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The first experimental study of the low-temperature kinetics of the gas-phase reaction of NH2 with formaldehyde (CH2O) has been performed. This reaction has previously been suggested as a source of formamide (NH2CHO) in interstellar…

Astrophysics of Galaxies · Physics 2022-10-05 Kevin M. Douglas , Daniel Lucas , Catherine Walsh , Niclas A. West , Mark A. Blitz , Dwayne E. Heard

Interstellar formamide (NH2CHO) has recently attracted significant attention due to its potential role as a molecular building block in the formation of precursor biomolecules relevant for the origin of life. Its formation, whether on the…

Earth and Planetary Astrophysics · Physics 2018-10-09 Albert Rimola , Dimitrios Skouteris , Nadia Balucani , Cecilia Ceccarelli , Joan Enrique-Romero , Vianney Taquet , Piero Ugliengo

Formamide has a key role in prebiotic chemistry as it is the simplest molecule containing the four most important atoms from a biological point of view: hydrogen, carbon, nitrogen and oxygen. Due to its importance, the formation of this…

Chemical Physics · Physics 2021-11-02 Berta Martínez-Bachs , Albert Rimola

The formation mechanism of interstellar formamide (NH$_2$CHO), a key prebiotic precursor, is currently a matter of hot debate within the astrochemistry community, with both gas-phase and grain-surface chemical pathways having been proposed…

Astrophysics of Galaxies · Physics 2024-11-04 Ana López-Sepulcre , Claudio Codella , Cecilia Ceccarelli , Linda Podio , Juliette Robuschi

Investigating how formamide forms in the interstellar medium is a hot topic in astrochemistry, which can contribute to our understanding of the origin of life on Earth. We have constructed a QM/MM model to simulate the hydrogenation of…

Chemical Physics · Physics 2016-11-23 Lei Song , Johannes Kästner

Based on recent work, formamide might be a potentially very important molecule in the emergence of terrestrial life. Although detected in the interstellar medium for decades, its formation route is still debated, whether in the gas phase or…

Solar and Stellar Astrophysics · Physics 2017-07-19 D. Skouteris , F. Vazart , C. Ceccarelli , N. Balucani , C. Puzzarini , V. Barone

Formamide (NH2CHO) has been proposed as a pre-biotic precursor with a key role in the emergence of life on Earth. While this molecule has been observed in space, most of its detections correspond to high-mass star-forming regions. Motivated…

Context: Modern versions of the Miller-Urey experiment claim that formamide (NH$_2$CHO) could be the starting point for the formation of metabolic and genetic macromolecules. Intriguingly, formamide is indeed observed in regions forming…

Syn-glycolamide, a glycine isomer, has recently been detected in the G+0.693-0.027 molecular cloud. Investigations on its formation in the interstellar medium could offer insights into synthetic routes leading to glycine in prebiotic…

Astrophysics of Galaxies · Physics 2025-04-25 Jessica Perrero , Silvia Alessandrini , Hexu Ye , Cristina Puzzarini , Albert Rimola

Formamide (NH$_2$CHO) has been identified as a potential precursor of a wide variety of organic compounds essential to life, and many biochemical studies propose it likely played a crucial role in the context of the origin of life on our…

Solar and Stellar Astrophysics · Physics 2019-10-25 Ana López-Sepulcre , Nadia Balucani , Cecilia Ceccarelli , Claudio Codella , Francois Dulieu , Patrice Theulé

The astronomical detection of formamide (NH$_2$CHO) toward various star-forming regions and in cometary material implies that the simplest amide might have an early origin in dark molecular clouds at low temperatures. Laboratory studies…

Astrophysics of Galaxies · Physics 2022-07-20 K. -J. Chuang , C. J\{"a}ger , S. A. Krasnokutski , D. Fulvio , Th. Henning

Explaining the formation pathways of amides on ice-grain mantels is crucial to understanding the prebiotic chemistry in an interstellar medium. In this computational study, we explore different radical-neutral formation pathways for some of…

Astrophysics of Galaxies · Physics 2024-07-10 Gabriela Silva-Vera , Giulia M. Bovolenta , Namrata Rani , Sebastian Vera , Stefan Vogt-Geisse

Context. As a building block for amino acids, formamide (NH$_2$CHO) is an important molecule in astrobiology and astrochemistry, but its formation path in the interstellar medium is not understood well. Aims. We aim to find empirical…

Formamide (NH2CHO) is considered an important prebiotic molecule because of its potential to form peptide bonds. It was recently detected in the atmosphere of the HH 212 protostellar disk on the Solar-System scale where planets will form.…

Astrophysics of Galaxies · Physics 2022-09-28 Chin-Fei Lee , Claudio Codella , Cecilia Ceccarelli , Ana Lopez-Sepulcre

Urea is a prebiotic molecule that has been detected in few sources of the interstellar medium (ISM) and in Murchison meteorite. Being stable against ultraviolet radiation and high-energy electron bombardment, urea is expected to be present…

Astrophysics of Galaxies · Physics 2023-11-03 J. Perrero , A. Rimola

Glycolaldehyde (HOCH2CHO) is the most straightforward sugar detected in the Interstellar Medium (ISM) and participates in the formation pathways of molecules fundamental to life, red such as ribose and derivatives. Although detected in…

Astrophysics of Galaxies · Physics 2023-02-07 Mateus A. M. Paiva , Sergio Pilling , Edgar Mendoza , Breno R. L. Galvão , Heitor A. De Abreu

Water is an important reservoir species for oxygen in interstellar space and plays a key role in the physics of star formation through cooling by far-infrared emission. Whilst water vapour is present at high abundances in the outflows of…

Astrophysics of Galaxies · Physics 2013-08-20 Kevin Hickson , Jean-Christophe Loison , Philippe Caubet

Context. The carbamoyl radical (H2NCO) is believed to play a central role in the ice-grain chemistry of crucial interstellar complex organic molecules as formamide and acetamide. Yet, little is known about this radical that remains elusive…

Hydroxylamine, NH2OH, is one of the already detected interstellar molecules with the highest prebiotic potential. Yet, the abundance of this molecule found by astronomical observations is rather low for a relatively simple molecule, $\sim$…

Astrophysics of Galaxies · Physics 2023-03-29 Gerán Molpeceres , Víctor. M. Rivilla , Kenji Furuya , Johannes Kästner , Belén Maté , Yuri Aikawa

Formamide (NH$_2$CHO) has previously been detected in several star-forming regions and is thought to be a precursor for different prebiotic molecules. Its formation mechanism is still debated, however. Observations of formamide, related…

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