English
Related papers

Related papers: High Performance Computing of Gene Regulatory Netw…

200 papers

Reconstructing gene regulatory networks from large-scale heterogeneous data is a key challenge in biology. In multi-omics data analysis, networks based on pairwise statistical association measures remain popular, as they are easy to build…

Methodology · Statistics 2025-06-11 Ekaterina Tomilina , Florence Jaffrézic , Gildas Mazo

Recent advancements in deep learning-based image compression are notable. However, prevalent schemes that employ a serial context-adaptive entropy model to enhance rate-distortion (R-D) performance are markedly slow. Furthermore, the…

Applications · Statistics 2024-03-25 Haisheng Fu , Feng Liang , Jie Liang , Zhenman Fang , Guohe Zhang , Jingning Han

Omics technologies enable unbiased investigation of biological systems through massively parallel sequence acquisition or molecular measurements, bringing the life sciences into the era of Big Data. A central challenge posed by such omics…

Molecular Networks · Quantitative Biology 2014-11-04 Xiaoxi Dong , Anatoly Yambartsev , Stephen Ramsey , Lina Thomas , Natalia Shulzhenko , Andrey Morgun

Optimizing Pandas programs is a challenging problem. Existing systems and compiler-based approaches offer reliability but are either heavyweight or support only a limited set of optimizations. Conversely, using LLMs in a per-program…

Software Engineering · Computer Science 2026-02-11 Avaljot Singh , Dushyant Bharadwaj , Stefanos Baziotis , Kaushik Varadharajan , Charith Mendis

Compressed sensing (CS) is a challenging problem in image processing due to reconstructing an almost complete image from a limited measurement. To achieve fast and accurate CS reconstruction, we synthesize the advantages of two well-known…

Computer Vision and Pattern Recognition · Computer Science 2020-11-17 Nanyu Li , Charles C. Zhou

We introduce OpenRAND, a C++17 library aimed at facilitating reproducible scientific research through the generation of statistically robust and yet replicable random numbers. OpenRAND accommodates single and multi-threaded applications on…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-01 Shihab Shahriar Khan , Bryce Palmer , Christopher Edelmaierd , Hasan Metin Aktulga

Packet classification is a core function in software-defined networks, and learning-based methods have recently shown significant throughput gains on large-scale rulesets. However, existing learning-based approaches struggle with…

Networking and Internet Architecture · Computer Science 2026-01-07 Zhengyu Liao , Shiyou Qian

Efficient execution of parameter sensitivity analysis (SA) is critical to allow for its routinely use. The pathology image processing application investigated in this work processes high-resolution whole-slide cancer tissue images from…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-01 Eduardo Scartezini , Willian Barreiros , Tahsin Kurc , Jun Kong , Alba C. M. A. Melo , Joel Saltz , George Teodoro

We present NetReduce, a novel RDMA-compatible in-network reduction architecture to accelerate distributed DNN training. Compared to existing designs, NetReduce maintains a reliable connection between end-hosts in the Ethernet and does not…

Networking and Internet Architecture · Computer Science 2020-09-22 Shuo Liu , Qiaoling Wang , Junyi Zhang , Qinliang Lin , Yao Liu , Meng Xu , Ray C. C. Chueng , Jianfei He

Microstrip-like antenna (MLA) which was developed nearly a decade ago, is a powerful radiating element. The primary challenge in designing a MLA is to provide an optimized matching network such that the overall input reflection is kept as…

Optimization and Control · Mathematics 2015-09-04 Jalil Rasekhi , Jalil Rashed Mohasel

Video anomaly detection (VAD) is a critical yet challenging task due to the complex and diverse nature of real-world scenarios. Previous methods typically rely on domain-specific training data and manual adjustments when applying to new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Zhiwei Yang , Chen Gao , Mike Zheng Shou

The problems of computational data processing involving regression, interpolation, reconstruction and imputation for multidimensional big datasets are becoming more important these days, because of the availability of data and their widely…

Methodology · Statistics 2017-03-22 Yuri K. Shestopaloff , Alexander Y. Shestopaloff

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

Graph Neural Networks (GNNs) have achieved tremendous success in graph representation learning. Unfortunately, current GNNs usually rely on loading the entire attributed graph into network for processing. This implicit assumption may not be…

Machine Learning · Computer Science 2022-02-15 Junfu Wang , Yunhong Wang , Zhen Yang , Liang Yang , Yuanfang Guo

Graph rewriting is a popular tool for the optimisation and modification of graph expressions in domains such as compilers, machine learning and quantum computing. The underlying data structures are often port graphs - graphs with labels at…

Data Structures and Algorithms · Computer Science 2025-03-27 Luca Mondada , Pablo Andrés-Martínez

Evolutionary computing, particularly genetic algorithm (GA), is a combinatorial optimization method inspired by natural selection and the transmission of genetic information, which is widely used to identify optimal solutions to complex…

Neural and Evolutionary Computing · Computer Science 2024-12-31 Shanqing Yu , Meng Zhou , Jintao Zhou , Minghao Zhao , Yidan Song , Yao Lu , Zeyu Wang , Qi Xuan

Motivation: Inferring the structure of gene regulatory networks from high--throughput datasets remains an important and unsolved problem. Current methods are hampered by problems such as noise, low sample size, and incomplete…

Quantitative Methods · Quantitative Biology 2017-12-04 Phan Nguyen , Rosemary Braun

Programs with high levels of complexity often face challenges in adjusting execution parameters, particularly when these parameters vary based on the execution context. These dynamic parameters significantly impact the program's…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-18 Joao B. Fernandes , Felipe H. S. da Silva , Samuel Xavier-de-Souza , Italo A. S. Assis

Graph Neural Networks (GNNs) have become a popular approach for various applications, ranging from social network analysis to modeling chemical properties of molecules. While GNNs often show remarkable performance on public datasets, they…

Machine Learning · Computer Science 2022-02-03 Krzysztof Sadowski , Michał Szarmach , Eddie Mattia

Inference of gene regulatory networks has been an active area of research for around 20 years, leading to the development of sophisticated inference algorithms based on a variety of assumptions and approaches. With the always increasing…

Molecular Networks · Quantitative Biology 2022-11-03 Malvina Marku , Vera Pancaldi