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The colonization of unoccupied territory by invading species, known as range expansion, is a spatially heterogeneous non-equilibrium growth process. We introduce a two-species Eden growth model to analyze the interplay between…

Statistical Mechanics · Physics 2011-11-15 Jan-Timm Kuhr , Madeleine Leisner , Erwin Frey

Both community ecology and conservation biology seek further understanding of factors governing the advance of an invasive species. We model biological invasion as an individual-based, stochastic process on a two-dimensional landscape. An…

Populations and Evolution · Quantitative Biology 2010-07-12 Lauren O'Malley , G. Korniss , Thomas Caraco

When a biological population expands into new territory, genetic drift develops an enormous influence on evolution at the propagating front. In such range expansion processes, fluctuations in allele frequencies occur through stochastic…

Biological Physics · Physics 2018-12-24 Sherry Chu , Mehran Kardar , David R. Nelson , Daniel A. Beller

Mutations in a microbial population can increase the frequency of a genotype not only by increasing its exponential growth rate, but also by decreasing its lag time or adjusting the yield (resource efficiency). The contribution of multiple…

Populations and Evolution · Quantitative Biology 2018-02-15 Michael Manhart , Bharat V. Adkar , Eugene I. Shakhnovich

Urban expansion fronts display a robust local roughness exponent together with strongly dispersed growth and nonuniversal dynamic exponents. We show that this coexistence can arise from a disorder-controlled crossover in projected-front…

Physics and Society · Physics 2026-04-27 Martin Hendrick , Maximilian Trique , Gabriele Manoli

We study the genetic interfaces between two species of an expanding colony that consists of individual microorganisms that reproduce and undergo diffusion, both at the frontier and in the interior. Within the bulk of the colony, the genetic…

Biological Physics · Physics 2025-10-28 Jonathan Bauermann , David R. Nelson

A fundamental issue discussed in evolutionary biology is the transition from unicellular to multicellular organisms. Here we develop non-robust models provided in [1] and attempt to get robust models investigated how differentiation of…

Populations and Evolution · Quantitative Biology 2015-12-15 Denis Tverskoy

Recent microbial experiments suggest that enhanced genetic drift at the frontier of a two-dimensional range expansion can cause genetic sectoring patterns with fractal domain boundaries. Here, we propose and analyze a simple model of…

Populations and Evolution · Quantitative Biology 2008-12-12 Oskar Hallatschek , David R. Nelson

There is a pressing need to better understand how microbial populations respond to antimicrobial drugs, and to find mechanisms to possibly eradicate antimicrobial-resistant cells. The inactivation of antimicrobials by resistant microbes can…

Populations and Evolution · Quantitative Biology 2023-11-16 Lluís Hernández-Navarro , Matthew Asker , Alastair M. Rucklidge , Mauro Mobilia

A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences…

Biological Physics · Physics 2019-03-06 Robert Marsland , Wenping Cui , Joshua Goldford , Alvaro Sanchez , Kirill Korolev , Pankaj Mehta

As a population grows, spreading to new environments may favor specialization. In this paper, we introduce and explore a model for specialization at the front of a colony expanding synchronously into new territory. We show through numerical…

Biological Physics · Physics 2023-09-14 Lauren H. Li , Mehran Kardar

Cell colonies of bacteria, tumour cells and fungi, under nutrient limited growth conditions, exhibit complex branched growth patterns. In order to investigate this phenomenon we present a simple hybrid cellular automaton model of cell…

Biological Physics · Physics 2007-05-23 P. Gerlee , A. R. A Anderson

Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures routinely used in microbial research, bacteria in a…

Biological Physics · Physics 2017-01-13 Fred F. Farrell , Matti Gralka , Oskar Hallatschek , Bartlomiej Waclaw

Directed Percolation (DP) is a classic model for nonequilibrium phase transitions into a single absorbing state (fixation). It has been extensively studied by analytical and numerical techniques in diverse contexts. Recently, DP has…

Statistical Mechanics · Physics 2019-05-01 Jordan M. Horowitz , Mehran Kardar

Theoretical understanding of evolutionary dynamics in spatially structured populations often relies on non-spatial models. Biofilms are among such populations where a more accurate understanding is of theoretical interest and can reveal new…

Biological Physics · Physics 2021-05-26 Youness Azimzade , Abbas Ali Saberi

In the magnetic Eden model (MEM), particles have a spin and grow in contact with a thermal bath. Although Ising-like interactions affect the growth dynamics, deposited spins are frozen and not allowed to flip. This review article focuses on…

Statistical Mechanics · Physics 2009-11-13 Julián Candia , Ezequiel V. Albano

We study colonies of non-motile, rod-shaped bacteria growing on solid substrates. In our model, bacteria interact purely mechanically, by pushing each other away as they grow, and consume a diffusing nutrient. We show that mechanical…

Biological Physics · Physics 2015-06-15 F. D. C. Farrell , O. Hallatschek , D. Marenduzzo , B. Waclaw

Density-dependent diffusion is a widespread phenomenon in nature. We have examined the density-dependent diffusion behavior of some biological processes such as tumor growth and invasion [23]. Here, we extend our previous work by developing…

Statistical Mechanics · Physics 2022-02-14 Ahmed M. Fouad , Marwa M. Fouad

The stochastic Eden model of charged particles aggregation in two-dimensional systems is presented. This model is governed by two parameters: screening length of electrostatic interaction, $\lambda $, and short range attraction energy, $E$.…

Statistical Mechanics · Physics 2009-10-31 Y. V. Ivanenko , N. I. Lebovka , N. V. Vygornitskii

Frequency-dependent selection reflects the interaction between different species as they battle for limited resources in their environment. In a stochastic evolutionary game the species relative fitnesses guides the evolutionary dynamics…

Probability · Mathematics 2020-12-29 Lea Popovic , Liam Peuckert
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