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The bioinformatical methods to detect lateral gene transfer events are mainly based on functional coding DNA characteristics. In this paper, we propose the use of DNA traits not depending on protein coding requirements. We introduce several…

Neural and Evolutionary Computing · Computer Science 2012-04-13 C. Calderón , L. Delaye , V. Mireles , P. Miramontes

With the increasing inference cost of machine learning models, there is a growing interest in models with fast and efficient inference. Recently, an approach for learning logic gate networks directly via a differentiable relaxation was…

Machine Learning · Computer Science 2024-11-08 Felix Petersen , Hilde Kuehne , Christian Borgelt , Julian Welzel , Stefano Ermon

Recent advances in next-generation sequencing technologies have facilitated the use of deoxyribonucleic acid (DNA) as a novel covert channels in steganography. There are various methods that exist in other domains to detect hidden messages…

Machine Learning · Computer Science 2018-10-08 Ho Bae , Byunghan Lee , Sunyoung Kwon , Sungroh Yoon

Latent Dirichlet Allocation (LDA) is a three-level hierarchical Bayesian model for topic inference. In spite of its great success, inferring the latent topic distribution with LDA is time-consuming. Motivated by the transfer learning…

Machine Learning · Computer Science 2015-08-06 Dongxu Zhang , Tianyi Luo , Dong Wang , Rong Liu

Abstract reasoning, i.e., inferring complicated patterns from given observations, is a central building block of artificial general intelligence. While humans find the answer by either eliminating wrong candidates or first constructing the…

Machine Learning · Computer Science 2021-08-12 Sihyun Yu , Sangwoo Mo , Sungsoo Ahn , Jinwoo Shin

A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of…

Soft Condensed Matter · Physics 2015-06-25 Johan Lagerqvist , Michael Zwolak , Massimiliano Di Ventra

Deoxyribonucleic acid (DNA) has shown great promise in enabling computational applications, most notably in the fields of DNA digital data storage and DNA computing. Information is encoded as DNA strands, which will naturally bind in…

Machine Learning · Computer Science 2021-10-22 David Buterez

Charge transfer in a DNA duplex chain is studied by constructing a system with virtual electrodes connected at the ends of each DNA strand. The systeym is described by the tight-binding model and its transport is analyzed by the transfer…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 X. F. Wang , Tapash Chakraborty

In this paper, we propose a novel inference method for dynamic genetic networks which makes it possible to face with a number of time measurements n much smaller than the number of genes p. The approach is based on the concept of low order…

Statistics Theory · Mathematics 2009-05-29 Sophie Lèbre

LogicWeb has traditionally lacked devices for dealing with intractable queries. We address this limitation by adopting length-bounded inference, a form of approximate reasoning. A length-bounded inference is of the form $prov(P,G,n)$ which…

Logic in Computer Science · Computer Science 2017-10-19 Keehang Kwon , Daeseong Kang

The differentiable implementation of logic yields a seamless combination of symbolic reasoning and deep neural networks. Recent research, which has developed a differentiable framework to learn logic programs from examples, can even acquire…

Artificial Intelligence · Computer Science 2021-03-03 Hikaru Shindo , Masaaki Nishino , Akihiro Yamamoto

DNA has immense potential as an emerging data storage medium. The principle of DNA storage is the conversion and flow of digital information between binary code stream, quaternary base, and actual DNA fragments. This process will inevitably…

Information Retrieval · Computer Science 2022-10-21 Yun Qin , Fei Zhu , Bo Xi

Large Language Models (LLMs) have transformed natural language processing and hold growing promise for advancing science, healthcare, and decision-making. Yet their training paradigms remain dominated by affirmation-based inference, akin to…

Artificial Intelligence · Computer Science 2025-12-05 Peter B. Walker , Hannah Davidson , Aiden Foster , Matthew Lienert , Thomas Pardue , Dale Russell

DNA strand displacement is a key reaction in DNA homologous recombination and DNA mismatch repair and is also heavily utilized in DNA-based computation and locomotion. Despite its ubiquity in science and engineering, sequence-dependent…

Biological Physics · Physics 2016-04-13 Bo Broadwater , Harold Kim

Recent progress in large language models has renewed interest in how multi-step reasoning is represented internally. While prior work often treats reasoning as a linear chain, many reasoning problems are more naturally modeled as directed…

Computation and Language · Computer Science 2026-04-07 Tianjun Zhong , Linyang He , Nima Mesgarani

We propose a novel learning paradigm for Deep Neural Networks (DNN) by using Boolean logic algebra. We first present the basic differentiable operators of a Boolean system such as conjunction, disjunction and exclusive-OR and show how these…

Machine Learning · Computer Science 2019-04-10 Ali Payani , Faramarz Fekri

Deep neural networks are revolutionizing the way complex systems are developed. However, these automatically-generated networks are opaque to humans, making it difficult to reason about them and guarantee their correctness. Here, we propose…

Artificial Intelligence · Computer Science 2020-08-11 Yuval Jacoby , Clark Barrett , Guy Katz

The behavior of LLMs does not depend solely on the model itself. Components of the inference system, such as the inference engine, attention backend, and hardware platform, subtly influence how inputs are processed. These components differ…

Cryptography and Security · Computer Science 2026-05-29 Anna Wimbauer , Jonas Möller , Erik Imgrund , Konrad Rieck

Neural Networks sequentially build high-level features through their successive layers. We propose here a new neural network model where each layer is associated with a set of candidate mappings. When an input is processed, at each layer,…

Machine Learning · Computer Science 2014-10-03 Ludovic Denoyer , Patrick Gallinari

Conventional deep reinforcement learning methods are sample-inefficient and usually require a large number of training trials before convergence. Since such methods operate on an unconstrained action set, they can lead to useless actions. A…

Artificial Intelligence · Computer Science 2021-03-04 Daiki Kimura , Subhajit Chaudhury , Akifumi Wachi , Ryosuke Kohita , Asim Munawar , Michiaki Tatsubori , Alexander Gray