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During the last decades, the global prevalence of dengue progressed dramatically. It is a disease that is now endemic in more than one hundred countries of Africa, America, Asia, and the Western Pacific. In this paper, we present a…

The relationship between epidemiology, mathematical modeling and computational tools allows to build and test theories on the development and battling of a disease. This PhD thesis is motivated by the study of epidemiological models applied…

Optimization and Control · Mathematics 2014-01-30 Helena Sofia Rodrigues

We present an application of optimal control theory to Dengue epidemics. This epidemiologic disease is an important theme in tropical countries due to the growing number of infected individuals. The dynamic model is described by a set of…

Optimization and Control · Mathematics 2010-08-27 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

Mathematical modelling can help to explain the nature and dynamics of infection transmissions, as well as support a policy for implementing those strategies that are most likely to bring public health and economic benefits. The paper…

Optimization and Control · Mathematics 2015-09-01 Roman Denysiuk , Cristiana J. Silva , Delfim F. M. Torres

A model with six mutually-exclusive compartments related to dengue is studied. Three vector control tools are considered: insecticides (larvicide and adulticide) and mechanical control. The basic reproduction number associated to the model…

Optimization and Control · Mathematics 2013-11-26 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

A model with six mutually-exclusive compartments related to Dengue disease is presented. In this model there are three vector control tools: insecticides (larvicide and adulticide) and mechanical control. The problem is studied using an…

Optimization and Control · Mathematics 2012-07-10 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

The incidence of Dengue epidemiologic disease has grown in recent decades. In this paper an application of optimal control in Dengue epidemics is presented. The mathematical model includes the dynamic of Dengue mosquito, the affected…

Optimization and Control · Mathematics 2010-09-03 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

A model for the transmission of dengue disease is presented. It consists of eight mutually-exclusive compartments representing the human and vector dynamics. It also includes a control parameter (insecticide) in order to fight the…

Optimization and Control · Mathematics 2010-09-23 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

Dengue is one of the most important infectious diseases in the world, in terms of death and economic cost. Hence, the modeling of dengue is of great importance to help us understand the dynamics disease, and interfering with its spreading…

Populations and Evolution · Quantitative Biology 2019-08-28 Sylvestre Aureliano Carvalho , Stella Olívia da Silva , Iraziet da Cunha Charret

Aedes aegypti is known as the responsible vector transmitting dengue flavivirus. Unavailability of medication to cure the transmission of the virus in the human blood becomes a global health issue in recent decades. World epidemiologists…

Populations and Evolution · Quantitative Biology 2017-12-04 Karunia Putra Wijaya , Thomas Goetz , Edy Soewono

Dengue is one of the major international public health concerns. Although progress is underway, developing a vaccine against the disease is challenging. Thus, the main approach to fight the disease is vector control. A model for the…

Optimization and Control · Mathematics 2015-03-19 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres , Alan Zinober

Dengue is a vector-borne disease transmitted from an infected human to an Aedes mosquito, during a blood-meal. Dengue is still a major public health problem. A model for the disease transmission is presented, composed by human and…

Optimization and Control · Mathematics 2016-10-18 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

Dengue transmission is shaped by the population dynamics of the Aedes aegypti mosquito, making vector control a central strategy for disease mitigation. The impact of interventions such as larvicide, adulticide, and breeding-site reduction…

Dynamical Systems · Mathematics 2026-05-13 Aram Vajdi , Lee W. Cohnstaedt , Caterina M. Scoglio , Heman Shakeri

In this paper we propose some mathematical models for the transmission of dengue using a system of reaction-diffusion equations. The mosquitoes are divided into infected, uninfected and aquatic subpopulations, while the humans, which are…

Analysis of PDEs · Mathematics 2018-11-21 Felipo Bacani , Stylianos Dimas , Igor Leite Freire , Norberto Anibal Maidana , Mariano Torrisi

A model for the transmission of dengue disease is presented. It consists of eight mutually-exclusive compartments representing the human and vector dynamics. It also includes a control parameter (adulticide spray) in order to combat the…

Optimization and Control · Mathematics 2010-07-01 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres , Alan Zinober

The model considers the human population, the adult mosquito population and the population of immature stages, which includes eggs, larvae and pupae. The model also considers the vertical transmission of dengue in the mosquitoes and the…

We apply optimal control theory to a tuberculosis model given by a system of ordinary differential equations. Optimal control strategies are proposed to minimize the cost of interventions, considering reinfection and post-exposure…

Optimization and Control · Mathematics 2013-07-15 Cristiana J. Silva , Delfim F. M. Torres

The emergence of mutant lineages within a viral species has become a public health problem, as the existing treatments and drugs are usually more effective on the original lineages than in the mutant ones. The following manuscript presents…

In this paper we propose two nonlinear models for the control of anthracnose disease. The first is an ordinary differential equation (ODE) model which represents the within-host evolution of the disease. The second includes spatial…

Optimization and Control · Mathematics 2014-06-17 David Fotsa , Elvis Houpa , David Békollé , Christopher Thron , Michel Ndoumbé

We present a SIR+ASI epidemic model to describe the interaction between human and dengue fever mosquito populations. A control strategy in the form of vaccination, to decrease the number of infected individuals, is used. An optimal control…

Optimization and Control · Mathematics 2011-09-19 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres
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