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Modern ecology has re-emphasized the need for a quantitative understanding of the original 'survival of the fittest theme' based on analyzis of the intricate trade-offs between competing evolutionary strategies that characterize the…

Populations and Evolution · Quantitative Biology 2015-06-16 Jacopo Grilli , Samir Suweis , Amos Maritan

Cells often have tens of thousands of receptors, even though only a few activated receptors can trigger full cellular responses. Reasons for the overabundance of receptors remain unclear. We suggest that, in certain conditions, the large…

Molecular Networks · Quantitative Biology 2014-02-04 Xiang Cheng , Lina Merchan , Martin Tchernookov , Ilya Nemenman

The origin of heredity is studied as a recursive state in a replicating proto-cell consisting of many molecule species in mutually catalyzing reaction networks. Protocells divide when the number of molecules, increasing due to replication,…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Kunihiko Kaneko

Sexual reproduction in Nature requires two sexes, which raises the question why the reproductive scheme did not evolve to have three or more sexes. Here we construct a constrained optimization model based on the communication theory to…

Populations and Evolution · Quantitative Biology 2007-05-23 Bo Deng

Cellular heterogeneity is an immanent property of biological systems that covers very different aspects of life ranging from genetic diversity to cell-to-cell variability driven by stochastic molecular interactions, and noise induced cell…

Quantitative Methods · Quantitative Biology 2021-09-15 Niko Komin , Alexander Skupin

Microbes require several complex organic molecules for growth. A species may obtain a required factor by taking up molecules released by other species or by synthesizing the molecule. The patterns of uptake and synthesis set a flow of…

Populations and Evolution · Quantitative Biology 2014-02-27 Steven A. Frank

Evolving biomolecular networks have to combine the stability against perturbations with flexibility allowing their constituents to assume new roles in the cell. Gene duplication followed by functional divergence of associated proteins is a…

Molecular Networks · Quantitative Biology 2007-05-23 Sergei Maslov , Kim Sneppen , Kasper Astrup Eriksen

Diversity is a fundamental feature of ecosystems, even when the concept of ecosystem is extended to sociology or economics. Diversity can be intended as the count of different items, animals, or, more generally, interactions. There are two…

Physics and Society · Physics 2016-09-14 Andrea Tacchella , Riccardo Di Clemente , Andrea Gabrielli , Luciano Pietronero

Understanding the emergence and evolution of multicellularity and cellular differentiation is a core problem in biology. We develop a quantitative model that shows that a multicellular form emerges from genetically identical unicellular…

Populations and Evolution · Quantitative Biology 2017-02-07 Iaroslav Ispolatov , Martin Ackermann , Michael Doebeli

Eukaryote genomes contain excessively introns, inter-genic and other non-genic sequences that appear to have no vital functional role or phenotype manifestation. Their existence, a long-standing puzzle, is viewed from the principle of…

Populations and Evolution · Quantitative Biology 2008-07-08 Salla Jaakkola , Sedeer El-Showk , Arto Annila

Commonly recognized evolutionarily relevant effects of sexual reproduction include increased diversity, accelerated adaptation, and constrained accumulation of deleterious mutations, along with a secondary effect of species genotype…

Populations and Evolution · Quantitative Biology 2025-06-17 Assaf Marron , Smadar Szekely , Irun R. Cohen , David Harel

As few real systems comprise indistinguishable units, diversity is a hallmark of nature. Diversity among interacting units shapes properties of collective behavior such as synchronization and information transmission. However, the benefits…

Neurons and Cognition · Quantitative Biology 2016-05-06 Leonardo L. Gollo , Mauro Copelli , James A. Roberts

Adaptive control in biological systems, such as intestinal immunity, remains poorly understood despite detailed knowledge of underlying regulatory networks. We propose an alternative framework based on stochastic martingale turnover, in…

Adaptation and Self-Organizing Systems · Physics 2026-05-01 Tomoyuki Yamaguchi

Direct reciprocity is a powerful mechanism for evolution of cooperation based on repeated interactions between the same individuals. But high levels of cooperation evolve only if the benefit-to-cost ratio exceeds a certain threshold that…

Populations and Evolution · Quantitative Biology 2023-05-31 Josef Tkadlec , Christian Hilbe , Martin A. Nowak

Cells are able to generate phenotypic diversity both during development and in response to stressful and changing environments, aiding survival. The biologically and medically vital process of a cell assuming a functionally important fate…

Cell Behavior · Quantitative Biology 2019-12-16 Ryan Kerr , Sara Jabbari , Iain G. Johnston

Species coexistence is one of the central themes in modern ecology. Coexistence is a prerequisite of biological diversity. However, the question arises how biodiversity can be reconciled with the statement of competition theory, which…

Populations and Evolution · Quantitative Biology 2007-08-17 Dalius Balciunas

Basic problems for the construction of a scenario for the Life are discussed. To study the problems in terms of dynamical systems theory, a scheme of intra-inter dynamics is presented. It consists of internal dynamics of a unit, interaction…

adap-org · Physics 2015-06-24 Kunihiko Kaneko

There are both benefits and drawbacks to cultural diversity. It can lead to friction and exacerbate differences. However, as with biological diversity, cultural diversity is valuable in times of upheaval; if a previously effective solution…

Neurons and Cognition · Quantitative Biology 2019-07-19 Liane Gabora , Stefan Leijnen

The interplay between energy efficiency and evolutionary mechanisms is addressed. One important question is how evolutionary mechanisms can select for the optimised usage of energy in situations where it does not lead to immediate…

Populations and Evolution · Quantitative Biology 2016-11-21 André Amado , Lenin Fernández , Weini Huang , Fernando F. Ferreira , Paulo R. A. Campos

Explaining biodiversity is a central focus in theoretical ecology. A significant obstacle arises from the Competitive Exclusion Principle (CEP), which states that two species competing for the same type of resources cannot coexist at…

Populations and Evolution · Quantitative Biology 2025-06-18 Ju Kang , Yiyuan Niu , Xin Wang