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The delimitation of biological species, i.e., deciding which individuals belong to the same species and whether and how many different species are represented in a data set, is key to the conservation of biodiversity. Much existing work…

Populations and Evolution · Quantitative Biology 2025-12-15 Gabriele d'Angella , Christian Hennig

Game theoretic tools are utilized to analyze a one-locus continuous selection model of sex-specific meiotic drive by considering nonequivalence of the viabilities of reciprocal heterozygotes that might be noticed at an imprinted locus. The…

Populations and Evolution · Quantitative Biology 2015-12-07 Bijan Sarkar

Nestedness is a property of interaction networks widely observed in natural mutualistic communities. Despite a widespread interest on this pattern, no general consensus exists on how to measure it. Instead, several metrics aiming at…

Physics and Society · Physics 2020-02-04 Claudia Payrato-Borras , Laura Hernandez , Yamir Moreno

Linear mixed models (LMMs) are a powerful and established tool for studying genotype-phenotype relationships. A limiting assumption of LMMs is that the residuals are Gaussian distributed, a requirement that rarely holds in practice.…

Genomics · Quantitative Biology 2014-08-10 Nicolo Fusi , Christoph Lippert , Neil D. Lawrence , Oliver Stegle

Assessing the quality of LLM-generated text remains a fundamental challenge in natural language processing. Current evaluation approaches often rely on isolated metrics or simplistic aggregations that fail to capture the nuanced trade-offs…

Computation and Language · Computer Science 2025-06-25 Esteban Garces Arias , Hannah Blocher , Julian Rodemann , Matthias Aßenmacher , Christoph Jansen

Motivation: Most existing methods for DNA sequence analysis rely on accurate sequences or genotypes. However, in applications of the next-generation sequencing (NGS), accurate genotypes may not be easily obtained (e.g. multi-sample…

Genomics · Quantitative Biology 2013-03-19 Heng Li

Deep Generative Models (DGMs) are versatile tools for learning data representations while adequately incorporating domain knowledge such as the specification of conditional probability distributions. Recently proposed DGMs tackle the…

Machine Learning · Computer Science 2024-01-30 Romain Lopez , Jan-Christian Huetter , Ehsan Hajiramezanali , Jonathan Pritchard , Aviv Regev

DNA-based biodiversity surveys involve collecting physical samples from survey sites and assaying the contents in the laboratory to detect species via their diagnostic DNA sequences. DNA-based surveys are increasingly being adopted for…

Graph generation is a crucial task in many fields, including network science and bioinformatics, as it enables the creation of synthetic graphs that mimic the properties of real-world networks for various applications. Graph Generative…

Machine Learning · Computer Science 2026-01-21 Salvatore Romano , Marco Grassia , Giuseppe Mangioni

Population diversity is essential for avoiding premature convergence in Genetic Algorithms (GAs) and for the effective use of crossover. Yet the dynamics of how diversity emerges in populations are not well understood. We use rigorous…

Neural and Evolutionary Computing · Computer Science 2016-08-11 Duc-Cuong Dang , Tobias Friedrich , Timo Kötzing , Martin S. Krejca , Per Kristian Lehre , Pietro S. Oliveto , Dirk Sudholt , Andrew M. Sutton

Clustering is a difficult and widely-studied data mining task, with many varieties of clustering algorithms proposed in the literature. Nearly all algorithms use a similarity measure such as a distance metric (e.g. Euclidean distance) to…

Neural and Evolutionary Computing · Computer Science 2019-10-24 Andrew Lensen , Bing Xue , Mengjie Zhang

Recent publications have described and applied a novel metric that quantifies the genetic distance of an individual with respect to two population samples, and have suggested that the metric makes it possible to infer the presence of an…

Genomics · Quantitative Biology 2015-09-24 Rosemary Braun , William Rowe , Carl Schaefer , Jinghui Zhang , Kenneth Buetow

Promoting and maintaining diversity of candidate solutions is a key requirement of evolutionary algorithms in general and multi-objective evolutionary algorithms in particular. In this paper, we use the recently developed theory of…

Neural and Evolutionary Computing · Computer Science 2023-03-15 Steve Huntsman

Graph generative models are a highly active branch of machine learning. Given the steady development of new models of ever-increasing complexity, it is necessary to provide a principled way to evaluate and compare them. In this paper, we…

Machine Learning · Computer Science 2022-03-21 Leslie O'Bray , Max Horn , Bastian Rieck , Karsten Borgwardt

Clustering algorithms are pivotal in data analysis, enabling the organization of data into meaningful groups. However, individual clustering methods often exhibit inherent limitations and biases, preventing the development of a universal…

Neural and Evolutionary Computing · Computer Science 2024-12-13 H. Jahani , F. Zamio

Diversity is essential for language-model applications ranging from creative generation to scientific discovery, yet modern LLMs often collapse into a narrow subset of plausible outputs. While prior work has developed benchmarks for…

We propose a metric which can be used to compute the amount of heritable variation enabled by a given dynamical system. A distribution of selection pressures is used such that each pressure selects a particular fixed point via competitive…

Populations and Evolution · Quantitative Biology 2017-02-08 Nicholas Guttenberg , Matthieu Laneuville , Melissa Ilardo , Nathanael Aubert-Kato

This paper applies the gradient discretisation method (GDM) for fourth order elliptic variational inequalities. The GDM provides a new formulation of error estimates and a complete convergence analysis of several numerical methods. We show…

Numerical Analysis · Mathematics 2023-05-31 Yahya Alnashri

Understanding and replicating the real world is a critical challenge in Artificial General Intelligence (AGI) research. To achieve this, many existing approaches, such as world models, aim to capture the fundamental principles governing the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Yuqi Hu , Longguang Wang , Xian Liu , Ling-Hao Chen , Yuwei Guo , Yukai Shi , Ce Liu , Anyi Rao , Zeyu Wang , Hui Xiong

While generative adversarial networks (GAN) are popular for their higher sample quality as opposed to other generative models like the variational autoencoders (VAE) and Boltzmann machines, they suffer from the same difficulty of the…

Machine Learning · Computer Science 2021-12-17 Harshvardhan GM , Aanchal Sahu , Mahendra Kumar Gourisaria
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