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Fluorescence photoacoustic tomography (fPAT) is a molecular imaging modality that combines photoacoustic tomography (PAT) with fluorescence imaging to obtain high-resolution imaging of fluorescence distributions inside heterogeneous media.…

Analysis of PDEs · Mathematics 2019-09-27 Kui Ren , Rongting Zhang , Yimin Zhong

Photoacoustic tomography (PAT) is a hybrid medical imaging technique that offer high contrast and a high spatial resolution. One challenging mathematical problem associated with PAT is reconstructing the initial pressure of the wave…

Numerical Analysis · Mathematics 2024-07-16 Gyeongha Hwang , Gihyeon Jeon , Sunghwan Moon , Dabin Park

Photoacoustic tomography (PAT) is a rapidly-evolving medical imaging modality that combines optical absorption contrast with ultrasound imaging depth. One challenge in PAT is image reconstruction with inadequate acoustic signals due to…

Photoacoustic computed tomography (PACT) is a non-invasive imaging modality, similar to ultrasound, with wide-ranging medical applications. Conventional PACT images are degraded by wavefront distortion caused by the heterogeneous speed of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Tianao Li , Manxiu Cui , Cheng Ma , Emma Alexander

Objective:Optoacoustic (photoacoustic) tomography is aimed at reconstructing maps of the initial pressure rise induced by the absorption of light pulses in tissue. In practice, due to inaccurate assumptions in the forward model, noise and…

Medical Physics · Physics 2019-01-21 Jaya Prakash , Subhamoy Mandal , Daniel Razansky , Vasilis Ntziachristos

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. When the imaging…

Medical Physics · Physics 2016-11-15 Qiwei Sheng , Kun Wang , Thomas P. Matthews , Jun Xia , Liren Zhu , Lihong V. Wang , Mark A. Anastasio

Motion, e.g., due to patient movement or improper device calibration, is inevitable in many imaging modalities such as photoacoustic tomography (PAT) by a rotating system and can lead to undesirable motion artifacts in image…

Numerical Analysis · Mathematics 2016-09-28 Julianne Chung , Linh Nguyen

In this paper we study the problem of photoacoustic inversion in a weakly attenuating medium. We present explicit reconstruction formulas in such media and show that the inversion based on such formulas is moderately ill--posed. Moreover,…

Numerical Analysis · Mathematics 2018-01-17 Otmar Scherzer , Cong Shi

Photo-acoustic Tomography (PAT) and Thermo-acoustic Tomography (TAT) are medical imaging modalities that combine the high contrast of radiative properties of tissues with the high resolution of ultrasound. In both modalities, a first step…

Medical Physics · Physics 2012-02-15 Guillaume Bal

This paper proposes quantum image reconstruction. Input-triggered selection of an image among many stored ones, and its reconstruction if the input is occluded or noisy, has been simulated by a computer program implementable in a real…

Quantum Physics · Physics 2009-11-10 Mitja Perus , Horst Bischof , Chu Kiong Loo

Photoacoustic tomography (PAT) is a novel and rapidly promising technique in the field of medical imaging, based on the generation of acoustic waves inside an object of interest by stimulating non-ionizing laser pulses. This acoustic wave…

Analysis of PDEs · Mathematics 2022-02-08 Hyungyeong Jung , Sunghwan Moon

Photoacoustic tomography (PAT) has the potential to recover morphological and functional tissue properties with high spatial resolution. However, previous attempts to solve the optical inverse problem with supervised machine learning were…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Melanie Schellenberg , Janek Gröhl , Kris K. Dreher , Jan-Hinrich Nölke , Niklas Holzwarth , Minu D. Tizabi , Alexander Seitel , Lena Maier-Hein

We propose a model-based image reconstruction method for photoacoustic tomography(PAT) involving a novel form of regularization and demonstrate its ability to recover good quality images from significantly reduced size datasets. The…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Nadaparambil Aravindakshan Rejesh , Sandeep Kumar Kalva , Manojit Pramanik , Muthuvel Arigovindan

Recently, a novel measurement setup has been introduced to photoacoustic tomography, that collects data in the form of projections of the full 3D acoustic pressure distribution at a certain time instant. Existing imaging algorithms for this…

Numerical Analysis · Mathematics 2018-08-03 Gerhard Zangerl , Markus Haltmeier , Linh V. Nguyen , Robert Nuster

This paper studies inverse problems in quantitative photoacoustic tomography with additional optical current data supplemented from diffuse optical tomography. We propose a three-stage image reconstruction method for the simultaneous…

Numerical Analysis · Mathematics 2025-01-27 Yinxi Pan , Kui Ren , Shanyin Tong

While in standard photoacoustic imaging the propagation of sound waves is modeled by the standard wave equation, our approach is based on a generalized wave equation with variable sound speed and material density, respectively. In this…

Analysis of PDEs · Mathematics 2018-04-18 Alexander Beigl , Peter Elbau , Kamran Sadiq , Otmar Scherzer

Photoacoustic tomography (PAT) is an emerging and non-invasive hybrid imaging modality for visualizing light absorbing structures in biological tissue. The recently invented PAT systems using arrays of 64 parallel integrating line detectors…

Numerical Analysis · Mathematics 2018-08-31 Johannes Schwab , Stephan Antholzer , Robert Nuster , Markus Haltmeier

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Bowei Yao , Yi Zeng , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Yuyao Zhang , Jingyi Yu , Xiran Cai

In this article, we study several reconstruction methods for the inverse source problem of photoacoustic tomography (PAT) with spatially variable sound speed and damping. The backbone of these methods is the adjoint operators, which we…

Analysis of PDEs · Mathematics 2018-08-21 Linh V. Nguyen , Markus Haltmeier

Purpose: Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as the vessel topology and tissue oxygenation. While this capacity makes PAT a…