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Motivated by the structure of networks of cross-linked cytoskeletal biopolymers, we study the orientationally ordered phases in two-dimensional networks of randomly cross-linked semiflexible polymers. We consider permanent cross-links which…

Soft Condensed Matter · Physics 2011-03-08 Martin Kiemes , Panayotis Benetatos , Annette Zippelius

Shape-morphing networks of mesoscale filaments are a common hierarchical feature in biology and hold significant potential for a range of technological applications, from micro-muscles to shape-morphing optical devices. Here, we demonstrate…

Here, we provide an overview of theoretical approaches to semiflexible polymers and their networks. Such semiflexible polymers have large bending rigidities that can compete with the entropic tendency of a chain to crumple up into a random…

Soft Condensed Matter · Physics 2016-05-25 Chase P. Broedersz , Fred. C. MacKintosh

Despite their considerable practical and biological applications, the link between molecular properties, assembly conditions and self-organized structure in confined polymer solutions remains elusive. Here, we explore the lyotropic nematic…

Soft Condensed Matter · Physics 2023-03-21 Maxime M. C. Tortora , Daniel Jost

We study the mechanical stiffening behavior in two-dimensional (2D) cross-linked networks of semiflexible biopolymer filaments under simple shear. Filamental constituents immersed in a fluid undergo thermally excited bending motions.…

Biological Physics · Physics 2007-05-23 T. Van Dillen , P. R. Onck , E. Van der Giessen

Living matter moves, deforms, and organizes itself. In cells this is made possible by networks of polymer filaments and crosslinking molecules that connect filaments to each other and that act as motors to do mechanical work on the network.…

Soft Condensed Matter · Physics 2020-12-15 Sebastian Fürthauer , Daniel J Needleman , Michael J. Shelley

Many-body interactions in systems of active matter can cause particles to move collectively and self-organize into dynamic structures with long-range order. In cells, the self-assembly of cytoskeletal filaments is critical for cellular…

Soft Condensed Matter · Physics 2020-05-26 Jeffrey M. Moore , Matthew A. Glaser , Meredith D. Betterton

We systematically explore the self-assembly of semi-flexible polymers in deformable spherical confinement across a wide regime of chain stiffness, contour lengths and packing fractions by means of coarse-grained molecular dynamics…

Soft Condensed Matter · Physics 2021-07-12 Maxime M. C. Tortora , Daniel Jost

We study the effects of intrinsic sequence-dependent curvature for a two dimensional semiflexible biopolymer with short-range correlation in intrinsic curvatures. We show exactly that when not subjected to any external force, such a system…

Soft Condensed Matter · Physics 2015-05-14 Zicong Zhou , Bela Joos

Tissues commonly consist of cells embedded within a fibrous biopolymer network. Whereas cell-free reconstituted biopolymer networks typically soften under applied uniaxial compression, various tissues, including liver, brain, and fat, have…

We develop the theory of the coupling between in-plane order and out-of-plane geometry in twisted, two-dimensionally ordered filament bundles based on the non-linear continuum elasticity theory of columnar materials. We show that twisted…

Soft Condensed Matter · Physics 2015-06-03 Gregory M. Grason

The Extra-Cellular-Matrix (ECM) is a complex interconnected 3D network that provides structural support for the cells and tissues and defines organ architecture key for their healthy functioning. However, the intimate mechanisms by which…

Packing of particles in confined environments is a common problem in multiple fields. Here, based on the two-dimensional Hertzian particle model, we study the packing of deformable spherical particles under compression, and reveal the…

Soft Condensed Matter · Physics 2020-07-01 Zhenwei Yao

A collection of thin structures buckle, bend, and bump into each-other when confined. This contact can lead to the formation of patterns: hair will self-organize in curls; DNA strands will layer into cell nuclei; paper, when crumpled, will…

Soft Condensed Matter · Physics 2023-04-19 Arman Guerra , Anja Slim , Douglas P. Holmes , Ousmane Kodio

Strain stiffening of protein networks is explored by means of a finite strain analysis of a two-dimensional network model of cross-linked semiflexible filaments. The results show that stiffening is caused by non-affine network…

Soft Condensed Matter · Physics 2009-11-11 P. R. Onck , T. Koeman , T. Van Dillen , E. Van der Giessen

The elasticity of disordered and polydisperse polymer networks is a fundamental problem of soft matter physics that is still open. Here, we self-assemble polymer networks via simulations of a mixture of bivalent and tri- or tetravalent…

Biopolymer networks from the intracellular to tissue scale display high rigidity and tensile stress while having coordinations well below the normal threshold for mechanical rigidity. The elastic filaments in these networks are often…

Soft Condensed Matter · Physics 2024-11-15 Marco Aurelio Galvani Cunha , John C. Crocker , Andrea J. Liu

We present a model for disordered 3D fiber networks to study their linear and nonlinear elasticity over a wide range of network densities and fiber lengths. In contrast to previous 2D models, these 3D networks with binary cross-links are…

Soft Condensed Matter · Physics 2015-05-30 C. P. Broedersz , M. Sheinman , F. C. MacKintosh

Through extensive Monte Carlo simulations, we systematically study the effect of chain stiffness on the packing ability of linear polymers composed of hard spheres in extremely confined monolayers, corresponding effectively to 2D films.…

Twisted assemblies of filaments in ropes, cables and bundles are essential structural elements in wide use in macroscopic materials as well as within the cells and tissues of living organisms. We develop the unique, non-linear elastic…

Soft Condensed Matter · Physics 2015-05-18 Gregory M. Grason
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