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Dynamic treatment regimes (DTRs) are personalized, adaptive, multi-stage treatment plans that adapt treatment decisions both to an individual's initial features and to intermediate outcomes and features at each subsequent stage, which are…

Machine Learning · Statistics 2022-09-22 Yichun Hu , Nathan Kallus

Major depressive disorder (MDD) presents challenges in diagnosis and treatment due to its complex and heterogeneous nature. Emerging evidence indicates that reward processing abnormalities may serve as a behavioral marker for MDD. To…

Machine Learning · Computer Science 2024-07-29 Xingche Guo , Donglin Zeng , Yuanjia Wang

Temporally dense single-person "small data" have become widely available thanks to mobile apps and wearable sensors. Many caregivers and self-trackers want to use these data to help a specific person change their behavior to achieve desired…

Methodology · Statistics 2025-09-30 Eric J. Daza , Igor Matias , Logan Schneider

A common challenge for decision makers is selecting actions whose rewards are unknown and evolve over time based on prior policies. For instance, repeated use may reduce an action's effectiveness (habituation), while inactivity may restore…

Machine Learning · Computer Science 2025-11-06 Fengxu Li , Stephanie M. Carpenter , Matthew P. Buman , Yonatan Mintz

Randomized experiments (a.k.a. A/B tests) are a powerful tool for estimating treatment effects, to inform decisions making in business, healthcare and other applications. In many problems, the treatment has a lasting effect that evolves…

Machine Learning · Computer Science 2022-10-17 Ziyang Tang , Yiheng Duan , Stephanie Zhang , Lihong Li

Conjoined collaborative robots, functioning as supernumerary robotic bodies (SRBs), can enhance human load tolerance abilities. However, in tasks involving physical interaction with humans, users may still adopt awkward, non-ergonomic…

Robotics · Computer Science 2026-02-02 Theodora Kastritsi , Marta Lagomarsino , Arash Ajoudani

Neurofeedback is a non-invasive brain training with long-term medical and non-medical applications. Despite the existence of several emotion regulation studies using neurofeedback, further investigation is needed to understand interactions…

Neurons and Cognition · Quantitative Biology 2020-06-19 Amin Dehghani , Hamid Soltanian-Zadeh , Gholam-Ali Hossein-Zadeh

Emotion regulation plays a key role in human behavior and overall well-being. Neurofeedback is a non-invasive self-brain training technique used for emotion regulation to enhance brain function and treatment of mental disorders through…

Neurons and Cognition · Quantitative Biology 2023-11-06 Amin Dehghani , Hamid Soltanian-Zadeh , Gholam-Ali Hossein-Zadeh

More than one million people commit suicide every year worldwide. The costs of daily cares, social stigma and treatment issues are still hard barriers to overcome in mental health. Most symptoms of mental disorders are related to the…

Music is increasingly being used as a therapeutic tool in the field of rehabilitation medicine and psychophysiology. One of the main key components of music is its temporal organization. The characteristics of neurocognitive processes…

Neurons and Cognition · Quantitative Biology 2023-03-20 Grigoriy Radchenko , Valeriia Demareva , Kirill Gromov , Irina Zayceva , Artem Rulev , Marina Zhukova , Andrey Demarev

This paper introduces a new modeling perspective in the public mental health domain to provide a robust interpretation of the relations between anxiety and depression, and the demographic and temporal factors. This perspective particularly…

Applications · Statistics 2026-01-30 Mustafa Cavus , Przemysław Biecek , Julian Tejada , Fernando Marmolejo-Ramos , Andre Faro

Not only does mobile health technology enable researchers to track changes in multiple longitudinal outcomes of interest and to record the occurrence of health-related events over time, but it also allows for the delivery of repeated…

For public health programs with limited resources, the ability to predict how behaviors change over time and in response to interventions is crucial for deciding when and to whom interventions should be allocated. Using data from a…

Machine Learning · Computer Science 2024-09-05 Roderick Seow , Yunfan Zhao , Duncan Wood , Milind Tambe , Cleotilde Gonzalez

Neurofeedback is a form of brain training in which subjects are fed back information about some measure of their brain activity which they are instructed to modify in a way thought to be functionally advantageous. Over the last twenty…

Neurons and Cognition · Quantitative Biology 2018-05-15 David Papo

Mixed Models for Repeated Measures (MMRMs) are ubiquitous when analyzing outcomes of clinical trials. However, the linearity of the fixed-effect structure in these models largely restrict their use to estimating treatment effects that are…

Methodology · Statistics 2023-01-23 Lars Lau Raket

In recent years, research interest in personalised treatments has been growing. However, treatment effect heterogeneity and possibly time-varying treatment effects are still often overlooked in clinical studies. Statistical tools are needed…

Methodology · Statistics 2023-10-27 Caterina Gregorio , Giovanni Baj , Giulia Barbati , Francesca Ieva

Mental fatigue related behavioral performance decline precipitates catastrophic accidents in sustained attention tasks. While existing neurophysiological systems effectively detect current behavioral performance, they often lack the…

Human-Computer Interaction · Computer Science 2026-05-12 Bo Sun , Liang Ma

Large language models (LLMs) offer novel opportunities to support health behavior change, yet existing work has narrowly focused on text-only interactions. Building on decades of HCI research on effective behavior change interactions, we…

Identifying patient subgroups with different treatment responses is an important task to inform medical recommendations, guidelines, and the design of future clinical trials. Existing approaches for treatment effect estimation primarily…

Methodology · Statistics 2025-12-10 Vincent Jeanselme , Chang Ho Yoon , Fabian Falck , Brian Tom , Jessica Barrett

Affective robotics research aims to better understand human social and emotional signals to improve human-robot interaction (HRI), and has been widely used during the last decade in multiple application fields. Past works have demonstrated,…

Robotics · Computer Science 2023-04-05 Micol Spitale , Hatice Gunes