjer , Matthew Tung , GuoCheng Yuan , John Quackenbush , Kimberly Glass

Traditionally, signal classification is a process in which previous knowledge of the signals is needed. Human experts decide which features are extracted from the signals, and used as inputs to the classification system. This requirement…

Neural and Evolutionary Computing · Computer Science 2019-04-11 Daniel Rivero , Enrique Fernandez-Blanco , Julian Dorado , Alejandro Pazos

Many datasets include a small set of variables, such as biomarkers or clinical outcomes, whose relationships to the broader system are of primary scientific interest. Estimating the full network of inter-variable relationships in such…

Methodology · Statistics 2026-05-14 Omar Melikechi , David B. Dunson , Noureddine Melikechi , Jeffrey W. Miller

In recent years the importance of finding a meaningful pattern from huge datasets has become more challenging. Data miners try to adopt innovative methods to face this problem by applying feature selection methods. In this paper we propose…

Machine Learning · Computer Science 2014-03-11 Mehdi Naseriparsa , Amir-masoud Bidgoli , Touraj Varaee

High-dimensional feature selection is a central problem in a variety of application domains such as machine learning, image analysis, and genomics. In this paper, we propose graph-based tests as a useful basis for feature selection. We…

Methodology · Statistics 2024-08-13 Swarnadip Ghosh , Somabha Mukherjee , Divyansh Agarwal , Yichen He , Mingzhi Song , Xuejiao Pei
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