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Emulate the gating mechanism of ionic channels in neurons, we present a mathematical model for the time constant of dynamical systems. Our model is an analytical continues function. The analyses give evidence that one can adjust the…

Cell Behavior · Quantitative Biology 2016-03-29 S. H. Sabzpoushana , A. Ghajarjazyb , M. Nadjafikhahc

This work theoretically studies stochastic neural networks, a main type of neural network in use. We prove that as the width of an optimized stochastic neural network tends to infinity, its predictive variance on the training set decreases…

Machine Learning · Computer Science 2022-05-25 Liu Ziyin , Hanlin Zhang , Xiangming Meng , Yuting Lu , Eric Xing , Masahito Ueda

Stochastic models of biochemical reaction networks are widely used to capture intrinsic noise in cellular systems. The typical formulation of these models are based on Markov processes for which there is extensive research on efficient…

Molecular Networks · Quantitative Biology 2025-12-03 Thomas P. Steele , David J. Warne

We consider models of the population or opinion dynamics which result in the non-linear stochastic differential equations (SDEs) exhibiting the spurious long-range memory. In this context, the correspondence between the description of the…

Physics and Society · Physics 2019-10-28 Vygintas Gontis , Aleksejus Kononovicius

Stochastic reaction networks, which are usually modeled as continuous-time Markov chains on $\mathbb Z^d_{\ge 0}$, and simulated via a version of the "Gillespie algorithm," have proven to be a useful tool for the understanding of processes,…

Probability · Mathematics 2025-07-15 David F. Anderson , Aidan S. Howells

We introduce a new class of time-continuous recurrent neural network models. Instead of declaring a learning system's dynamics by implicit nonlinearities, we construct networks of linear first-order dynamical systems modulated via nonlinear…

Machine Learning · Computer Science 2020-12-16 Ramin Hasani , Mathias Lechner , Alexander Amini , Daniela Rus , Radu Grosu

Mathematical models of biological neural networks are associated to a rich and complex class of stochastic processes. In this paper, we consider a simple {\em plastic} neural network whose {\em connectivity/synaptic strength} $(W(t))$…

Probability · Mathematics 2021-06-30 Philippe Robert , Gaetan Vignoud

In this work we propose a new class of long-memory models with time-varying fractional parameter. In particular, the dynamics of the long-memory coefficient, $d$, is specified through a stochastic recurrence equation driven by the score of…

Methodology · Statistics 2018-12-19 Luisa Bisaglia , Matteo Grigoletto

Latent position models are widely used for the analysis of networks in a variety of research fields. In fact, these models possess a number of desirable theoretical properties, and are particularly easy to interpret. However, statistical…

Computation · Statistics 2023-03-08 Riccardo Rastelli , Florian Maire , Nial Friel

Based on the theory of stochastic chemical kinetics, the inherent randomness and stochasticity of biochemical reaction networks can be accurately described by discrete-state continuous-time Markov chains. The analysis of such processes is,…

Numerical Analysis · Mathematics 2014-10-14 Andreychenko Alexander , Mikeev Linar , Wolf Verena

Biological systems represent time from microseconds to years. An important gap in our knowledge concerns the mechanisms for encoding time intervals of hundreds of milliseconds to minutes that matter for tasks like navigation, communication,…

Neurons and Cognition · Quantitative Biology 2025-05-22 Raphaël Lafond-Mercier , Leonard Maler , Avner Wallach , André Longtin

This paper studies an input-driven one-state differential equation model initially developed for an experimentally demonstrated dynamic molecular switch that switches like synapses in the brain do. The linear-in-the-state and…

Machine Learning · Computer Science 2025-08-22 H. I. Nurdin , C. A. Nijhuis

Thought to be responsible for memory, synaptic plasticity has been widely studied in the past few decades. One example of plasticity models is the popular Spike Timing Dependent Plasticity (STDP). The huge litterature of STDP models are…

Probability · Mathematics 2018-03-02 Pascal Helson

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

Time series forecasting based on deep architectures has been gaining popularity in recent years due to their ability to model complex non-linear temporal dynamics. The recurrent neural network is one such model capable of handling…

Machine Learning · Computer Science 2021-06-28 Zexuan Yin , Paolo Barucca

How can we efficiently propagate uncertainty in a latent state representation with recurrent neural networks? This paper introduces stochastic recurrent neural networks which glue a deterministic recurrent neural network and a state space…

Machine Learning · Statistics 2016-11-15 Marco Fraccaro , Søren Kaae Sønderby , Ulrich Paquet , Ole Winther

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

Neurons and Cognition · Quantitative Biology 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

The study of temporal networks in discrete time has yielded numerous insights into time-dependent networked systems in a wide variety of applications. For many complex systems, however, it is useful to develop continuous-time models of…

Social and Information Networks · Computer Science 2021-02-10 Xinzhe Zuo , Mason A Porter

This paper introduces a new neural network model that aims to mimic the biological brain more closely by structuring the network as a complete directed graph that processes continuous data for each timestep. Current neural networks have…

Neural and Evolutionary Computing · Computer Science 2024-01-10 Frank Li

Stochastic processes defined on integer valued state spaces are popular within the physical and biological sciences. These models are necessary for capturing the dynamics of small systems where the individual nature of the populations…

Machine Learning · Statistics 2024-04-15 Luke O'Loughlin , John Maclean , Andrew Black