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Genomics has revolutionized biology, enabling the interrogation of whole transcriptomes, genome-wide binding sites for proteins, and many other molecular processes. However, individual genomic assays measure elements that interact in vivo…

Machine Learning · Statistics 2022-06-08 Sumanta Basu , Karl Kumbier , James B. Brown , Bin Yu

We propose Causal Interaction Trees for identifying subgroups of participants that have enhanced treatment effects using observational data. We extend the Classification and Regression Tree algorithm by using splitting criteria that focus…

Methodology · Statistics 2021-12-08 Jiabei Yang , Issa J. Dahabreh , Jon A. Steingrimsson

The problem of identifying the best answer among a collection of items having real-valued distribution is well-understood. Despite its practical relevance for many applications, fewer works have studied its extension when multiple and…

Machine Learning · Statistics 2024-11-08 Cyrille Kone , Marc Jourdan , Emilie Kaufmann

Classification is the task of assigning a new instance to one of a set of predefined categories based on the attributes of the instance. A classification tree is one of the most commonly used techniques in the area of classification. In…

Methodology · Statistics 2021-08-26 Abdulmajeed Atiah Alharbi , Frank P. A. Coolen , Tahani Coolen-Maturi

Many systems exhibit complex interactions between their components: some features or actions amplify each other's effects, others provide redundant information, and some contribute independently. We present a simple geometric method for…

Machine Learning · Computer Science 2025-12-15 Ahmad Shamail , Claire McWhite

Feature attributions are post-training analysis methods that assess how various input features of a machine learning model contribute to an output prediction. Their interpretation is straightforward when features act independently, but it…

Machine Learning · Computer Science 2026-01-29 Kurt Butler , Guanchao Feng , Petar Djuric

Learning feature interactions is crucial for click-through rate (CTR) prediction in recommender systems. In most existing deep learning models, feature interactions are either manually designed or simply enumerated. However, enumerating all…

Machine Learning · Computer Science 2020-07-06 Bin Liu , Chenxu Zhu , Guilin Li , Weinan Zhang , Jincai Lai , Ruiming Tang , Xiuqiang He , Zhenguo Li , Yong Yu

We present Probabilistic Structure Integration (PSI), a system for learning richly controllable and flexibly promptable world models from data. PSI consists of a three-step cycle. The first step, Probabilistic prediction, involves building…

Decision trees are widely used for non-linear modeling, as they capture interactions between predictors while producing inherently interpretable models. Despite their popularity, performing inference on the non-linear fit remains largely…

Methodology · Statistics 2026-04-14 Soham Bakshi , Snigdha Panigrahi

Transfer learning (TL) for high-dimensional regression (HDR) is an important problem in machine learning, particularly when dealing with limited sample size in the target task. However, there currently lacks a method to quantify the…

Machine Learning · Statistics 2025-04-28 Nguyen Vu Khai Tam , Cao Huyen My , Vo Nguyen Le Duy

High-dimensional feature selection is a central problem in a variety of application domains such as machine learning, image analysis, and genomics. In this paper, we propose graph-based tests as a useful basis for feature selection. We…

Methodology · Statistics 2024-08-13 Swarnadip Ghosh , Somabha Mukherjee , Divyansh Agarwal , Yichen He , Mingzhi Song , Xuejiao Pei

Click-through rate (CTR) prediction, which aims to predict the probability of a user clicking on an ad or an item, is critical to many online applications such as online advertising and recommender systems. The problem is very challenging…

Information Retrieval · Computer Science 2019-08-27 Weiping Song , Chence Shi , Zhiping Xiao , Zhijian Duan , Yewen Xu , Ming Zhang , Jian Tang

We introduce a novel interpretable tree based algorithm for prediction in a regression setting. Our motivation is to estimate the unknown regression function from a functional decomposition perspective in which the functional components…

Machine Learning · Statistics 2023-08-04 Munir Hiabu , Enno Mammen , Joseph T. Meyer

Simulation-based Bayesian inference (SBI) can be used to estimate the parameters of complex mechanistic models given observed model outputs without requiring access to explicit likelihood evaluations. A prime example for the application of…

Machine Learning · Computer Science 2022-11-28 Jonas Beck , Michael Deistler , Yves Bernaerts , Jakob Macke , Philipp Berens

It is becoming increasingly important for machine learning methods to make predictions that are interpretable as well as accurate. In many practical applications, it is of interest which features and feature interactions are relevant to the…

Machine Learning · Statistics 2016-02-09 Viktoriya Krakovna , Jiong Du , Jun S. Liu

Inferring higher-order interaction structure from observations of dynamics is a central challenge in complex systems, particularly when data are scarce, noisy, or concentrated in lower-dimensional regions of state space. We develop…

Physics and Society · Physics 2026-05-07 Katerina Tang , Vivek Srikrishnan , Jackson Kulik

Discovering statistically significant patterns from databases is an important challenging problem. The main obstacle of this problem is in the difficulty of taking into account the selection bias, i.e., the bias arising from the fact that…

Machine Learning · Statistics 2016-03-10 Shinya Suzumura , Kazuya Nakagawa , Mahito Sugiyama , Koji Tsuda , Ichiro Takeuchi

Feature selection is a process of choosing a subset of relevant features so that the quality of prediction models can be improved. An extensive body of work exists on information-theoretic feature selection, based on maximizing Mutual…

Machine Learning · Computer Science 2016-12-05 Jilin Wu , Soumyajit Gupta , Chandrajit Bajaj

Calculation of near-neighbor interactions among high dimensional, irregularly distributed data points is a fundamental task to many graph-based or kernel-based machine learning algorithms and applications. Such calculations, involving…

High-dimensional datasets depict a challenge for learning tasks in data mining and machine learning. Feature selection is an effective technique in dealing with dimensionality reduction. It is often an essential data processing step prior…

Machine Learning · Computer Science 2023-09-18 Gustavo Sosa-Cabrera , Santiago Gómez-Guerrero , Miguel García-Torres , Christian E. Schaerer