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The main target of retrosynthesis is to recursively decompose desired molecules into available building blocks. Existing template-based retrosynthesis methods follow a template selection stereotype and suffer from limited training…

Chemical Physics · Physics 2022-12-26 Chaochao Yan , Peilin Zhao , Chan Lu , Yang Yu , Junzhou Huang

In recent years, deep learning techniques have been developed to improve the performance of program synthesis from input-output examples. Albeit its significant progress, the programs that can be synthesized by state-of-the-art approaches…

Machine Learning · Computer Science 2018-03-09 Xinyun Chen , Chang Liu , Dawn Song

Most work on query optimization has concentrated on loop-free queries. However, data science and machine learning workloads today typically involve recursive or iterative computation. In this work, we propose a novel framework for…

Databases · Computer Science 2022-02-22 Yisu Remy Wang , Mahmoud Abo Khamis , Hung Q. Ngo , Reinhard Pichler , Dan Suciu

Deploying neural networks on edge devices entails a careful balance between the energy required for inference and the accuracy of the resulting classification. One technique for navigating this tradeoff is approximate computing: the process…

Machine Learning · Computer Science 2025-09-18 Morteza Rezaalipour , Francesco Costa , Marco Biasion , Rodrigo Otoni , George A. Constantinides , Laura Pozzi

Template-based synthesis, also known as sketching, is a localized approach to program synthesis in which the programmer provides not only a specification, but also a high-level ``sketch'' of the program. The sketch is basically a partial…

Programming Languages · Computer Science 2024-03-04 Amir Kafshdar Goharshady , S. Hitarth , Fatemeh Mohammadi , Harshit J Motwani

Program synthesis is the task of automatically generating expressions that satisfy a given specification. Program synthesis techniques have been used to automate the generation of loop invariants in code, synthesize function summaries, and…

Logic in Computer Science · Computer Science 2020-10-13 Elizabeth Polgreen , Sanjit A. Seshia

Designing synthetically accessible molecules and recommending analogs to unsynthesizable molecules are important problems for accelerating molecular discovery. We reconceptualize both problems using ideas from program synthesis. Drawing…

Biomolecules · Quantitative Biology 2025-03-04 Michael Sun , Alston Lo , Minghao Guo , Jie Chen , Connor Coley , Wojciech Matusik

Aggregation functions are widely used in answer set programming for representing and reasoning on knowledge involving sets of objects collectively. Current implementations simplify the structure of programs in order to optimize the overall…

Artificial Intelligence · Computer Science 2020-02-19 Mario Alviano , Wolfgang Faber , Martin Gebser

We prove that certain formulations of program synthesis and reachability are equivalent. Specifically, our constructive proof shows the reductions between the template-based synthesis problem, which generates a program in a pre-specified…

Programming Languages · Computer Science 2019-03-29 ThanhVu Nguyen , Westley Weimer , Deepak Kapur , Stephanie Forrest

The automatic generation of computer programs is one of the main applications with practical relevance in the field of evolutionary computation. With program synthesis techniques not only software developers could be supported in their…

Neural and Evolutionary Computing · Computer Science 2021-08-30 Dominik Sobania , Dirk Schweim , Franz Rothlauf

We propose a new synthesis algorithm that can efficiently search programs with local variables (e.g., those introduced by lambdas). Prior bottom-up synthesis algorithms are not able to evaluate programs with free local variables, and…

Programming Languages · Computer Science 2023-11-08 Xiang Li , Xiangyu Zhou , Rui Dong , Yihong Zhang , Xinyu Wang

This work introduces (1) a technique that allows large language models (LLMs) to leverage user-provided code when solving programming tasks and (2) a method to iteratively generate modular sub-functions that can aid future code generation…

Machine Learning · Computer Science 2023-12-05 Patrick Hajali , Ignas Budvytis

Machine translation systems are expected to cope with various types of constraints in many practical scenarios. While neural machine translation (NMT) has achieved strong performance in unconstrained cases, it is non-trivial to impose…

Computation and Language · Computer Science 2022-10-24 Shuo Wang , Peng Li , Zhixing Tan , Zhaopeng Tu , Maosong Sun , Yang Liu

We present a new domain-agnostic synthesis technique for generating programs from input-output examples. Our method, called metric program synthesis, relaxes the well-known observational equivalence idea (used widely in bottom-up…

Programming Languages · Computer Science 2022-10-12 John Feser , Isil Dillig , Armando Solar-Lezama

We consider the problem of type-directed component based synthesis where, given a set of (typed) components and a query type, the goal is to synthesize a term that inhabits the query. Classical approaches based on proof search in…

Programming Languages · Computer Science 2022-04-01 Zheng Guo , Michael James , David Justo , Jiaxiao Zhou , Ziteng Wang , Ranjit Jhala , Nadia Polikarpova

Program synthesis aims to {\it automatically} find programs from an underlying programming language that satisfy a given specification. While this has the potential to revolutionize computing, how to search over the vast space of programs…

Neural and Evolutionary Computing · Computer Science 2022-03-01 Yuan Yuan , Wolfgang Banzhaf

A key consideration when training an LLM is whether the target language is more or less resourced, for example English compared to Welsh, or Python compared to Excel. Typical training data for programming languages consists of real program…

Computation and Language · Computer Science 2026-05-13 Nick McKenna , Xinnuo Xu , Jack Williams , Nick Wilson , Benjamin Van Durme , Christian Poelitz

The work presented in this thesis seeks to improve programmer productivity in the following ways: - by reducing the amount of code that has to be written to construct an application; - by increasing the reliability of the code written; and…

Programming Languages · Computer Science 2010-06-18 Graham Kirby

Programming by example is the problem of synthesizing a program from a small set of input / output pairs. Recent works applying machine learning methods to this task show promise, but are typically reliant on generating synthetic examples…

Machine Learning · Computer Science 2019-11-11 Judith Clymo , Haik Manukian , Nathanaël Fijalkow , Adrià Gascón , Brooks Paige

Program synthesis and repair have emerged as an exciting area of research, driven by the potential for revolutionary advances in programmer productivity. Among most promising ideas emerging for synthesis are syntax-driven search,…

Programming Languages · Computer Science 2017-07-14 Manos Koukoutos , Mukund Raghothaman , Etienne Kneuss , Viktor Kuncak