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Mathematical models are essential tools to study how the cardiovascular system maintains homeostasis. The utility of such models is limited by the accuracy of their predictions, which can be determined by uncertainty quantification (UQ). A…

Quantitative Methods · Quantitative Biology 2018-07-20 Andrew D. Marquis , Andrea Arnold , Caron Dean , Brian E. Carlson , Mette S. Olufsen

Freight transportation modeling often struggles with data limitations, especially in accurately representing complex supplier selection processes and their impact on network flows. This research addresses this critical gap by developing a…

Optimization and Control · Mathematics 2026-05-07 Abdelrahman Ismael , Taner Cokyasar

This paper studies the control problem for safety-critical multi-agent systems based on quadratic programming (QP). Each controlled agent is modeled as a cascade connection of an integrator and an uncertain nonlinear actuation system. In…

Systems and Control · Electrical Eng. & Systems 2022-12-01 Si Wu , Tengfei Liu , Magnus Egerstedt , Zhong-Ping Jiang

Uncertainty quantification (UQ) is a vital step in using mathematical models and simulations to take decisions. The field of cardiac simulation has begun to explore and adopt UQ methods to characterise uncertainty in model inputs and how…

We propose a novel non-linear extension to the Orienteering Problem (OP), called the Correlated Orienteering Problem (COP). We use COP to model the planning of informative tours for the persistent monitoring of a spatiotemporal field with…

Robotics · Computer Science 2014-12-16 Jingjin Yu , Mac Schwager , Daniela Rus

We propose the use of the probability integral transform (PIT) for model validation in point process models. The simple PIT diagnostics assess the calibration of the model and can detect inconsistencies in both the intensity and the…

Methodology · Statistics 2013-05-16 Thordis L. Thorarinsdottir

Predicting the final folded structure of protein molecules and simulating their folding pathways is of crucial importance for designing viral drugs and studying diseases such as Alzheimer's at the molecular level. To this end, this paper…

Systems and Control · Electrical Eng. & Systems 2021-04-28 Alireza Mohammadi , Mark W. Spong

We consider traffic flow dynamics for a network of signalized intersections, where the outflow from every link is constrained to be equal to a given capacity function if the queue length is positive, and equal to the minimum of cumulative…

Dynamical Systems · Mathematics 2017-09-13 Pouyan Hosseini , Ketan Savla

Numerous studies have shown the effectiveness of intelligent transportation system techniques such as variable speed limit (VSL), lane change (LC) control, and ramp metering (RM) in freeway traffic flow control. The integration of these…

Systems and Control · Electrical Eng. & Systems 2025-05-12 Tianchen Yuan , Petros A. Ioannou

We introduce the Pointer Q-Network (PQN), a hybrid neural architecture that integrates model-free Q-value policy approximation with Pointer Networks (Ptr-Nets) to enhance the optimality of attention-based sequence generation, focusing on…

Machine Learning · Computer Science 2024-10-25 Alessandro Barro

Arterial traffic interacts with freeway traffic, yet the two are controlled independently. Arterial traffic signals do not take into account freeway traffic and how ramps control ingress traffic and have no control over egress traffic from…

Systems and Control · Electrical Eng. & Systems 2024-04-10 Tianchen Yuan , Petros A. Ioannou

In this paper, we study the problem of traffic management in highways facing stochastic perturbations. To model the macroscopic traffic flow under perturbations, we use cell-transmission model with Markovian capacities. The decision…

Systems and Control · Computer Science 2019-07-04 Li Jin , Alexander A. Kurzhanskiy , Saurabh Amin

Quantum annealing (QA) is a heuristic search algorithm that can run on Adiabatic Quantum Computation (AQC) processors to solve combinatorial optimization problems. Although theoretical studies and simulations on classic hardware have shown…

Pulmonary arterial hypertension (PAH) is a progressive cardiopulmonary disease that leads to increased pulmonary pressures, vascular remodeling, and eventual right ventricular (RV) failure. Pediatric PAH remains understudied due to limited…

In model predictive control (MPC) an optimization problem has to be solved at each time step, which in real-time applications makes it important to solve these optimization problems efficiently and to have good upper bounds on worst-case…

Optimization and Control · Mathematics 2020-04-13 Daniel Arnström , Daniel Axehill

Quantum devices require precisely calibrated analog signals, a process that is complex and time-consuming. Many calibration strategies exist, and all require careful analysis and tuning to optimize system availability. To enable rigorous…

A Monte Carlo algorithm is proposed to simulate ferromagnetic q-state Potts model for any real q>0. A single update is a random sequence of disordering and deterministic moves, one for each link of the lattice. A disordering move attributes…

Statistical Mechanics · Physics 2008-12-18 Ferdinando Gliozzi

METANET is a widely used second-order macroscopic traffic flow model for freeway networks, supporting applications across traffic simulation, ramp metering, and variable speed limit control. The predictive accuracy of any traffic model,…

Systems and Control · Electrical Eng. & Systems 2026-05-25 Monica Chan , Shreyaa Raghavan , Cathy Wu

This paper presents a novel quadratic programming (QP) approach for constrained control allocation that directly incorporates continuous-time actuator rate constraints without requiring slack variables. Over-actuated aircraft…

Optimization and Control · Mathematics 2025-07-24 Süleyman Özkurt , Adrian Grimm , Walter Fichter

Model-based quantum optimal control promises to solve a wide range of critical quantum technology problems within a single, flexible framework. The catch is that highly-accurate models are needed if the optimized controls are to meet the…

Quantum Physics · Physics 2023-04-25 Andy J. Goldschmidt , Frederic T. Chong
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