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Electro-stimulation or modulation of deep brain regions is commonly used in clinical procedures for the treatment of several nervous system disorders. In particular, transcranial direct current stimulation (tDCS) is widely used as an…

Image and Video Processing · Electrical Eng. & Systems 2020-04-29 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Non-invasive brain stimulation, such as transcranial alternating current stimulation (tACS) provides a powerful tool to directly modulate brain oscillations that mediate complex cognitive processes. While the body of evidence about the…

Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural…

Objective: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique used to generate conduction currents in the head and disrupt brain functions. To rapidly evaluate the tDCS-induced current density in…

Quantitative Methods · Quantitative Biology 2022-10-07 Xiaofan Jia , Sadeed Bin Sayed , Nahian Ibn Hasan , Luis J. Gomez , Guang-Bin Huang , Abdulkadir C. Yucel

Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…

Medical Physics · Physics 2023-12-27 Max Koehler , Stefan Goetz

Background and Objective: Transcranial temporal interference stimulation (tTIS) is a promising non-invasive brain stimulation technique in which interference between electrical current fields extends the possibilities of electrical brain…

Numerical Analysis · Mathematics 2026-02-05 Santtu Söderholm , Maryam Samavaki , Sampsa Pursiainen

This study focuses on Multi-Channel Transcranial Electrical Stimulation, a non-invasive brain method for stimulating neuronal activity under the influence of low-intensity currents. We introduce mathematical formulation for finding a…

Optimization and Control · Mathematics 2022-06-06 Fernando Galaz Prieto , Atena Rezaei , Maryam Samavaki , Sampsa Pursiainen

The use of small amplitude electric currents delivered through the scalp, termed transcranial current stimulation (tCS, tDCS / tACS when using DC / AC currents) holds considerable promise for developing safe and effective treatments for…

Neurons and Cognition · Quantitative Biology 2024-10-10 Julien Modolo , Mengsen Zhang , Joan Duprez , Flavio Frohlich

Objective. Personalized transcranial electrical stimulation (tES) has gained growing attention due to the substantial inter-individual variability in brain anatomy and physiology. While previous reviews have discussed the physiological…

Neurons and Cognition · Quantitative Biology 2025-11-06 Mo Wang , Kexin Zheng , Yingyue Xin , Xiang Chen , Yiling Liu , Huichun Luo , Jingsheng Tang , Tifei Yuan , Hongkai Wen , Pengfei Wei , Quanying Liu

This numerical simulation study investigates solving the L1-norm fitted and regularized (L1-L1) linear programming (LP) problem to find a well-localized volumetric current density in transcranial electrical stimulation (tES), where a…

Optimization and Control · Mathematics 2022-09-26 F. Galaz Prieto , M. Samavaki , S. Pursiainen

For decades, focal non-invasive neuromodulation of deep brain regions has not been possible because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic…

Neurons and Cognition · Quantitative Biology 2025-12-17 Pierre Vassiliadis , Elena Beanato , Maximilian J. Wessel , Friedhelm C. Hummel

Transcranial magnetic stimulation (TMS) is a technique for noninvasively stimulating a brain area for therapeutic, rehabilitation treatments and neuroscience research. Despite our understanding of the physical principles and experimental…

Neurons and Cognition · Quantitative Biology 2020-12-30 Jose Gomez-Tames , Ilkka Laakso , Akimasa Hirata

Whether transcranial direct current stimulation (tDCS) benefits stroke rehabilitation remains unclear. To investigate how tDCS reorganizes brain circuitry, nineteen post-stroke patients underwent rehabilitation sessions with bi-hemispheric…

Our findings indicated that brain stimulation exerted no effect on the patients cognitive functions. The study outcome suggest that tDCS over primary motor cortex may be considered as a potential nonpharmochological treatment add-on in MG.…

High-definition transcranial direct current stimulation (HD-tDCS) dosing in children remains largely empirical, relying on one-size-fits-all protocols despite rapid developmental changes in head anatomy and tissue properties that strongly…

Quantitative Methods · Quantitative Biology 2025-12-02 Zeming Liu , Mo Wang , Xuanye Pan , Yuan Yang , Wilson Truccolo , Quanying Liu

Purpose: This study investigates the feasibility of transcutaneous interferential spinal cord stimulation (tISCS), a novel non-invasive neuromodulation method, using temporal interference to enhance focality and comfort in spinal cord…

The main objective of the electrical stimulation of the brain is to generate action potentials from the application of electromagnetic fields. Among the available techniques, transcranial electrical stimulation (TES) represents a popular…

Medical Physics · Physics 2015-11-09 Carlos G. Tarazona , Carlos E. Guerra , Laura Chávez , Sebastián Andrade

Acquisition of fine motor skills is a time-consuming process as it requires frequent repetitions. Transcranial electrical stimulation is a promising means of enhancing simple motor skill development via neuromodulatory mechanisms. Here, we…

We study a problem of designing ``robust'' external excitations for control and synchronization of an assembly of homotypic harmonic oscillators representing so-called theta neurons. The model of theta neurons (Theta model) captures, in…

Optimization and Control · Mathematics 2024-09-23 Roman Chertovskih , Nikolay Pogodaev , Maxim Staritsyn , Joaquim Da Silva Sewane , Antonio Pedro Aguiar

Running title: Frontoparietal anodal tDCS reduces ketamine-induced oscillopathies.Abstract: During the prodromal phase of schizophrenia with its complex and insidious clinical picture, electroencephalographic recordings detect widespread…

Neurons and Cognition · Quantitative Biology 2020-10-14 Caroline Lahogue , Didier Pinault
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