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Adverse drug reactions (ADRs) are a major barrier to safe and effective pharmacotherapy and increasingly reflect higher order interactions between drugs, genetic background, and clinical phenotypes. Existing graph based approaches usually…

Quantitative Methods · Quantitative Biology 2025-12-02 Ze Cai , Haotian Tang , Shuai Gao , Binbin Zhou , Junhan Zhao , Jun Wen

Combination pharmacotherapy offers substantial therapeutic advantages but also poses substantial risks of adverse drug reactions (ADRs). The accurate prediction of ADRs with interpretable computational methods is crucial for clinical safety…

Machine Learning · Computer Science 2026-03-17 Y. Cheung

This paper explores whether the use of drug reviews and social media could be leveraged as potential alternative sources for pharmacovigilance of adverse drug reactions (ADRs). We examined the performance of BERT alongside two variants that…

Computation and Language · Computer Science 2020-04-21 Brent Biseda , Katie Mo

In this work, we present the first corpus for German Adverse Drug Reaction (ADR) detection in patient-generated content. The data consists of 4,169 binary annotated documents from a German patient forum, where users talk about health issues…

Computation and Language · Computer Science 2022-08-04 Lisa Raithel , Philippe Thomas , Roland Roller , Oliver Sapina , Sebastian Möller , Pierre Zweigenbaum

In the realm of cancer treatment, summarizing adverse drug events (ADEs) reported by patients using prescribed drugs is crucial for enhancing pharmacovigilance practices and improving drug-related decision-making. While the volume and…

Computation and Language · Computer Science 2025-05-08 Sofia Jamil , Aryan Dabad , Bollampalli Areen Reddy , Sriparna Saha , Rajiv Misra , Adil A. Shakur

Medical report generation is one of the most challenging tasks in medical image analysis. Although existing approaches have achieved promising results, they either require a predefined template database in order to retrieve sentences or…

Computation and Language · Computer Science 2021-06-14 Xingyi Yang , Muchao Ye , Quanzeng You , Fenglong Ma

The mining of adverse drug events (ADEs) is pivotal in pharmacovigilance, enhancing patient safety by identifying potential risks associated with medications, facilitating early detection of adverse events, and guiding regulatory…

Artificial Intelligence · Computer Science 2024-10-04 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Aman Chadha , Samrat Mondal

Adverse reaction caused by drugs is a potentially dangerous problem which may lead to mortality and morbidity in patients. Adverse Drug Event (ADE) extraction is a significant problem in biomedical research. We model ADE extraction as a…

Computation and Language · Computer Science 2018-01-03 Suriyadeepan Ramamoorthy , Selvakumar Murugan

Medical coding is essential for standardizing clinical data and communication but is often time-consuming and prone to errors. Traditional Natural Language Processing (NLP) methods struggle with automating coding due to the large label…

Deep learning-based drug response prediction (DRP) methods can accelerate the drug discovery process and reduce R\&D costs. Although the mainstream methods achieve high accuracy in predicting response regression values, the regression-aware…

Biomolecules · Quantitative Biology 2023-12-19 Kun Li , Wenbin Hu

Adverse Drug Reactions (ADRs) from psychiatric medications are the leading cause of hospitalizations among mental health patients. With healthcare systems and online communities facing limitations in resolving ADR-related issues, Large…

Adverse drug reactions considerably impact patient outcomes and healthcare costs in cancer therapy. Using artificial intelligence to predict adverse drug reactions in real time could revolutionize oncology treatment. This study aims to…

Quantitative Methods · Quantitative Biology 2025-05-21 Fatma Zahra Abdeldjouad , Menaouer Brahami , Mohammed Sabri

Over the recent years, the emergence of large language models (LLMs) has given rise to a proliferation of domain-specific models that are intended to reflect the particularities of linguistic context and content as a correlate of the…

Computation and Language · Computer Science 2024-02-20 Chris von Csefalvay

Drug side effects are a major global health concern, necessitating advanced methods for their accurate detection and analysis. While Large Language Models (LLMs) offer promising conversational interfaces, their inherent limitations,…

Information Retrieval · Computer Science 2025-07-21 Shad Nygren , Pinar Avci , Andre Daniels , Reza Rassol , Afshin Beheshti , Diego Galeano

Extracting meaningful drug-related information chunks, such as adverse drug events (ADE), is crucial for preventing morbidity and saving many lives. Most ADEs are reported via an unstructured conversation with the medical context, so…

Computation and Language · Computer Science 2023-08-16 Jie Yang , Soyeon Caren Han , Siqu Long , Josiah Poon , Goran Nenadic

Adverse drug reaction (ADR) is widely concerned for public health issue. In this study we propose an original approach to detect the ADRs using feature matrix and feature selection. The experiments are carried out on the drug Aspirin. Major…

Computational Engineering, Finance, and Science · Computer Science 2014-09-03 Yihui liu , Uwe Aickelin

Medication recommendation is an essential task of AI for healthcare. Existing works focused on recommending drug combinations for patients with complex health conditions solely based on their electronic health records. Thus, they have the…

Machine Learning · Computer Science 2022-07-20 Chaoqi Yang , Cao Xiao , Fenglong Ma , Lucas Glass , Jimeng Sun

Large language models (LLMs) are useful tools with the capacity for performing specific types of knowledge work at an effective scale. However, LLM deployments in high-risk and safety-critical domains pose unique challenges, notably the…

Computation and Language · Computer Science 2024-09-05 Joe B Hakim , Jeffery L Painter , Darmendra Ramcharran , Vijay Kara , Greg Powell , Paulina Sobczak , Chiho Sato , Andrew Bate , Andrew Beam

Sophisticated evasion tactics in malicious Android applications, combined with their intricate behavioral semantics, enable attackers to conceal malicious logic within legitimate functions, underscoring the critical need for robust and…

Software Engineering · Computer Science 2025-09-12 Guangyu Zhang , Xixuan Wang , Shiyu Sun , Peiyan Xiao , Kun Sun , Yanhai Xiong

In the era of Large Language Models (LLMs), given their remarkable text understanding and generation abilities, there is an unprecedented opportunity to develop new, LLM-based methods for trustworthy medical knowledge synthesis, extraction…

Computation and Language · Computer Science 2024-08-06 Jihye Choi , Nils Palumbo , Prasad Chalasani , Matthew M. Engelhard , Somesh Jha , Anivarya Kumar , David Page