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Background: Alignment of biological sequences such as DNA, RNA or proteins is one of the most widely used tools in computational bioscience. All existing alignment algorithms rely on heuristic scoring schemes based on biological expertise.…

Genomics · Quantitative Biology 2008-10-27 Orion Penner , Peter Grassberger , Maya Paczuski

Quantum algorithms for scientific computing and their applications have been studied actively. In this paper, we propose a quantum algorithm for estimating the first eigenvalue of a differential operator $\mathcal{L}$ on $\mathbb{R}^d$ and…

Quantum Physics · Physics 2025-06-13 Koichi Miyamoto , Yuichiro Tada

Quantum algorithms and complexity have recently been studied not only for discrete, but also for some numerical problems. Most attention has been paid so far to the integration problem, for which a speed-up is shown by quantum computers…

Quantum Physics · Physics 2007-05-23 Boleslaw Kacewicz

Quantum phase estimation (QPE) is a central algorithmic primitive that estimates eigenvalues of a Hamiltonian up to precision $\epsilon$ in Heisenberg-limited time $T=\Theta(1/\epsilon)$. Standard gate-based implementations of QPE require…

Quantum Physics · Physics 2026-05-22 Alexander Schmidhuber , Seth Lloyd

Quantum annealing is a heuristic algorithm for searching the ground state of an Ising model. Heuristic algorithms aim to obtain near-optimal solutions with a reasonable computation time. Accordingly, many algorithms have so far been…

Quantum Physics · Physics 2022-11-09 Shuntaro Okada , Masayuki Ohzeki

We present classical and quantum algorithms based on spectral methods for a problem in tensor principal component analysis. The quantum algorithm achieves a quartic speedup while using exponentially smaller space than the fastest classical…

Quantum Physics · Physics 2020-03-04 M. B. Hastings

Quantum computers are emerging as a viable alternative to tackle certain computational problems that are challenging for classical computers. With the rapid development of quantum hardware such as those based on trapped ions, there is…

Quantum Physics · Physics 2023-02-07 Saikat Ray Majumder , Annarita Giani , Weiwei Shen , Bogdan Neculaes , Daiwei Zhu , Sonika Johri

Quantum algorithms are able to solve particular problems exponentially faster than conventional algorithms, when implemented on a quantum computer. However, all demonstrations to date have required already knowing the answer to construct…

Quantum Physics · Physics 2013-03-22 Xiao-Qi Zhou , Pruet Kalasuwan , Timothy C. Ralph , Jeremy L. O'Brien

We propose a hybrid classical-quantum digitized-counterdiabatic algorithm to tackle the protein folding problem on a tetrahedral lattice. Digitized-counterdiabatic quantum computing is a paradigm developed to compress quantum algorithms via…

Quantum Physics · Physics 2023-07-13 Pranav Chandarana , Narendra N. Hegade , Iraitz Montalban , Enrique Solano , Xi Chen

We present a quantum-dynamical framework for identifying structurally important residues in proteins based on continuous time quantum walks (CTQWs) on weighted residue interaction networks constructed from experimentally resolved…

Quantum Physics · Physics 2026-04-21 Shah Ishmam Mohtashim , Manas Sajjan , Sabre Kais

Sampling from complicated probability distributions is a hard computational problem arising in many fields, including statistical physics, optimization, and machine learning. Quantum computers have recently been used to sample from…

Quantum algorithms offer significant speedups over their classical counterparts for a variety of problems. The strongest arguments for this advantage are borne by algorithms for quantum search, quantum phase estimation, and Hamiltonian…

Quantum Physics · Physics 2021-12-14 John M. Martyn , Zane M. Rossi , Andrew K. Tan , Isaac L. Chuang

Quantum machine learning aims to release the prowess of quantum computing to improve machine learning methods. By combining quantum computing methods with classical neural network techniques we aim to foster an increase of performance in…

High Energy Physics - Phenomenology · Physics 2021-03-17 Andrew Blance , Michael Spannowsky

Quantum annealing (QA) has the potential to significantly improve solution quality and reduce time complexity in solving combinatorial optimization problems compared to classical optimization methods. However, due to the limited number of…

Quantum Physics · Physics 2025-04-09 Seongmin Kim , Sang-Woo Ahn , In-Saeng Suh , Alexander W. Dowling , Eungkyu Lee , Tengfei Luo

We apply quantum integration to elementary particle-physics processes. In particular, we look at scattering processes such as ${\rm e}^+{\rm e}^- \to q \bar q$ and ${\rm e}^+{\rm e}^- \to q \bar q' {\rm W}$. The corresponding probability…

High Energy Physics - Phenomenology · Physics 2022-06-10 Gabriele Agliardi , Michele Grossi , Mathieu Pellen , Enrico Prati

Quantum machine learning techniques have been proposed as a way to potentially enhance performance in machine learning applications. In this paper, we introduce two new quantum methods for neural networks. The first one is a quantum…

Hybrid quantum-classical optimization algorithms represent one of the most promising application for near-term quantum computers. In these algorithms the goal is to optimize an observable quantity with respect to some classical parameters,…

Quantum Physics · Physics 2021-01-27 Leonardo Banchi , Gavin E. Crooks

We study supervised learning algorithms in which a quantum device is used to perform a computational subroutine - either for prediction via probability estimation, or to compute a kernel via estimation of quantum states overlap. We design…

Quantum Physics · Physics 2021-07-07 Ulysse Chabaud , Damian Markham , Adel Sohbi

Motivated by near term quantum computing hardware limitations, combinatorial optimization problems that can be addressed by current quantum algorithms and noisy hardware with little or no overhead are used to probe capabilities of quantum…

Optimization and Control · Mathematics 2026-05-15 Elijah Pelofske , Andreas Bärtschi , Stephan Eidenbenz

We construct a hybrid quantum-classical approach for the $K$-Nearest Neighbour algorithm, where the information is embedded in a phase-distributed multimode coherent state with the assistance of a single photon. The task of finding the…

Quantum Physics · Physics 2024-04-19 Vivek Mehta , Francesco Petruccione , Utpal Roy
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