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The illness-death model of a chronic disease consists of the states 'Normal', 'Disease' and 'Death'. In general, the transition rates between the states depend on three time scales: calendar time, age and duration of the chronic disease.…

Populations and Evolution · Quantitative Biology 2013-08-30 Ralph Brinks

Let $T\$ be a stopping time associated with a sequence of independent random variables $Z_{1},Z_{2},...$ . By applying a suitable change in the probability measure we present relations between the moment or probability generating functions…

Statistics Theory · Mathematics 2011-06-28 M. V. Boutsikas , A. C. Rakitzis , D. L. Antzoulakos

The recent interest in human dynamics has led researchers to investigate the stochastic processes that explain human behaviour in various contexts. Here we propose a generative model to capture the dynamics of survival analysis,…

Physics and Society · Physics 2015-09-30 Trevor Fenner , Mark Levene , George Loizou

We propose a stochastic model for evolution. Births and deaths of species occur with constant probabilities. Each new species is associated with a fitness sampled from the uniform distribution on [0,1]. Every time there is a death event…

Probability · Mathematics 2010-11-09 Herve Guiol , Fabio P. Machado , Rinaldo B. Schinazi

We study and compare equilibrium and aging dynamics on both sides of the ideal glass transition temperature $T_{MCT}$. In the context of a mean field model, we observe that all dynamical behaviors are determined by the energy distance…

Disordered Systems and Neural Networks · Physics 2009-10-06 Alexandre Lefèvre

Plant survival is a key factor in forest dynamics and survival probabilities often vary across life stages. Studies specifically aimed at assessing tree survival are unusual and so data initially designed for other purposes often need to be…

Populations and Evolution · Quantitative Biology 2015-02-02 Aristides Moustakas , Matthew R. Evans

Reaction-diffusion equations are widely used as the governing evolution equations for modeling many physical, chemical, and biological processes. Here we derive reaction-diffusion equations to model transport with reactions on a…

Statistical Mechanics · Physics 2020-09-16 E. Abad , C. N. Angstmann , B. I. Henry , A. V. McGann , F. Le Vot , S. B. Yuste

The focus of a survival study is partly on the distribution of survival times, and partly on the health or quality of life of patients while they live. Health varies over time, and survival is the most basic aspect of health, so the two…

Methodology · Statistics 2016-01-20 Walter Dempsey , Peter McCullagh

Stochastic biochemical and transport processes have various final outcomes, and they can be viewed as dynamic systems with multiple exits. Many current theoretical studies, however, typically consider only a single time scale for each…

Statistical Mechanics · Physics 2020-08-26 Golan Bel , Anton Zilman , Anatoly B. Kolomeisky

Using an artificial system of self-replicating strings, we show a correlation between the age of a genotype and its abundance that reflects a punctuated rather than gradual picture of evolution, as suggested long ago by Willis. In support…

adap-org · Physics 2008-02-03 C. Adami , C. T. Brown , M. Haggerty

We consider a globally coupled network of active (oscillatory) and inactive (non-oscillatory) oscillators with distributed-delay coupling. Conditions for aging transition, associated with suppression of oscillations, are derived for uniform…

Statistical Mechanics · Physics 2017-10-24 B. Rahman , K. B. Blyuss , Y. N. Kyrychko

We review the field of the glass transition, glassy dynamics and aging from a statistical mechanics perspective. We give a brief introduction to the subject and explain the main phenomenology encountered in glassy systems, with a particular…

Statistical Mechanics · Physics 2020-10-12 Francesco Arceri , François P. Landes , Ludovic Berthier , Giulio Biroli

We study a class of multi-species birth-and-death processes going almost surely to extinction and admitting a unique quasi-stationary distribution (qsd for short). When rescaled by $K$ and in the limit $K\to+\infty$, the realizations of…

Probability · Mathematics 2020-06-22 J. -R. Chazottes , P. Collet , S. Martínez , S. Méléard

There is sustained and widespread interest in understanding the limit, if any, to the human lifespan. Apart from its intrinsic and biological interest, changes in survival in old age have implications for the sustainability of social…

Applications · Statistics 2021-04-19 Léo R. Belzile , Anthony C. Davison , Jutta Gampe , Holger Rootzén , Dmitrii Zholud

We formulate a mathematical model of competition for resources between representatives of different age groups. A nonlinear kinetic integral-differential equation of the age aggression describes the process of redistribution of resources.…

Populations and Evolution · Quantitative Biology 2013-10-01 P. A. Golovinski

We use state-of-the-art molecular dynamics simulations to study hydrodynamic effects on aging during kinetics of phase separation in a fluid mixture. The domain growth law shows a crossover from a diffusive regime to a viscous hydrodynamic…

Statistical Mechanics · Physics 2015-06-12 Shaista Ahmad , Federico Corberi , Subir K. Das , Eugenio Lippiello , Sanjay Puri , Marco Zannetti

In this paper, we consider the relationship between phase-type distributions and positive systems through practical examples. Phase-type distributions, commonly used in modelling dynamic systems, represent the temporal evolution of a set of…

Methodology · Statistics 2024-08-20 Luz Judith Rodríguez Esparza , Fernando Baltazar Larios

General functions for human survival and mortality may support a possibility of general mechanisms in human ageing. We discovered that the survival and mortality curves could be described very simply and accurately by the Weibull survival…

Populations and Evolution · Quantitative Biology 2007-05-23 Byung Mook Weon

To describe the nonequilibrium states of a system we introduce a new thermodynamic parameter - the lifetime of a system. The statistical distributions which can be obtained out of the mesoscopic description characterizing the behaviour of a…

Statistical Mechanics · Physics 2007-05-23 V. V. Ryazanov

A method yielding simple relationships among bilateral birth-and-death processes is outlined. This allows one to relate birth and death rates of two processes in such a way that their transition probabilities, first-passage-time densities…

Probability · Mathematics 2008-03-11 Antonio Di Crescenzo