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We study the problem of performing automated experiment design for drug screening through Bayesian inference and optimisation. In particular, we compare and contrast the behaviour of linear-Gaussian models and Gaussian processes, when used…

Machine Learning · Computer Science 2021-05-11 Hannes Eriksson , Christos Dimitrakakis , Lars Carlsson

Tree-structured data naturally appear in various fields, particularly in biology where plants and blood vessels may be described by trees, but also in computer science because XML documents form a tree structure. This paper is devoted to…

Statistics Theory · Mathematics 2019-04-09 Romain Azaïs , Alexandre Genadot , Benoît Henry

Ensembles of decision trees are a useful tool for obtaining for obtaining flexible estimates of regression functions. Examples of these methods include gradient boosted decision trees, random forests, and Bayesian CART. Two potential…

Methodology · Statistics 2018-09-18 Antonio Ricardo Linero , Yun Yang

Gaussian Processes are widely used for regression tasks. A known limitation in the application of Gaussian Processes to regression tasks is that the computation of the solution requires performing a matrix inversion. The solution also…

Machine Learning · Computer Science 2017-08-22 Sourish Das , Sasanka Roy , Rajiv Sambasivan

We derive an upper bound for the efficiency of estimating entries in the inverse covariance matrix of a high dimensional distribution. We show that in order to approximate an off-diagonal entry of the density matrix of a $d$-dimensional…

Statistics Theory · Mathematics 2015-05-06 Ronen Eldan

Our concern is selecting the concentration matrix's nonzero coefficients for a sparse Gaussian graphical model in a high-dimensional setting. This corresponds to estimating the graph of conditional dependencies between the variables. We…

Methodology · Statistics 2010-04-05 Christophe Ambroise , Julien Chiquet , Catherine Matias

We present a consistent and highly scalable local approach to learn the causal structure of a linear Gaussian polytree using data from interventional experiments with known intervention targets. Our methods first learn the skeleton of the…

Machine Learning · Statistics 2023-11-09 D. Tramontano , L. Waldmann , M. Drton , E. Duarte

This paper considers the problem of regression analysis with random covariance matrix as outcome and Euclidean covariates in the framework of Fr\'echet regression on the Bures-Wasserstein manifold. Such regression problems have many…

Methodology · Statistics 2024-09-17 Haoshu Xu , Hongzhe Li

Phylogenetics is now fundamental in life sciences, providing insights into the earliest branches of life and the origins and spread of epidemics. However, finding suitable phylogenies from the vast space of possible trees remains…

Populations and Evolution · Quantitative Biology 2024-01-24 Matthew J Penn , Neil Scheidwasser , Joseph Penn , Christl A Donnelly , David A Duchêne , Samir Bhatt

Motivated by statistical inference problems in high-dimensional time series data analysis, we first derive non-asymptotic error bounds for Gaussian approximations of sums of high-dimensional dependent random vectors on hyper-rectangles,…

Statistics Theory · Mathematics 2024-06-05 Jinyuan Chang , Xiaohui Chen , Mingcong Wu

Gaussian graphical models (GGMs) are well-established tools for probabilistic exploration of dependence structures using precision matrices. We develop a Bayesian method to incorporate covariate information in this GGMs setup in a nonlinear…

Understanding the impact of data structure on the computational tractability of learning is a key challenge for the theory of neural networks. Many theoretical works do not explicitly model training data, or assume that inputs are drawn…

Machine Learning · Statistics 2022-05-23 Sebastian Goldt , Bruno Loureiro , Galen Reeves , Florent Krzakala , Marc Mézard , Lenka Zdeborová

The power spectrum of weak lensing fluctuations has a non-Gaussian distribution due to its quadratic nature. On small scales the Central Limit Theorem acts to Gaussianize this distribution but non-Gaussianity in the signal due to…

Cosmology and Nongalactic Astrophysics · Physics 2022-06-29 Alex Hall , Andy Taylor

Using the linear Gaussian latent variable model as a starting point we relax some of the constraints it imposes by deriving a nonparametric latent feature Gaussian variable model. This model introduces additional discrete latent variables…

Machine Learning · Statistics 2019-05-28 Adam Farooq , Yordan P. Raykov , Luc Evers , Max A. Little

We consider the problem of jointly estimating multiple related zero-mean Gaussian distributions from data. We propose to jointly estimate these covariance matrices using Laplacian regularized stratified model fitting, which includes loss…

Machine Learning · Statistics 2020-05-25 Jonathan Tuck , Stephen Boyd

Machine learning models used in medical applications often face challenges due to the covariate shift, which occurs when there are discrepancies between the distributions of training and target data. This can lead to decreased predictive…

Machine Learning · Computer Science 2024-12-24 Mingyang Cai , Thomas Klausch , Mark A. van de Wiel

This is the first in a series of two works which study the discrete Gaussian free field on the binary tree when all leaves are conditioned to be positive. In this work, we obtain sharp asymptotics for the probability of this "hard-wall…

Probability · Mathematics 2024-09-04 Maximilian Fels , Lisa Hartung , Oren Louidor

We investigate whether a Gaussian likelihood is sufficient to obtain accurate parameter constraints from a Euclid-like combined tomographic power spectrum analysis of weak lensing, galaxy clustering and their cross-correlation. Testing its…

Cosmology and Nongalactic Astrophysics · Physics 2021-03-03 Robin E. Upham , Michael L. Brown , Lee Whittaker

In this paper we investigate the geometry of a discrete Bayesian network whose graph is a tree all of whose variables are binary and the only observed variables are those labeling its leaves. We provide the full geometric description of…

Statistics Theory · Mathematics 2011-10-20 Piotr Zwiernik , Jim Q. Smith

Understanding the temporal evolution of sets of vectors is a fundamental challenge across various domains, including ecology, crime analysis, and linguistics. For instance, ecosystem structures evolve due to interactions among plants,…

Machine Learning · Computer Science 2025-12-18 Taichi Aida , Mamoru Komachi , Toshinobu Ogiso , Hiroya Takamura , Daichi Mochihashi
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