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Background: Significance analysis plays a major role in identifying and ranking genes, transcription factor binding sites, DNA methylation regions, and other high-throughput features for association with disease. We propose a new approach,…

Methodology · Statistics 2017-01-10 Andrew E. Jaffe , John D. Storey , Hongkai Ji , Jeffrey T. Leek

Detecting variation in the evolutionary process along chromosomes is increasingly important as whole-genome data becomes more widely available. For example, factors such as incomplete lineage sorting, horizontal gene transfer, and…

Populations and Evolution · Quantitative Biology 2017-01-03 Elizabeth S. Allman , Laura S. Kubatko , John A. Rhodes

Despite the remarkable success of deep learning in medical imaging analysis, medical image segmentation remains challenging due to the scarcity of high-quality labeled images for supervision. Further, the significant domain gap between…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Hedda Cohen Indelman , Elay Dahan , Angeles M. Perez-Agosto , Carmit Shiran , Doron Shaked , Nati Daniel

Background: In the field of radiology and radiotherapy, accurate delineation of tissues and organs plays a crucial role in both diagnostics and therapeutics. While the gold standard remains expert-driven manual segmentation, many automatic…

Quantitative Methods · Quantitative Biology 2025-08-14 Szuzina Fazekas , Bettina Katalin Budai , Viktor Bérczi , Pál Maurovich-Horvat , Zsolt Vizi

Current successful approaches for generic (non-semantic) segmentation rely mostly on edge detection and have leveraged the strengths of deep learning mainly by improving the edge detection stage in the algorithmic pipeline. This is in…

Computer Vision and Pattern Recognition · Computer Science 2020-03-26 Or Isaacs , Oran Shayer , Michael Lindenbaum

Several image pattern recognition tasks rely on superpixel generation as a fundamental step. Image analysis based on superpixels facilitates domain-specific applications, also speeding up the overall processing time of the task. Recent…

Computer Vision and Pattern Recognition · Computer Science 2018-02-19 Marcelo Santos , Luciano Oliveira

Image segmentation plays a crucial role in extracting important objects of interest from images, enabling various applications. While existing methods have shown success in segmenting clean images, they often struggle to produce accurate…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Han Zhang , Daoping Zhang , Lok Ming Lui

In this study, we explore in depth a few under-studied topics at the intersection of uncertainty estimation and segmentation. Prior work has shown that the quality of uncertainty estimates can be very sensitive to a range of variables. As…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Michael Smith , Frank P. Ferrie

Internet of things (IoT) applications have become increasingly popular in recent years, with applications ranging from building energy monitoring to personal health tracking and activity recognition. In order to leverage these data,…

Machine Learning · Computer Science 2018-01-29 Wei-Han Lee , Jorge Ortiz , Bongjun Ko , Ruby Lee

Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

Although supervised deep-learning has achieved promising performance in medical image segmentation, many methods cannot generalize well on unseen data, limiting their real-world applicability. To address this problem, we propose a deep…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Recall one time when we were in an unfamiliar mall. We might mistakenly think that there exists or does not exist a piece of glass in front of us. Such mistakes will remind us to walk more safely and freely at the same or a similar place…

Computer Vision and Pattern Recognition · Computer Science 2023-04-24 Chengyu Zheng , Peng Li , Xiao-Ping Zhang , Xuequan Lu , Mingqiang Wei

Quantifying axon and myelin properties (e.g., axon diameter, myelin thickness, g-ratio) in histology images can provide useful information about microstructural changes caused by neurodegenerative diseases. Automatic tissue segmentation is…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Armand Collin , Arthur Boschet , Mathieu Boudreau , Julien Cohen-Adad

In response to the growing importance of geospatial data, its analysis including semantic segmentation becomes an increasingly popular task in computer vision today. Convolutional neural networks are powerful visual models that yield…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Alexey Bokhovkin , Evgeny Burnaev

This paper addresses the automatic image segmentation problem in a region merging style. With an initially over-segmented image, in which the many regions (or super-pixels) with homogeneous color are detected, image segmentation is…

Computer Vision and Pattern Recognition · Computer Science 2015-05-20 Bo Peng , Lei Zhang , David Zhang

In this paper we present an alternative method to symbolic segmentation: we approach symbolic segmentation as an algorithm selection problem. That is, let there be a set A of available algorithms for symbolic segmentation, a set of input…

Computer Vision and Pattern Recognition · Computer Science 2016-08-15 Martin Lukac , Kamila Abdiyeva , Michitaka Kameyama

Annotation of medical images, such as MRI and CT scans, is crucial for evaluating treatment efficacy and planning radiotherapy. However, the extensive workload of medical professionals limits their ability to annotate large image datasets,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Eichi Takaya , Shinnosuke Yamamoto

Segmentation, or the outlining of objects within images, is a critical step in the measurement and analysis of cells within microscopy images. While improvements continue to be made in tools that rely on classical methods for segmentation,…

Quantitative Methods · Quantitative Biology 2024-03-15 Nodar Gogoberidze , Beth A. Cimini

In the field of functional genomics, the analysis of gene expression profiles through Machine and Deep Learning is increasingly providing meaningful insight into a number of diseases. The paper proposes a novel algorithm to perform Feature…

Genomics · Quantitative Biology 2023-03-31 Carlo Adornetto , Gianluigi Greco

We propose an end-to-end learning framework for segmenting generic objects in videos. Our method learns to combine appearance and motion information to produce pixel level segmentation masks for all prominent objects in videos. We formulate…

Computer Vision and Pattern Recognition · Computer Science 2017-04-13 Suyog Dutt Jain , Bo Xiong , Kristen Grauman
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