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We propose a mechanism of cell motility which is based on contraction and does not require protrusion. The contraction driven translocation of a cell is due to internal flow of the cytoskeleton generated by molecular motors. Each motor…

Biological Physics · Physics 2013-02-19 Pierre Recho , Thibault Putelat , Lev Truskinovsky

Polymerization of actin proteins into dynamic structures is essential to eukaryotic cell life. This has motivated a large body of in vitro experiments measuring polymerization kinetics of individual filaments. Here we model these kinetics,…

Biomolecules · Quantitative Biology 2009-11-10 Dimitrios Vavylonis , Qingbo Yang , Ben O'Shaughnessy

We analyze the effect of a gate on the conductance of molecules by separately evaluating the gate-induced polarization and the potential shift of the molecule relative to the leads. The calculations use ab initio density functional theory…

Materials Science · Physics 2007-05-23 San-Huang Ke , Harold U. Baranger , Weitao Yang

The selective insertion of foreign materials, such as fluorescent markers or plasmids, into living cells has been a challenging problem in cell biology.However, it is often necessary that researchers insert such materials into cells for…

Cell Behavior · Quantitative Biology 2016-02-26 Kamal Dhakal , Bryan Black , Samarendra Mohanty

Actin networks, acting as an engine pushing against an external load, are fundamentally important to cell motility. A measure of the effectiveness of an engine is the velocity the engine is able to produce at a given force, the…

Subcellular Processes · Quantitative Biology 2011-11-30 Daniel B. Smith , Jian Liu

We develop a formalism to describe the equilibrium distributions for segments of confined branched networks consisting of stiff filaments. This is applicable to certain situations of cytoskeleton in cells, such as for example actin…

Soft Condensed Matter · Physics 2019-02-21 Somiéalo Azote , Kristian K. Müller-Nedebock

It is well known that many biochemical processes in the cell such as gene regulation, growth signals and activation of ion channels, rely on mechanical stimuli. However, the mechanism by which mechanical signals propagate through cells is…

Soft Condensed Matter · Physics 2017-04-05 Adar Sonn-Segev , Anne Bernheim-Groswasser , Yael Roichman

We demonstrate a discrete implementation of a wave-based majority gate in a chaotic Life-like cellular automaton. The gate functions via controlling of patterns' propagation into stationary channels. The gate presented is realisable in many…

Emerging Technologies · Computer Science 2021-10-13 Genaro J. Martinez , Andrew Adamatzky , Shigeru Ninagawa , Kenichi Morita

Integrins mediate cell adhesion and are essential receptors for the development and functioning of multicellular organisms. Integrin activation is known to require both ligand and talin binding and to correlate with cluster formation but…

Molecular Networks · Quantitative Biology 2007-05-23 Dagmar Iber , Iain D Campbell

Eukaryotic cells can move spontaneously without being guided by external cues. For such spontaneous movements, a variety of different modes have been observed, including the amoeboid-like locomotion with protrusion of multiple pseudopods,…

Cell Behavior · Quantitative Biology 2009-03-16 Shin I. Nishimura , Masahiro Ueda , Masaki Sasai

The actin cytoskeleton is an active semi-flexible polymer network whose non-equilibrium properties coordinate both stable and contractile behaviors to maintain or change cell shape. While myosin motors drive the actin cytoskeleton…

The structural reorganization of the actin cytoskeleton is facilitated through the action of motor proteins that crosslink the actin filaments and transport them relative to each other. Here, we present a combined experimental-computational…

Biological Physics · Physics 2015-06-04 Daniel Gordon , Anne Bernheim-Groswasser , Chen Keasar , Oded Farago

The intrachannel interaction of pulses in weakly nonlinear coherent optical fiber lines is theoretically investigated. It is shown that the main contribution to the perturbation of the optical field comes from resonant interactions of…

Optics · Physics 2021-05-26 J. Gibney , I. A. Kuk , I. R. Gabitov

Inspired by recent experimental observation of patterning at the membrane of a living cell, we propose a generic model for the dynamics of a fluctuating interface driven by particle-like inclusions which stimulate its growth. We find that…

Soft Condensed Matter · Physics 2019-07-25 F. Cagnetta , M. R. Evans , D. Marenduzzo

The colloid cellular automata do not imitate the physical structure of colloids but are governed by logical functions derived from the colloids. We analyse the space-time complexity of Boolean circuits derived from the electrical responses…

The composite cytoskeleton, comprising interacting networks of semiflexible actin and rigid microtubules, actively generates forces and restructures using motor proteins such as myosins to enable key mechanical processes including cell…

Neural oscillations can enhance feature recognition, modulate interactions between neurons, and improve learning and memory. Simulational studies have shown that coherent oscillations give rise to windows in time during which information…

Neurons and Cognition · Quantitative Biology 2014-10-07 Andrew T. Sornborger , Louis Tao

We propose a novel mechanism of cell motility, which relies on the coupling of actin polymerization at the cell membrane to geometric confinement. We consider a polymerizing viscoelastic cytoskeletal gel confined in a narrow channel, and…

Soft Condensed Matter · Physics 2009-02-13 R. J. Hawkins , M. Piel , G. Faure-Andre , A. M. Lennon-Dumenil , J. F. Joanny , J. Prost , R. Voituriez

A classical logic gate connecting input and output light pulses is demonstrated. The gate operation is based on three steps: First, two incoming light pulses are stored in a Bose-Einstein condensate, second, atomic four-wave mixing…

Quantum Physics · Physics 2013-01-03 Christoph Vo , Stefan Riedl , Simon Baur , Gerhard Rempe , Stephan Dürr

In this work, we have investigated conduction through an artificial molecule comprising two coupled quantum dots. The question addressed is the role of inter-dot coupling on electronic transport. We find that the current through the…

Mesoscale and Nanoscale Physics · Physics 2011-09-22 M. Imran , B. Tariq , M. Tahir , K. Sabeeh
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