Related papers: A Conversation with Robert C. Elston
Beginning in the 1970s, Alexander Philip Dawid has been a leading contributor to the foundations of statistics and especially to the development and application of Bayesian statistics. He is also known for his work on causality, especially…
Pranab Kumar Sen was born on November 7, 1937 in Calcutta, India. His father died when Pranab was 10 years old, so his mother raised the family of seven children. Given his superior performance on an exam, Pranab nearly went into medical…
Recent work has attempted to use whole-genome sequence data from pathogens to reconstruct the transmission trees linking infectors and infectees in outbreaks. However, transmission trees from one outbreak do not generalize to future…
The Committee of Presidents of Statistical Societies (COPSS) will celebrate its 50th Anniversary in 2013. As part of its celebration, COPSS intends to publish a book with contributions from the past recipients of its four awards, namely the…
The following conversation is based in part on a transcript of a 2009 interview funded by Pfizer Global Research-Connecticut, the American Statistical Association and the Department of Statistics at the University of Connecticut-Storrs as…
As the amount and complexity of genetic information increases it is necessary that we explore some efficient ways of handling these data. This study takes the "divide and conquer" approach for analyzing high dimensional genomic data. Our…
Studies about epidemic modelling have been conducted since before 19th century. Both deterministic and stochastiic model were used to capture the dynamic of infection in the population. The purpose of this project is to investigate the…
This paper summarizes and discusses the methodological research in human genetic linkage analysis, leading up to and following from the paper of C. A. B. Smith presented as a Royal Statistical Society discussion paper in 1953. This paper…
Yuan Shih Chow was born in Hubei province in China, on September 1, 1924. The eldest child of a local militia and political leader, he grew up in war and turmoil. His hometown was on the front line during most of the Japanese invasion and…
1.A goal of many research programs in biology is to extract meaningful insights from large, complex data sets. Researchers in Ecology, Evolution and Behavior (EEB) often grapple with long-term, observational data sets from which they…
These are notes for a set of 7 two-hour lectures given at the 2010 Summer School on Quantitative Evolutionary and Comparative Genomics at OIST, Okinawa, Japan. The emphasis is on understanding how biological systems process information. We…
There have been many studies to examine whether one trait is correlated with another trait across a group of present-day species (for example, do species with larger brains tend to have longer gestation times. Since the introduction of the…
Brucellosis is a zoonotic bacterial infectious disease that affects livestock and wildlife. The Greater Yellowstone Ecosystem is the last area in the United States where cattle are regularly infected with brucellosis. Even though livestock…
This paper proposes a novel evolutionary algorithm called Epistocracy which incorporates human socio-political behavior and intelligence to solve complex optimization problems. The inspiration of the Epistocracy algorithm originates from a…
This is the transcript of the after-dinner talk I gave at the close of the 16 Nov 2013 symposium "Celebrating the Science of Kenneth Geddes Wilson" [1] at Cornell University (see Fig. 1 for the poster). The video of my talk is on-line [2],…
Determining cell identities in imaging sequences is an important yet challenging task. The conventional method for cell identification is via cell tracking, which is complex and can be time-consuming. In this study, we propose an innovative…
An important problem in evolutionary genomics is to investigate whether a certain trait measured on each sample is associated with the sample phylogenetic tree. The phylogenetic tree represents the shared evolutionary history of the samples…
Reconstructing pathogen dynamics from genetic data as they become available during an outbreak or epidemic represents an important statistical scenario in which observations arrive sequentially in time and one is interested in performing…
These notes provide a short, focused introduction to modelling stochastic gene expression, including a derivation of the master equation, the recovery of deterministic dynamics, birth-and-death processes, and Langevin theory. The notes were…
The goal of these lectures is to review some mathematical aspects of random tree models used in evolutionary biology to model gene trees or species trees. We start with stochastic models of tree shapes (finite trees without edge lengths),…