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A key aim of systems biology is the reconstruction of molecular networks, however we do not yet have networks that integrate information from all datasets available for a particular clinical condition. This is in part due to the limited…

Motivation: Laboratory gene regulatory data for a species are sporadic. Despite the abundance of gene regulatory network algorithms that employ single data sets, few algorithms can combine the vast but disperse sources of data and extract…

Genomics · Quantitative Biology 2020-08-17 Mehrzad Saremi , Maryam Amirmazlaghani

We quantify the influence of the topology of a transcriptional regulatory network on its ability to process environmental signals. By posing the problem in terms of information theory, we may do this without specifying the function…

Molecular Networks · Quantitative Biology 2015-06-26 Etay Ziv , Ilya Nemenman , Chris H. Wiggins

Reconciling gene trees with a species tree is a fundamental problem to understand the evolution of gene families. Many existing approaches reconcile each gene tree independently. However, it is well-known that the evolution of gene families…

Populations and Evolution · Quantitative Biology 2018-06-12 Riccardo Dondi , Manuel Lafond , Celine Scornavacca

The GEneral Matrix Multiplication (GEMM) is one of the essential algorithms in scientific computing. Single-thread GEMM implementations are well-optimised with techniques like blocking and autotuning. However, due to the complexity of…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-15 Yufan Xia , Marco De La Pierre , Amanda S. Barnard , Giuseppe Maria Junior Barca

The evolution of the genome has led to very sophisticated and complex regulation. Because of the abundance of non-coding RNA (ncRNA) in the cell, different species will promiscuously associate with each other, suggesting collective dynamics…

Molecular Networks · Quantitative Biology 2018-05-16 J. M. Deutsch

Batched network coding is a low-complexity network coding solution to feedbackless multi-hop wireless packet network transmission with packet loss. The data to be transmitted is encoded into batches where each of which consists of a few…

Information Theory · Computer Science 2022-05-10 Jie Wang , Zhiyuan Jia , Hoover H. F. Yin , Shenghao Yang

Deep neural networks achieve remarkable performance in many computer vision tasks. Most state-of-the-art (SOTA) semantic segmentation and object detection approaches reuse neural network architectures designed for image classification as…

Computer Vision and Pattern Recognition · Computer Science 2020-04-10 Jiemin Fang , Yuzhu Sun , Kangjian Peng , Qian Zhang , Yuan Li , Wenyu Liu , Xinggang Wang

This work is a part of ICLR Reproducibility Challenge 2019, we try to reproduce the results in the conference submission PADAM: Closing The Generalization Gap of Adaptive Gradient Methods In Training Deep Neural Networks. Adaptive gradient…

Machine Learning · Computer Science 2019-01-29 Harshal Mittal , Kartikey Pandey , Yash Kant

Manifold learning techniques have become increasingly valuable as data continues to grow in size. By discovering a lower-dimensional representation (embedding) of the structure of a dataset, manifold learning algorithms can substantially…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Andrew Lensen , Mengjie Zhang , Bing Xue

Research aimed at scaling up neuroscience inspired learning algorithms for neural networks is accelerating. Recently, a key research area has been the study of energy-based learning algorithms such as predictive coding, due to their…

Machine Learning · Computer Science 2026-01-30 Luca Pinchetti , Simon Frieder , Thomas Lukasiewicz , Tommaso Salvatori

Network alignment generalizes and unifies several approaches for forming a matching or alignment between the vertices of two graphs. We study a mathematical programming framework for network alignment problem and a sparse variation of it…

Optimization and Control · Mathematics 2011-11-03 Mohsen Bayati , David F. Gleich , Amin Saberi , Ying Wang

Gene regulation is a dynamic process that underlies all aspects of human development, disease response, and other key biological processes. The reconstruction of temporal gene regulatory networks has conventionally relied on regression…

Quantitative Methods · Quantitative Biology 2024-10-04 Euxhen Hasanaj , Barnabás Póczos , Ziv Bar-Joseph

In this paper, we consider the ChannelComp framework, where multiple transmitters aim to compute a function of their values at a common receiver while using digital modulations over a multiple access channel. ChannelComp provides a general…

Signal Processing · Electrical Eng. & Systems 2025-02-14 Xiaojing Yan , Saeed Razavikia , Carlo Fischione

The alignment of biological networks has the potential to teach us as much about biology and disease as has sequence alignment. Sequence alignment can be optimally solved in polynomial time. In contrast, network alignment is $NP$-hard,…

Molecular Networks · Quantitative Biology 2016-07-12 Nil Mamano , Wayne Hayes

Conventional hyperparameter optimization methods are computationally intensive and hard to generalize to scenarios that require dynamically adapting hyperparameters, such as life-long learning. Here, we propose an online hyperparameter…

Machine Learning · Computer Science 2021-04-09 Daniel Jiwoong Im , Cristina Savin , Kyunghyun Cho

Neural networks require a large amount of annotated data to learn. Meta-learning algorithms propose a way to decrease the number of training samples to only a few. One of the most prominent optimization-based meta-learning algorithms is…

Machine Learning · Computer Science 2022-06-14 Kostiantyn Khabarlak

Networking data analytics is increasingly used for enhanced network visibility and controllability. We draw the similarities between the Software Defined Networking (SDN) architecture and the MapReduce programming model. Inspired by the…

Networking and Internet Architecture · Computer Science 2016-09-13 Haoyu Song , Jun Gong , Hongfei Chen

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

Dimension reduction techniques usually lose information in the sense that reconstructed data are not identical to the original data. However, we argue that it is possible to have reconstructed data identically distributed as the original…

Machine Learning · Statistics 2026-05-15 Xinwei Shen , Nicolai Meinshausen