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Determining the interaction strength between proteins and small molecules is key to analyzing their biological function. Quantum-mechanical calculations such as \emph{Density Functional Theory} (DFT) give accurate and theoretically…

Data Structures and Algorithms · Computer Science 2016-06-13 Moritz von Looz , Mario Wolter , Christoph R. Jacob , Henning Meyerhenke

The limits of molecular dynamics (MD) simulations of macromolecules are steadily pushed forward by the relentless developments of computer architectures and algorithms. This explosion in the number and extent (in size and time) of MD…

This monograph is about discrete energy minimization for discrete graphical models. It considers graphical models, or, more precisely, maximum a posteriori inference for graphical models, purely as a combinatorial optimization problem.…

Optimization and Control · Mathematics 2020-01-27 Bogdan Savchynskyy

Unlike existing work in deep neural network (DNN) graphs optimization for inference performance, we explore DNN graph optimization for energy awareness and savings for power- and resource-constrained machine learning devices. We present a…

Machine Learning · Computer Science 2026-01-27 Yu Wang , Rong Ge , Shuang Qiu

We consider a discrete-time model of continuous-time distributed optimization over dynamic directed-graphs (digraphs) with applications to distributed learning. Our optimization algorithm works over general strongly connected dynamic…

Optimization and Control · Mathematics 2024-03-27 Mohammadreza Doostmohammadian , Wei Jiang , Muwahida Liaquat , Alireza Aghasi , Houman Zarrabi

The problem of finding a minimum-weight connected dominating set (CDS) of a given undirected graph has been studied actively, motivated by operations of wireless ad hoc networks. In this paper, we formulate a new stochastic variant of the…

Data Structures and Algorithms · Computer Science 2020-01-01 Takuro Fukunaga

An analysis of the network defined by the potential energy minima of multi-atomic systems and their connectivity via reaction pathways that go through transition states allows to understand important characteristics like thermodynamic,…

Materials Science · Physics 2016-08-03 Bastian Schaefer , Stefan Goedecker

We introduce an FFT-based solver for the combinatorial continuous maximum flow discretization applied to computing the minimum cut through heterogeneous microstructures. Recently, computational methods were introduced for computing the…

Computational Engineering, Finance, and Science · Computer Science 2021-09-30 Felix Ernesti , Matti Schneider

This paper investigates the energy complexity of distributed graph problems in multi-hop radio networks, where the energy cost of an algorithm is measured by the maximum number of awake rounds of a vertex. Recent works revealed that some…

Data Structures and Algorithms · Computer Science 2023-04-11 Yi-Jun Chang

Graphs are a natural representation of data from various contexts, such as social connections, the web, road networks, and many more. In the last decades, many of these networks have become enormous, requiring efficient algorithms to cut…

Data Structures and Algorithms · Computer Science 2021-08-11 Alexander Noe

Energy saving is becoming an important issue in the design and use of computer networks. In this work we propose a problem that considers the use of rate adaptation as the energy saving strategy in networks. The problem is modeled as an…

Networking and Internet Architecture · Computer Science 2013-02-04 Lin Wang , Antonio Fernández Anta , Fa Zhang , Chenying Hou , Zhiyong Liu

Optimization of atomic structures presents a challenging problem, due to their highly rough and non-convex energy landscape, with wide applications in the fields of drug design, materials discovery, and mechanics. Here, we present a graph…

Machine Learning · Computer Science 2023-06-21 Vaibhav Bihani , Sahil Manchanda , Srikanth Sastry , Sayan Ranu , N. M. Anoop Krishnan

Real-world optimization problems are generally not just black-box problems, but also involve mixed types of inputs in which discrete and continuous variables coexist. Such mixed-space optimization possesses the primary challenge of modeling…

Machine Learning · Computer Science 2022-02-09 Jaeyeon Ahn , Taehyeon Kim , Seyoung Yun

This paper proposes distributed discrete-time algorithms to cooperatively solve an additive cost optimization problem in multi-agent networks. The striking feature lies in the use of only the sign of relative state information between…

Systems and Control · Computer Science 2018-12-11 Jiaqi Zhang , Keyou You , Tamer Başar

Graph states are versatile resources for various quantum information processing tasks, including measurement-based quantum computing and quantum repeaters. Although the type-II fusion gate enables all-optical generation of graph states by…

Quantum Physics · Physics 2023-12-25 Seok-Hyung Lee , Hyunseok Jeong

We present a novel energy-based numerical analysis of semilinear diffusion-reaction boundary value problems. Based on a suitable variational setting, the proposed computational scheme can be seen as an energy minimisation approach. More…

Numerical Analysis · Mathematics 2022-02-16 Mario Amrein , Pascal Heid , Thomas P. Wihler

Shape-based regularization has proven to be a useful method for delineating objects within noisy images where one has prior knowledge of the shape of the targeted object. When a collection of possible shapes is available, the specification…

Computer Vision and Pattern Recognition · Computer Science 2014-05-05 Joshua C. Chang , Tom Chou

Energies with high-order non-submodular interactions have been shown to be very useful in vision due to their high modeling power. Optimization of such energies, however, is generally NP-hard. A naive approach that works for small problem…

Computer Vision and Pattern Recognition · Computer Science 2013-10-09 Carl Olsson , Johannes Ulen , Yuri Boykov , Vladimir Kolmogorov

Energy minimization algorithms, such as graph cuts, enable the computation of the MAP solution under certain probabilistic models such as Markov random fields. However, for many computer vision problems, the MAP solution under the model is…

Computer Vision and Pattern Recognition · Computer Science 2013-07-31 Yongsub Lim , Kyomin Jung , Pushmeet Kohli

A useful approach to the mathematical analysis of large-scale biological networks is based upon their decompositions into monotone dynamical systems. This paper deals with two computational problems associated to finding decompositions…

Molecular Networks · Quantitative Biology 2007-05-23 Bhaskar DasGupta , German Andres Enciso , Eduardo Sontag , Yi Zhang
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