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Fluorescence microscopy has revolutionized biomedical research over the past three decades. Its high molecular specificity and unrivaled single molecule level sensitivity have enabled breakthroughs in a variety of research fields. For in…
Being complex-valued and low in signal-to-noise ratios, magnitude-based diffusion MRI is confounded by the noise-floor that falsely elevates signal magnitude and incurs bias to the commonly used diffusion indices, such as fractional…
The thin and flexible nature of optical fibres often makes them the ideal technology to view biological processes in-vivo, but current microendoscopic approaches are limited in spatial resolution. Here, we demonstrate a new route to high…
We devise a laser-controlled adaptive optical element which operates intracavity under high intensity radiation. This element substitutes a conventional mechanically deformable mirror and is free of critical heat-sensitive components and…
We demonstrate accurate phase measurement from low photon level interference data using a constrained optimization method that takes into account the expected redundancy in the unknown phase function. This approach is shown to have…
We demonstrate a simple scheme for high-resolution imaging of nanoplasmonic structures that basically removes most of the resolution limiting allowed light usually transmitted to the far field. This is achieved by implementing a Fourier…
We propose a photonic adaptive Least-Mean-Squares equalizer with an opto-electronic feedback loop to determine the updating of an optical Finite-Impulse-Response filter's weights, enabling dispersion compensation introduced by 30-km fiber…
Low-noise lasers are of central importance in a wide variety of applications, including high spectral-efficiency coherent communication protocols, distributed fibre sensing, and long distance coherent LiDAR. In addition to low phase noise,…
Image slicing is a powerful technique in astronomy. It allows the instrument designer to reduce the slit width of the spectrograph, increasing spectral resolving power whilst retaining throughput. Conventionally this is done using bulk…
Many optical systems use acousto-optics for fast steering of light. However, acousto-optic (AO) light diffraction permits manipulation and shaping of light fields in a much broader sense including holography. While acousto-optic devices…
Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…
A lensless digital holography enables wide-field microscopic imaging without the limitations imposed by optical lens performance. However, conventional holographic imaging often relies on magnifying optical systems to compensate for the low…
The polarization of light conveys unique information that can be exploited by crucial applications. The bulky and costly discrete optical components used in conventional polarimeters limit their broad adoption. A compact, low-cost…
High efficiency collection of photons emitted by a point source over a wide field-of-view (FoV) is crucial for many applications. Multi-scale optics over improved light collection by utilizing small optical components placed close to the…
Multimode fibers (MMFs) can transmit multiple guided modes simultaneously, making them a promising platform for high-resolution biomedical imaging, endoscopy and high-bandwidth optical communication. However, their complex modal behavior,…
We address the exploitation of an optical parametric oscillator (OPO) in the task of mitigating, at least partially, phase noise produced by phase diffusion. In particular, we analyze two scenarios where phase diffusion is typically…
Interferometric-based microscopies stand as powerful label-free approaches for monitoring and characterising chemical reactions and heterogeneous nanoparticle systems in real time with single particle sensitivity. Nevertheless, coherent…
We propose a method of spatial resolution enhancement in metrology (thermometry, magnetometry, pH estimation, and similar methods) with blinking fluorescent nanosensors by combining sensing with super-resolution optical fluctuation imaging…
Image processing has become a critical technology in a variety of science and engineering disciplines. While most image processing is performed digitally, optical analog processing has the advantages of being low-power and high-speed though…
In this work, we present a highly efficient quantitative phase imaging (QPI) approach using programmable annular LED illumination based on traditional bright-field microscope. As a new type of coded illumination, the LED array provides a…