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Deep-tissue optical imaging is a longstanding challenge limited by scattering. Both optical imaging and treatment can benefit from focusing light in deep tissue beyond one transport mean free path. Wavefront shaping based on time-reversed…

Optics · Physics 2020-12-09 Juze Zhang , Zijian Gao , Xiaopeng Yu , Peng Ge , Feng Gao , Fei Gao

Manipulating and focusing light deep inside biological tissue and tissue-like complex media has been desired for long yet considered challenging. One feasible strategy is through optical wavefront engineering, where the optical…

Focusing light into opaque random or scattering media such as biological tissue is a much sought-after goal for biomedical applications such as photodynamic therapy, optical manipulation, and photostimulation. However, focusing with…

Optics · Physics 2014-03-10 Jian Wei Tay , Puxiang Lai , Yuta Suzuki , Lihong V. Wang

Light scattering inhibits high-resolution optical imaging, manipulation and therapy deep inside biological tissue by preventing focusing. To form deep foci, wavefront-shaping and time-reversal techniques that break the optical diffusion…

Optics · Physics 2015-06-04 Cheng Ma , Fengbo Zhou , Yan Liu , Lihong V. Wang

Thanks to a Multiple Scattering Theory algorithm, we present a way to focus energy at the deep subwavelength scale, from the far-field, inside a cubic disordered bubble cloud by using broadband Time Reversal (TR). We show that the…

Soft Condensed Matter · Physics 2015-10-26 Maxime Lanoy , Romain Pierrat , Fabrice Lemoult , Mathias Fink , Valentin Leroy , Arnaud Tourin

Optical focusing through/inside scattering media, like multimode fiber and biological tissues, has significant impact in biomedicine yet considered challenging due to strong scattering nature of light. Previously, promising progress has…

Light scattering in inhomogeneous media induces wavefront distortions which pose an inherent limitation in many optical applications. Examples range from microscopy and nanosurgery to astronomy. In recent years, ongoing efforts have made…

Optics · Physics 2015-05-20 Ori Katz , Yaron Bromberg , Eran Small , Yaron Silberberg

The ability to steer light propagation inside scattering media has long been sought-after due to its potential widespread applications. To form optical foci inside scattering media, the only feasible strategy is to guide photons by using…

Optics · Physics 2014-04-30 Cheng Ma , Xiao Xu , Yan Liu , Lihong V. Wang

We present a new approach for spatiotemporal focusing through complex scattering media by wave front shaping. Using a nonlinear feedback signal to shape the incident pulsed wave front, we show that the limit of a spatiotemporal matched…

Light propagation in materials with microscopic inhomogeneities is affected by scattering. In scattering materials, such as powders, disordered metamaterials or biological tissue, multiple scattering on sub-wavelength particles makes light…

Disordered Systems and Neural Networks · Physics 2009-11-13 I. M. Vellekoop , A. P. Mosk

Imaging with optical resolution through highly scattering media is a long sought-after goal with important applications in deep tissue imaging. Although being the focus of numerous works, this goal was considered impractical until recently.…

Optics · Physics 2012-02-10 Ori Katz , Eran Small , Yaron Silberberg

Wavefront shaping has revolutionized imaging deep in scattering media, being able to spatially and temporally refocus light through or inside the medium. However, wavefront shaping is not compatible yet with polarization-resolved microscopy…

Optics · Physics 2018-11-26 Hilton B. de Aguiar , Sylvain Gigan , Sophie Brasselet

Optical wavefront-shaping has emerged as a powerful tool to manipulate light in strongly scattering media. It enables diffraction-limited focusing and imaging at depths where conventional microscopy techniques fail. However, while most…

Optics · Physics 2014-03-04 T. Chaigne , O. Katz , A. C. Boccara , M. Fink , E. Bossy , S. Gigan

This thesis describes experimental work on the use of wavefront shaping to steer light through strongly scattering materials. We find that scattering does not irreversibly scramble the incident wave. By shaping the incident wavefront, we…

Optics · Physics 2008-07-08 I. M. Vellekoop

Optical time-reversal techniques are being actively developed to focus light through or inside opaque scattering media. When applied to biological tissue, these techniques promise to revolutionize biophotonics by enabling deep-tissue…

Biological Physics · Physics 2016-11-07 Yuecheng Shen , Yan Liu , Cheng Ma , Lihong V. Wang

Non-invasive optical focusing inside scattering media is still a big challenge because inhomogeneous media scatter both incoming photons for focusing and outgoing photons for observation. Various approaches, utilizing non-linear…

Optics · Physics 2021-09-17 Dayan Li , Sujit Kumar Sahoo , Huy Quoc Lam , Dong Wang , Cuong Dang

The efficient delivery of light energy is a prerequisite for non-invasive imaging and stimulating of target objects embedded deep within a scattering medium. However, injected waves experience random diffusion by multiple light scattering,…

Optical imaging deep inside scattering media remains a fundamental problem in bio-imaging. While wavefront shaping has been shown to allow focusing of coherent light at depth, achieving it non-invasively remains a challenge. Various…

Optics · Physics 2019-12-24 Antoine Boniface , Baptiste Blochet , Jonathan Dong , Sylvain Gigan

Scattering has usually be considered as detrimental for optical focusing or imaging. Recently, more and more research has shown that strongly scattering materials can be utilized to focus coherent light by controlling or shaping the…

Optics · Physics 2017-05-24 Yanqi Qiao , Xianfeng Chen , Yajun Peng , Yuanlin Zheng

We study theoretically light focusing at subwavelength scale inside a disordered strongly scattering open medium. We show that broadband time reversal at a single point antenna, in conjunction with near-field interactions and multiple…

Optics · Physics 2015-06-12 Romain Pierrat , Cédric Vandenbem , Mathias Fink , Rémi Carminati
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