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Atrial fibrillation (AF) is a leading cause of morbidity and mortality. AF prevalence increases with age, which is attributed to pathophysiological changes that aid AF initiation and perpetuation. Current state-of-the-art models are only…

Tissues and Organs · Quantitative Biology 2015-10-05 Julie Eatock , Yen Ting Lin , Eugene T. Y. Chang , Tobias Galla , Richard H. Clayton

Atrial fibrillation (AF) is the most common cardiac arrhythmia in human beings, and is associated with significant morbidity and mortality. The current standard of care includes interventional catheter ablation in selected patients, but the…

Atrial fibrillation (AF) increases the risk of stroke by a factor of four to five and is the most common abnormal heart rhythm. The progression of AF with age, from short self-terminating episodes to persistence, varies between individuals…

Tissues and Organs · Quantitative Biology 2016-10-12 Kishan A. Manani , Kim Christensen , Nicholas S. Peters

Mathematical models of cardiac electrical excitation are increasingly complex, with multiscale models seeking to represent and bridge physiological behaviours across temporal and spatial scales. The increasing complexity of these models…

Tissues and Organs · Quantitative Biology 2016-12-13 Yen Ting Lin , Eugene TY Chang , Julie Eatock , Tobias Galla , Richard H Clayton

Atrial fibrillation (AF) is the most common form of arrhythmia with accelerated and irregular heart rate (HR), leading to both heart failure and stroke and being responsible for an increase in cardiovascular morbidity and mortality. In…

Fluid Dynamics · Physics 2018-06-26 Stefania Scarsoglio , Caterina Gallo , Luca Ridolfi

The mechanism of atrial fibrillation (AF) is poorly understood, resulting in disappointing success rates of ablative treatment. Different mechanisms defined largely by different atrial activation patterns have been proposed and, arguably,…

Tissues and Organs · Quantitative Biology 2020-01-27 Max Falkenberg , Andrew J. Ford , Anthony C. Li , Alberto Ciacci , Nicholas S. Peters , Kim Christensen

Atrial fibrillation (AF) is the most common arrhythmia affecting millions of people in the Western countries and, due to the widespread impact on the population and its medical relevance, is largely investigated in both clinical and…

Medical Physics · Physics 2014-09-12 Stefania Scarsoglio , Andrea Guala , Carlo Camporeale , Luca Ridolfi

Thyrotoxicosis (TT) is associated with an increase in both total and cardiovascu-lar mortality. One of the main thyrotoxicosis risks is Atrial Fibrillation (AF). Right AF predicts help medical personal prescribe the correct medicaments and…

Applications · Statistics 2020-03-02 Ilya V. Derevitskii , Daria A. Savitskaya , Alina Y. Babenko , Sergey V. Kovalchuk

Atrial Fibrillation (AF) is the most common type of arrhythmia (Greek a-, loss + rhythmos, rhythm = loss of rhythm) leading to hospitalization in the United States. Though sometimes AF is asymptomatic, it increases the risk of stroke and…

Machine Learning · Computer Science 2021-09-22 Samayan Bhattacharya , Sk Shahnawaz

Atrial fibrillation (AF) is characterized by irregular electrical impulses originating in the atria, which can lead to severe complications and even death. Due to the intermittent nature of the AF, early and timely monitoring of AF is…

Sound · Computer Science 2024-10-29 Xuanyu Liu , Jiao Li , Haoxian Liu , Zongqi Yang , Yi Huang , Jin Zhang

Atrial fibrillation (AF) is the most common cardiac arrhytmia, characterised by the chaotic motion of electrical wavefronts in the atria. In clinical practice, AF is classified under two primary categories: paroxysmal AF, short intermittent…

Tissues and Organs · Quantitative Biology 2020-07-01 Alberto Ciacci , Max Falkenberg , Kishan A. Manani , Tim S. Evans , Nicholas S. Peters , Kim Christensen

Catheter ablation of Atrial Fibrillation (AF) consists of a one-size-fits-all treatment with limited success in persistent AF. This may be due to our inability to map the dynamics of AF with the limited resolution and coverage provided by…

Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by rapid and irregular contractions of the atria. It significantly elevates the risk of strokes due to slowed blood flow in the atria, especially in the left atrial…

Machine Learning · Computer Science 2024-01-19 Tian Xie

Atrial fibrillation is a heart rhythm disorder that affects tens of millions people worldwide. The most effective treatment is catheter ablation. This involves irreversible heating of abnormal cardiac tissue facilitated by electroanatomical…

Medical Physics · Physics 2022-11-01 Jiyue He , Arkady Pertsov , Sanjay Dixit , Katie Walsh , Eric Toolan , Rahul Mangharam

Normal human heart rate shows complex fluctuations in time, which is natural, since heart rate is controlled by a large number of different feedback control loops. These unpredictable fluctuations have been shown to display fractal…

Medical Physics · Physics 2009-11-07 Tom A. Kuusela , Tony Shepherd , Jarmo Hietarinta

This review focuses on the computerized modeling of the electrophysiology of the human atria, emphasizing the simulation of common arrhythmias such as atrial flutter (AFlut) and atrial fibrillation (AFib). Which components of the model are…

Computational Physics · Physics 2025-05-30 Olaf Dössel , Axel Loewe

Atrial fibrillation (AF) is the most common arrhythmia, increasing the risk of stroke, heart failure, and other cardiovascular complications. While AF detection algorithms perform well in identifying persistent AF, early-stage progression,…

Machine Learning · Computer Science 2025-08-28 Yongbin Lee , Ki H. Chon

Atrial fibrillation (AF) is characterized by irregular electrical impulses originating in the atria, which can lead to severe complications and even death. Due to the intermittent nature of the AF, early and timely monitoring of AF is…

Sound · Computer Science 2024-08-12 Xuanyu Liu , Haoxian Liu , Jiao Li , Zongqi Yang , Yi Huang , Jin Zhang

One of the challenges in the development of patient-specific models of cardiac arrhythmias for clinical applications has been accounting for myocardial fiber organization. The fiber varies significantly from heart to heart, but cannot be…

Medical Physics · Physics 2023-07-22 Jiyue He , Arkady Pertsov , John Bullinga , Rahul Mangharam

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…

Medical Physics · Physics 2019-04-17 Stefania Scarsoglio , Caterina Gallo , Andrea Saglietto , Luca Ridolfi , Matteo Anselmino
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