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Motivation: Storage of genomic data is a major cost for the Life Sciences, effectively addressed mostly via specialized data compression methods. For the same reasons of abundance in data production, the use of Big Data technologies is seen…
Genome sequence analysis, which examines the DNA sequences of organisms, drives advances in many critical medical and biotechnological fields. Given its importance and the exponentially growing volumes of genomic sequence data, there are…
As large language models (LLMs) proliferate in scale, specialization, and latency profiles, the challenge of routing user prompts to the most appropriate model has become increasingly critical for balancing performance and cost. We…
Storing and archiving data produced by next-generation sequencing (NGS) is a huge burden for research institutions. Reference-based compression algorithms are effective in dealing with these data. Our work focuses on compressing FASTQ…
Motivation: Next Generation Sequencing technologies revolutionized many fields in biology by enabling the fast and cheap sequencing of large amounts of genomic data. The ever increasing sequencing capacities enabled by current sequencing…
Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to…
Minimizing data storage poses a significant challenge in large-scale metagenomic projects. In this paper, we present a new method for improving the encoding of FASTQ files generated by metagenomic sequencing. This method incorporates…
We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…
Current research on DNA storage usually focuses on the improvement of storage density by developing effective encoding and decoding schemes while lacking the consideration on the uncertainty in ultra-long-term data storage and retention.…
Motivation: Despite significant advances in Third-Generation Sequencing (TGS) technologies, Next-Generation Sequencing (NGS) technologies remain dominant in the current sequencing market. This is due to the lower error rates and richer…
The fall of prices of the high-throughput genome sequencing changes the landscape of modern genomics. A number of large scale projects aimed at sequencing many human genomes are in progress. Genome sequencing also becomes an important aid…
Smart shipping operations increasingly depend on collaborative AI, yet the underlying data are generated across vessels with uneven connectivity, limited backhaul, and clear commercial sensitivity. In such settings, server-coordinated FL…
With the development of gene sequencing technology, an explosive growth of gene data has been witnessed. And the storage of gene data has become an important issue. Traditional gene data compression methods rely on general software like…
Motivation: High-coverage sequencing data have significant, yet hard to exploit, redundancy. Most FASTQ compressors cannot efficiently compress the DNA stream of large datasets, since the redundancy between overlapping reads cannot be…
Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…
With growing interest in sustainable logistics, electric vehicle (EV)-based deliveries offer a promising alternative for urban distribution. However, EVs face challenges due to their limited battery capacity, requiring careful planning for…
Current network data telemetry pipelines consist of massive streams of fine-grained Key Performance Indicators (KPIs) from multiple distributed sources towards central aggregators, making data storage, transmission, and real-time analysis…
The rapid growth of digital data has heightened the demand for efficient lossless compression methods. However, existing algorithms exhibit trade-offs: some achieve high compression ratios, others excel in encoding or decoding speed, and…
DNA sequencing, especially of microbial genomes and metagenomes, has been at the core of recent research advances in large-scale comparative genomics. The data deluge has resulted in exponential growth in genomic datasets over the past…
Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by integrating external knowledge, leading to improved accuracy and relevance. However, scaling RAG pipelines remains computationally expensive as retrieval sizes…