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We demonstrate the feasibility of quantum computing for large-scale, realistic chemical systems through the development of a new interface using a quantum circuit simulator and CP2K, a highly efficient first-principles calculation software.…

Chemical Physics · Physics 2025-06-24 Tomoya Shiota , Klaas Gunst , Toshio Mori , Toru Shiozaki , Wataru Mizukami

Accurately predicting response properties of molecules such as the dynamic polarizability and hyperpolarizability using quantum mechanics has been a long-standing challenge with widespread applications in material and drug design. Classical…

Chemical Physics · Physics 2020-09-01 Xiaoxia Cai , Wei-Hai Fang , Heng Fan , Zhendong Li

The ever increasing demands placed upon machine performance have resulted in the need for more comprehensive particle accelerator modeling. Computer simulations are key to the success of particle accelerators. Many aspects of particle…

The angular momentum of molecules, or, equivalently, their rotation in three-dimensional space, is ideally suited for quantum control. Molecular angular momentum is naturally quantized, time evolution is governed by a well-known Hamiltonian…

Quantum Physics · Physics 2019-10-23 Christiane P. Koch , Mikhail Lemeshko , Dominique Sugny

This paper discusses how to implement certain classes of quantum computer algorithms using classical discrete switching networks that are amenable to implementation in main stream CMOS transistor IC technology. The methods differ from other…

Computational Complexity · Computer Science 2009-05-14 John S. Hamel

Optimally-shaped electromagnetic fields have the capacity to coherently control the dynamics of quantum systems and thus offer a promising means for controlling molecular transformations relevant to chemical, biological, and materials…

Quantum Physics · Physics 2021-06-08 Alicia B. Magann , Matthew D. Grace , Herschel A. Rabitz , Mohan Sarovar

Over the past decades, atomistic simulations of chemical, biological and materials systems have become increasingly precise and predictive thanks to the development of accurate and efficient techniques that describe the quantum mechanical…

Chemical Physics · Physics 2018-03-13 Thomas E. Markland , Michele Ceriotti

Quantum chemistry calculations on a quantum computer frequently suffer from symmetry breaking: the situation when a state of assumed spin and number of electrons is contaminated with contributions of undesired symmetry. The situation may…

Quantum Physics · Physics 2018-12-27 Ilya G. Ryabinkin , Scott N. Genin

We extend replica exchange simulation in two ways, and apply our approaches to biomolecules. The first generalization permits exchange simulation between models of differing resolution -- i.e., between detailed and coarse-grained models.…

Biomolecules · Quantitative Biology 2009-11-11 Edward Lyman , F. Marty Ytreberg , Daniel M. Zuckerman

Electromagnetic computations, where the wavelength is small in relation to the geometry of interest, become computationally demanding. In order to manage computations for realistic problems like electromagnetic scattering from aircraft, the…

Computational Engineering, Finance, and Science · Computer Science 2018-01-12 Afshin Zafari , Elisabeth Larsson , Marco Righero , M. Alessandro Francavilla , Giorgio Giordanengo , Francesca Vipiana , Giuseppe Vecchi

The exponential growth of the power of modern digital computers is based upon the miniaturisation of vast nanoscale arrays of electronic switches, but this will be eventually constrained by fabrication limits and power dissipation. Chemical…

Emerging Technologies · Computer Science 2022-04-29 Abhishek Sharma , Marcus Tze-Kiat Ng , Juan Manuel Parrilla Gutierrez , Yibin Jiang , Leroy Cronin

Model-based process simulation can be used to derive designs and operating conditions of chemical processes that optimally balance multiple objectives, such as quality, costs, or environmental impacts. This work focuses on identifying…

Ant colony optimization (ACO) is a commonly used meta-heuristic to solve complex combinatorial optimization problems like traveling salesman problem (TSP), vehicle routing problem (VRP), etc. However, classical ACO algorithms provide better…

Emerging Technologies · Computer Science 2021-11-05 Mrityunjay Ghosh , Nivedita Dey , Debdeep Mitra , Amlan Chakrabarti

The efficient exploration of chemical space to design molecules with intended properties enables the accelerated discovery of drugs, materials, and catalysts, and is one of the most important outstanding challenges in chemistry. Encouraged…

Computational Engineering, Finance, and Science · Computer Science 2023-10-12 AkshatKumar Nigam , Robert Pollice , Gary Tom , Kjell Jorner , John Willes , Luca A. Thiede , Anshul Kundaje , Alan Aspuru-Guzik

Quantum Reservoir Computing (QRC) harnesses quantum systems to tackle intricate computational problems with exceptional efficiency and minimized energy usage. This paper presents a QRC framework that utilizes a minimalistic quantum…

Quantum Physics · Physics 2025-11-11 Chuanzhou Zhu , Peter J. Ehlers , Hendra I. Nurdin , Daniel Soh

Chemical multisensor devices need calibration algorithms to estimate gas concentrations. Their possible adoption as indicative air quality measurements devices poses new challenges due to the need to operate in continuous monitoring modes…

Artificial Intelligence · Computer Science 2020-02-14 S. De Vito , E. Esposito , M. Salvato , O. Popoola , F. Formisano , R. Jones , G. Di Francia

The theory of stochastic processes impacts both physical and social sciences. At the molecular scale, stochastic dynamics is ubiquitous because of thermal fluctuations. The Fokker-Plank-Smoluchowski equation models the time evolution of the…

A method for integrating the chemical equations associated with nuclear combustion at high temperature is presented and extensively checked. Following the idea of E. M\"uller, the feedback between nuclear rates and temperature was taken…

Astrophysics · Physics 2007-05-23 Ruben M. Cabezon Gomez , Domingo Garcia-Senz , Eduardo Bravo

This paper will discuss the role of an artificially-intelligent computer system as critique-based, implicit-organizational, and an inherently necessary device, deployed in synchrony with parallel governmental policy, as a genuine means of…

Artificial Intelligence · Computer Science 2020-02-27 Christopher A. Tucker

A new method for quantum computation in the presence of detected spontaneous emission is proposed. The method combines strong and fast (dynamical decoupling) pulses and a quantum error correcting code that encodes $n$ logical qubits into…

Quantum Physics · Physics 2009-11-10 K. Khodjasteh , D. A. Lidar
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