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The way to infer well-supported phylogenetic trees that precisely reflect the evolutionary process is a challenging task that completely depends on the way the related core genes have been found. In previous computational biology studies,…

Gene trees record the combination of gene level events, such as duplication, transfer and loss, and species level events, such as speciation and extinction. Gene tree-species tree reconciliation methods model these processes by drawing gene…

Populations and Evolution · Quantitative Biology 2013-06-11 Gergely J. Szöllősi , Wojciech Rosikiewicz , Bastien Boussau , Eric Tannier , Vincent Daubin

The amount of completely sequenced chloroplast genomes increases rapidly every day, leading to the possibility to build large scale phylogenetic trees of plant species. Considering a subset of close plant species defined according to their…

Artificial Intelligence · Computer Science 2015-04-21 Bassam AlKindy , Christophe Guyeux , Jean-François Couchot , Michel Salomon , Christian Parisod , Jacques M. Bahi

Phylogenetic networks are a generalization of phylogenetic trees to leaf-labeled directed acyclic graphs that represent ancestral relationships between species whose past includes non-tree-like events such as hybridization and horizontal…

Combinatorics · Mathematics 2021-04-13 Janosch Döcker , Simone Linz , Charles Semple

There are several tools available to infer phylogenetic trees, which depict the evolutionary relationships among biological entities such as viral and bacterial strains in infectious outbreaks, or cancerous cells in tumor progression trees.…

Data Structures and Algorithms · Computer Science 2023-12-22 António Pedro Branco , Cátia Vaz , Alexandre P. Francisco

We consider the problem of estimating species trees from unrooted gene tree topologies in the presence of incomplete lineage sorting, a common phenomenon that creates gene tree heterogeneity in multilocus datasets. One popular class of…

Populations and Evolution · Quantitative Biology 2018-12-21 Sebastien Roch

A multilabeled tree (or MUL-tree) is a rooted tree in which every leaf is labelled by an element from some set, but in which more than one leaf may be labelled by the same element of that set. In phylogenetics, such trees are used in…

Populations and Evolution · Quantitative Biology 2018-03-16 Manuel Lafond , Nadia El-Mabrouk , Katharina T. Huber , Vincent Moulton

One of the classical questions in evolutionary biology is how evolutionary processes are coupled at the gene and species level. With this motivation, we compare the topological properties (mainly the depth scaling, as a characterization of…

Populations and Evolution · Quantitative Biology 2011-07-26 E. Alejandro Herrada , Víctor M. Eguíluz , Emilio Hernández-García , Carlos M. Duarte

In phylogenetics, phylogenetic trees are rooted binary trees, whereas phylogenetic networks are rooted arbitrary acyclic digraphs. Edges are directed away from the root and leaves are uniquely labeled with taxa in phylogenetic networks. For…

Populations and Evolution · Quantitative Biology 2016-03-30 Andreas DM Gunawan , Bhaskar DasGupta , Louxin Zhang

BPEC is an R package for Bayesian Phylogeographic and Ecological Clustering which allows geographical, environmental and phenotypic measurements to be combined with DNA sequences in order to reveal clustered structure resulting from…

Applications · Statistics 2018-09-19 Ioanna Manolopoulou , Axel Hille , Brent Emerson

Most genes are part of larger families of evolutionary related genes. The history of gene families typically involves duplications and losses of genes as well as horizontal transfers into other organisms. The reconstruction of detailed gene…

Populations and Evolution · Quantitative Biology 2023-04-25 Marc Hellmuth , Peter F. Stadler

This paper explores hierarchical clustering in the case where pairs of points have dissimilarity scores (e.g. distances) as a part of the input. The recently introduced objective for points with dissimilarity scores results in every tree…

Machine Learning · Computer Science 2020-09-01 Benjamin Moseley , Yuyan Wang

We propose a new method for hierarchical clustering based on the optimisation of a cost function over trees of limited depth, and we derive a message--passing method that allows to solve it efficiently. The method and algorithm can be…

Disordered Systems and Neural Networks · Physics 2015-05-14 M. Bailly-Bechet , S. Bradde , A. Braunstein , A. Flaxman , L. Foini , R. Zecchina

Molecular phylogeny has focused mainly on improving models for the reconstruction of gene trees based on sequence alignments. Yet, most phylogeneticists seek to reveal the history of species. Although the histories of genes and species are…

Populations and Evolution · Quantitative Biology 2013-11-05 Gergely J. Szöllosi , Eric Tannier , Vincent Daubin , Bastien Boussau

Clustering high-dimensional datasets is hard because interpoint distances become less informative in high-dimensional spaces. We present a clustering algorithm that performs nonlinear dimensionality reduction and clustering jointly. The…

Machine Learning · Computer Science 2018-03-06 Sohil Atul Shah , Vladlen Koltun

Clustering is one of the widely used data mining techniques for medical diagnosis. Clustering can be considered as the most important unsupervised learning technique. Most of the clustering methods group data based on distance and few…

Machine Learning · Computer Science 2012-12-24 K. Dhanalakshmi , H. Hannah Inbarani

Modern phylogenetics research is often performed within a Bayesian framework, using sampling algorithms such as Markov chain Monte Carlo (MCMC) to approximate the posterior distribution. These algorithms require careful evaluation of the…

Comparative genetic studies of non-model organisms are transforming rapidly due to major advances in sequencing technology. A limiting factor in these studies has been the identification and screening of orthologous loci across an…

Populations and Evolution · Quantitative Biology 2017-03-28 Brian Tilston Smith , Michael G. Harvey , Brant C. Faircloth , Travis C. Glenn , Robb T. Brumfield

Lateral gene transfer (LGT) is a common mechanism of non-vertical evolution where genetic material is transferred between two more or less distantly related organisms. It is particularly common in bacteria where it contributes to adaptive…

Probability · Mathematics 2012-06-18 Sebastien Roch , Sagi Snir

Gene expression profiles are essential in identifying different cancer phenotypes. Clustering gene expression datasets can provide accurate identification of cancerous cell lines, but this task is challenging due to the small sample size…

Biological Physics · Physics 2023-05-30 Yuchen Wu , Luke Dicks , David J. Wales
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