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Adaptive Molecular Resolution approaches in Molecular Dynamics are becoming relevant tools for the analysis of molecular liquids characterized by the interplay of different physical scales. The essential difference among these methods is in…

Computational Physics · Physics 2016-11-23 Jinglong Zhu , Rupert Klein , Luigi Delle Site

Molecular self-organization driven by concerted many-body interactions produces the ordered structures that define both inanimate and living matter. Understanding the physical mechanisms that govern the formation of molecular complexes and…

Chemical Physics · Physics 2023-07-21 Hendrik Jung , Roberto Covino , A Arjun , Peter G. Bolhuis , Gerhard Hummer

Active structures have the ability to change their shape, properties, and functionality as a response to changing operational conditions, which makes them more versatile than their static counterparts. However, most active structures…

Computational Engineering, Finance, and Science · Computer Science 2021-09-01 Thomas S. Lumpe , Michael Tao , Kristina Shea , David I. W. Levin

Modern computational chemistry has reached a stage at which massive exploration into chemical reaction space with unprecedented resolution with respect to the number of potentially relevant molecular structures has become possible. Various…

Chemical Physics · Physics 2020-04-27 Jan P. Unsleber , Markus Reiher

In this study of catalytic microfluidic reactors we show that, when optimally structured, these reactors share underlying scaling properties. The scaling is predicted theoretically and verified numerically. Furthermore, we show how to…

Fluid Dynamics · Physics 2007-05-23 Fridolin Okkels , Henrik Bruus

We demonstrate that autocatalytic reactions, where a product catalyzes its own formation, can be significantly accelerated when the product molecules are indistinguishable from each other. This ``combinatorial enhancement," analogous to the…

Statistical Mechanics · Physics 2025-03-19 Nanako Hirano , Akira Yoshida , Takenobu Nakamura , Naoko Nakagawa

In the combinatorial action model of contract design, a principal delegates a complex project to an agent, incentivizing a subset of actions from a ground set of $n$ actions, via a linear contract. Computing the optimal contract is a…

Computer Science and Game Theory · Computer Science 2026-04-17 Elizabeth Baldwin , Paul Duetting , Michal Feldman , Maya Schlesinger

In the present paper, an integrated paradigm for topology optimization on complex surfaces with arbitrary genus is proposed. The approach is constructed based on the two-dimensional (2D) Moving Morphable Component (MMC) framework, where a…

Optimization and Control · Mathematics 2022-02-03 Wendong Huo , Chang Liu , Zongliang Du , Xudong Jiang , Zhengyu Liu , Xu Guo

One of the main challenges in diffusion-based molecular communication is dealing with the non-linearity of reaction-diffusion chemical equations. While numerical methods can be used to solve these equations, a change in the input signals or…

Information Theory · Computer Science 2021-06-04 Hamidreza Abin , Amin Gohari , Masoumeh Nasiri-Kenari

Increasing interest in integrating advanced robotics within manufacturing has spurred a renewed concentration in developing real-time scheduling solutions to coordinate human-robot collaboration in this environment. Traditionally, the…

Robotics · Computer Science 2020-06-30 Zheyuan Wang , Matthew Gombolay

Stochastic simulation methods can be applied successfully to model exact spatio-temporally resolved reaction-diffusion systems. However, in many cases, these methods can quickly become extremely computationally intensive with increasing…

Quantitative Methods · Quantitative Biology 2016-04-29 Jonathan U. Harrison , Christian A. Yates

Multiphysics simulations play an essential role in accurately modeling complex interactions across diverse scientific and engineering domains Although neural operators especially the Fourier Neural Operator FNO have significantly improved…

Machine Learning · Computer Science 2025-09-23 Yifei Sun , Tao Wang , Junqi Qu , Yushun Dong , Hewei Tang , Shibo Li

Accurate low dimension chemical kinetic models for methane are an essential component in the design of efficient gas turbine combustors. Kinetic models coupled to computational fluid dynamics (CFD) provide quick and efficient ways to test…

Chemical Physics · Physics 2022-06-10 Mark Kelly , Gilles Bourque , Stephen Dooley

A macroscopic mesoscopic, deterministic stochastic coupling strategy is proposed to accelerate the direct simulation Monte Carlo (DSMC) method for chemical reaction. First, a macroscopic synthetic equation is formulated by integrating…

Computational Physics · Physics 2026-05-14 Hong Deng , Liyan Luo , Lei Wu

Intelligent agents working in real-world environments must be able to learn about the environment and its capabilities which enable them to take actions to change to the state of the world to complete a complex multi-step task in a…

Artificial Intelligence · Computer Science 2025-02-06 Rajesh Mangannavar

A typical goal of research in combinatorial optimization is to come up with fast algorithms that find optimal solutions to a computational problem. The process that takes a real-world problem and extracts a clean mathematical abstraction of…

Data Structures and Algorithms · Computer Science 2025-07-22 Sheikh Shakil Akhtar , Jayakrishnan Madathil , Pranabendu Misra , Geevarghese Philip

Computer models, aiming at simulating a complex real system, are often calibrated in the light of data to improve performance. Standard calibration methods assume that the optimal values of calibration parameters are invariant to the model…

Methodology · Statistics 2017-09-01 Georgios Karagiannis , Bledar A. Konomi , Guang Lin

In order to perceive the behavior presented by the multiphase chemical reactors, the ant colony optimization algorithm was combined with computational fluid dynamics (CFD) data. This intelligent algorithm creates a probabilistic technique…

Machine Learning · Computer Science 2020-01-14 Shahab Shamshirband , Meisam Babanezhad , Amir Mosavi , Narjes Nabipour , Eva Hajnal , Laszlo Nadai , Kwok-Wing Chau

Effective therapy of complex diseases requires control of highly non-linear complex networks that remain incompletely characterized. In particular, drug intervention can be seen as control of signaling in cellular networks. Identification…

Quantitative Methods · Quantitative Biology 2009-09-03 Jacob D. Feala , Jorge Cortes , Phillip M. Duxbury , Carlo Piermarocchi , Andrew D. McCulloch , Giovanni Paternostro

This paper presents a constrained adaptive dynamic programming (CADP) algorithm to solve general nonlinear nonaffine optimal control problems with known dynamics. Unlike previous ADP algorithms, it can directly deal with problems with state…

Systems and Control · Electrical Eng. & Systems 2022-04-11 Jingliang Duan , Zhengyu Liu , Shengbo Eben Li , Qi Sun , Zhenzhong Jia , Bo Cheng