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When gene copies are sampled from various species, the resulting gene tree might disagree with the containing species tree. The primary causes of gene tree and species tree discord include lineage sorting, horizontal gene transfer, and gene…

Populations and Evolution · Quantitative Biology 2010-03-08 Louxin Zhang

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

Populations and Evolution · Quantitative Biology 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

The reconstruction of a species phylogeny from genomic data faces two significant hurdles: 1) the trees describing the evolution of each individual gene--i.e., the gene trees--may differ from the species phylogeny and 2) the molecular…

Machine Learning · Computer Science 2017-07-17 Gautam Dasarathy , Elchanan Mossel , Robert Nowak , Sebastien Roch

Molecular phylogeny has focused mainly on improving models for the reconstruction of gene trees based on sequence alignments. Yet, most phylogeneticists seek to reveal the history of species. Although the histories of genes and species are…

Populations and Evolution · Quantitative Biology 2013-11-05 Gergely J. Szöllosi , Eric Tannier , Vincent Daubin , Bastien Boussau

Species tree estimation is a complex problem, due to the fact that different parts of the genome can have different evolutionary histories than the genome itself. One of the causes for this discord is incomplete lineage sorting (also called…

Populations and Evolution · Quantitative Biology 2019-04-09 Erin Molloy , Tandy Warnow

We consider the problem of estimating the evolutionary history of a set of species (phylogeny or species tree) from several genes. It is known that the evolutionary history of individual genes (gene trees) might be topologically distinct…

Populations and Evolution · Quantitative Biology 2016-11-18 Gautam Dasarathy , Robert Nowak , Sebastien Roch

We analyse a maximum-likelihood approach for combining phylogenetic trees into a larger `supertree'. This is based on a simple exponential model of phylogenetic error, which ensures that ML supertrees have a simple combinatorial description…

Populations and Evolution · Quantitative Biology 2007-08-17 Mike Steel , Allen Rodrigo

Phylogenetic networks model reticulate evolutionary histories. The last two decades have seen an increased interest in establishing mathematical results and developing computational methods for inferring and analyzing these networks. A…

Populations and Evolution · Quantitative Biology 2016-06-24 Jiafan Zhu , Yun Yu , Luay Nakhleh

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

A major problem for inferring species trees from gene trees is that evolutionary processes can sometimes favour gene tree topologies that conflict with an underlying species tree. In the case of incomplete lineage sorting, this phenomenon…

Populations and Evolution · Quantitative Biology 2012-12-03 Mike Steel , Simone Linz , Daniel H. Huson , Michael J. Sanderson

Gene trees are evolutionary trees representing the ancestry of genes sampled from multiple populations. Species trees represent populations of individuals -- each with many genes -- splitting into new populations or species. The coalescent…

Populations and Evolution · Quantitative Biology 2010-07-30 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

The inference of the evolutionary history of a collection of organisms is a problem of fundamental importance in evolutionary biology. The abundance of DNA sequence data arising from genome sequencing projects has led to significant…

Populations and Evolution · Quantitative Biology 2015-07-07 Julia Chifman , Laura Kubatko

Genomes and genes diversify during evolution; however, it is unclear to what extent genes still retain the relationship among species. Model species for molecular phylogenetic studies include yeasts and viruses whose genomes were sequenced…

Genomics · Quantitative Biology 2008-06-09 Yunfeng Shan , Xiu-Qing Li

One approach to estimating a species tree from a collection of gene trees is to first estimate probabilities of clades from the gene trees, and then to construct the species tree from the estimated clade probabilities. While a greedy…

Populations and Evolution · Quantitative Biology 2012-11-14 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

Given natural limitations on the length DNA sequences, designing phylogenetic reconstruction methods which are reliable under limited information is a crucial endeavor. There have been two approaches to this problem: reconstructing partial…

Data Structures and Algorithms · Computer Science 2008-12-10 Radu Mihaescu , Cameron Hill , Satish Rao

A phylogenetic tree is an important way in Bioinformatics to find the evolutionary relationship among biological species. In this research, a proposed model is described for the estimation of a phylogenetic tree for a given set of data. To…

Populations and Evolution · Quantitative Biology 2025-09-03 S M Rafiuddin

Motivation: Millions of genes in the modern species belong to only thousands of `gene families'. A gene family includes instances of the same gene in different species (orthologs) and duplicate genes in the same species (paralogs). Genes…

Populations and Evolution · Quantitative Biology 2012-05-04 Yu Zheng , Taoyang Wu , Louxin Zhang

The supertree problem asking for a tree displaying a set of consistent input trees has been largely considered for the reconstruction of species trees. Here, we rather explore this framework for the sake of reconstructing a gene tree from a…

Data Structures and Algorithms · Computer Science 2016-10-25 Manuel Lafond , Cédric Chauve , Nadia El-Mabrouk , Aïda Ouangraoua

A method was developed for Bayesian inference of species phylogeny using the multi-species coalescent model. To improve the mixing properties of the Markov chain Monte Carlo (MCMC) algorithm that traverses the space of species trees, we…

Populations and Evolution · Quantitative Biology 2015-12-15 Bruce Rannala , Ziheng Yang

Reconciling gene trees with a species tree is a fundamental problem to understand the evolution of gene families. Many existing approaches reconcile each gene tree independently. However, it is well-known that the evolution of gene families…

Populations and Evolution · Quantitative Biology 2018-06-12 Riccardo Dondi , Manuel Lafond , Celine Scornavacca
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