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Purpose of review: Artificial intelligence (AI) has become popular in medical applications, specifically as a clinical support tool for computer-aided diagnosis. These tools are typically employed on medical data (i.e., image, molecular…

Machine Learning · Computer Science 2022-06-08 Ahmad Chaddad , Yousef Katib , Lama Hassan

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang

The rapid growth and diversity in service offerings and the ensuing complexity of information technology ecosystems present numerous management challenges (both operational and strategic). Instrumentation and measurement technology is, by…

Software Engineering · Computer Science 2012-06-26 Moises Goldszmidt

Machine learning applications are becoming increasingly pervasive in our society. Since these decision-making systems rely on data-driven learning, risk is that they will systematically spread the bias embedded in data. In this paper, we…

Machine Learning · Statistics 2023-02-09 Alessandro Castelnovo , Riccardo Crupi , Nicole Inverardi , Daniele Regoli , Andrea Cosentini

We study the challenges of applying deep learning to gene expression data. We find experimentally that there exists non-linear signal in the data, however is it not discovered automatically given the noise and low numbers of samples used in…

Genomics · Quantitative Biology 2018-06-20 Francis Dutil , Joseph Paul Cohen , Martin Weiss , Georgy Derevyanko , Yoshua Bengio

Current metagenomic analysis algorithms require significant computing resources, can report excessive false positives (type I errors), may miss organisms (type II errors / false negatives), or scale poorly on large datasets. This paper…

Databases · Computer Science 2015-01-23 Ashley Mae Conard , Stephanie Dodson , Jeremy Kepner , Darrell Ricke

Gene regulation in Eukaryotes is mainly effected through transcription factors binding to rather short recognition motifs generally located upstream of the coding region. We present a novel computational method to identify regulatory…

Disordered Systems and Neural Networks · Physics 2007-05-23 M. Caselle , F. Di Cunto , P. Provero

Artificial neurons built on synthetic gene networks have potential applications ranging from complex cellular decision-making to bioreactor regulation. Furthermore, due to the high information throughput of natural systems, it provides an…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Sihao Huang

As the use of Generative Artificial Intelligence tools have grown in higher education and research, there have been increasing calls for transparency and granularity around the use and attribution of the use of these tools. Thus far, this…

Digital Libraries · Computer Science 2025-04-11 Kari D. Weaver

This study explores the benefits and challenges of integrating Artificial Intelligence with Agile software development methodologies, focusing on improving continuous integration and delivery. A systematic literature review and longitudinal…

Software Engineering · Computer Science 2023-05-16 Beatriz Cabrero-Daniel

Lean processes focus on doing only necessery things in an efficient way. Artificial intelligence and Machine Learning offer new opportunities to optimizing processes. The presented approach demonstrates an improvement of the test process by…

Software Engineering · Computer Science 2019-06-10 Alexander Poth , Quirin Beck , Andreas Riel

We present experiences and lessons learned from increasing data readiness of heterogeneous data for artificial intelligence projects using visual analysis methods. Increasing the data readiness level involves understanding both the data as…

Methodology · Statistics 2024-09-09 Mattias Tiger , Daniel Jakobsson , Anders Ynnerman , Fredrik Heintz , Daniel Jönsson

Artificial intelligence (AI) has significant potential to positively impact and advance medical imaging, including positron emission tomography (PET) imaging applications. AI has the ability to enhance and optimize all aspects of the PET…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Arkadiusz Sitek , Sangtae Ahn , Evren Asma , Adam Chandler , Alvin Ihsani , Sven Prevrhal , Arman Rahmim , Babak Saboury , Kris Thielemans

Artificial intelligence is more ubiquitous in multiple domains. Smartphones, social media platforms, search engines, and autonomous vehicles are just a few examples of applications that utilize artificial intelligence technologies to…

Machine Learning · Computer Science 2025-06-24 Teemu Niskanen , Tuomo Sipola , Olli Väänänen

Drug discovery is adapting to novel technologies such as data science, informatics, and artificial intelligence (AI) to accelerate effective treatment development while reducing costs and animal experiments. AI is transforming drug…

Artificial Intelligence · Computer Science 2023-07-14 Catrin Hasselgren , Tudor I. Oprea

The inference of gene-regulatory processes from gene-expression data belongs to the major challenges of computational systems biology. Here we address the problem from a statistical-physics perspective and develop a message-passing…

Quantitative Methods · Quantitative Biology 2008-12-05 A. Braunstein , A. Pagnani , M. Weigt , R. Zecchina

Introduction The focus of analyzing data from microarray experiments and extracting biological insight from such data has experienced a shift from identification of individual genes in association with a phenotype to that of biological…

Genomics · Quantitative Biology 2015-08-10 Lei Zhang , Linlin Wang , Pu Tian , Suyan Tian

Affymetrix Genechip microarrays are used widely to determine the simultaneous expression of genes in a given biological paradigm. Probes on the Genechip array are atomic entities which by definition are randomly distributed across the array…

Genomics · Quantitative Biology 2009-11-13 Radhakrishnan Nagarajan , Meenakshi Upreti

High-throughput data analyses are becoming common in biology, communications, economics and sociology. The vast amounts of data are usually represented in the form of matrices and can be considered as knowledge networks. Spectra-based…

Quantitative Methods · Quantitative Biology 2010-01-06 Viet-Anh Nguyen , Zdena Koukolikova-Nicola , Franco Bagnoli , Pietro Lio

Artificial intelligence (AI) is an extensive scientific discipline which enables computer systems to solve problems by emulating complex biological processes such as learning, reasoning and self-correction. This paper presents a…

Artificial Intelligence · Computer Science 2018-01-16 Javier Mata , Ignacio de Miguel , Ramó n J. Durá n , Noemí Merayo , Sandeep Kumar Singh , Admela Jukan , Mohit Chamania