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Interference arises when the treatment assigned to one individual affects the outcomes of other individuals. Commonly, individuals are naturally grouped into clusters, and interference occurs only among individuals within the same cluster,…

Methodology · Statistics 2026-04-15 Chao Cheng , Fan Li

Investigators often use multi-source data (e.g., multi-center trials, meta-analyses of randomized trials, pooled analyses of observational cohorts) to learn about the effects of interventions in subgroups of some well-defined target…

Methodology · Statistics 2024-02-06 Guanbo Wang , Alexander Levis , Jon Steingrimsson , Issa Dahabreh

Inferring causal effects of treatments is a central goal in many disciplines. The potential outcomes framework is a main statistical approach to causal inference, in which a causal effect is defined as a comparison of the potential outcomes…

Methodology · Statistics 2018-01-04 Peng Ding , Fan Li

Causal inference (CI) in observational studies has received a lot of attention in healthcare, education, ad attribution, policy evaluation, etc. Confounding is a typical hazard, where the context affects both, the treatment assignment and…

Methodology · Statistics 2021-08-17 Ankit Sharma , Garima Gupta , Ranjitha Prasad , Arnab Chatterjee , Lovekesh Vig , Gautam Shroff

A data science task can be deemed as making sense of the data or testing a hypothesis about it. The conclusions inferred from data can greatly guide us to make informative decisions. Big data has enabled us to carry out countless prediction…

Machine Learning · Computer Science 2022-01-12 Wenhao Zhang , Ramin Ramezani , Arash Naeim

In estimating the effects of a treatment/policy with a network, an unit is subject to two types of treatment: one is the direct treatment on the unit itself, and the other is the indirect treatment (i.e., network/spillover influence)…

Methodology · Statistics 2025-06-16 Myoung-jae Lee

Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects…

Methodology · Statistics 2024-04-23 Kosuke Imai , Michael Lingzhi Li

Identifying covariates that modify treatment effects is a central problem in causal inference. Yet existing data-adaptive procedures do not provide finite-sample control over the expected number of false discoveries, risking spurious…

Methodology · Statistics 2026-05-12 Falco J. Bargagli-Stoffi , Omar Melikechi

We develop new algorithms for estimating heterogeneous treatment effects, combining recent developments in transfer learning for neural networks with insights from the causal inference literature. By taking advantage of transfer learning,…

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

Artificial Intelligence · Computer Science 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

Meta-analysis can be a critical part of the research process, often serving as the primary analysis on which the practitioners, policymakers, and individuals base their decisions. However, current literature synthesis approaches to…

Methodology · Statistics 2023-08-28 Lily H. Zhang , Menelaos Konstantinidis , Marie-Abèle Bind , Donald B. Rubin

When making treatment selection decisions, it is essential to include a causal effect estimation analysis to compare potential outcomes under different treatments or controls, assisting in optimal selection. However, merely estimating…

Machine Learning · Statistics 2024-10-08 Sherly Alfonso-Sánchez , Kristina P. Sendova , Cristián Bravo

Identifying causal treatment (or exposure) effects in observational studies requires the data to satisfy the unconfoundedness assumption which is not testable using the observed data. With sensitivity analysis, one can determine how the…

Methodology · Statistics 2023-01-31 Yang Ou , Lu Tang , Chung-Chou H. Chang

We consider causal inference in the presence of unobserved confounding. We study the case where a proxy is available for the unobserved confounding in the form of a network connecting the units. For example, the link structure of a social…

Machine Learning · Statistics 2019-06-03 Victor Veitch , Yixin Wang , David M. Blei

Our aging population increasingly suffers from multiple chronic diseases simultaneously, necessitating the comprehensive treatment of these conditions. Finding the optimal set of drugs for a combinatorial set of diseases is a combinatorial…

Artificial Intelligence · Computer Science 2016-11-16 Pranjul Yadav , Lisiane Prunelli , Alexander Hoff , Michael Steinbach , Bonnie Westra , Vipin Kumar , Gyorgy Simon

Methods for inferring average causal effects have traditionally relied on two key assumptions: (i) the intervention received by one unit cannot causally influence the outcome of another; and (ii) units can be organized into non-overlapping…

Methodology · Statistics 2019-08-23 Eric J. Tchetgen Tchetgen , Isabel Fulcher , Ilya Shpitser

We address the problem of using observational data to estimate peer contagion effects, the influence of treatments applied to individuals in a network on the outcomes of their neighbors. A main challenge to such estimation is that homophily…

Social and Information Networks · Computer Science 2022-05-18 Irina Cristali , Victor Veitch

This review systematizes the emerging literature for causal inference using deep neural networks under the potential outcomes framework. It provides an intuitive introduction on how deep learning can be used to estimate/predict…

Machine Learning · Computer Science 2023-11-30 Bernard Koch , Tim Sainburg , Pablo Geraldo , Song Jiang , Yizhou Sun , Jacob Gates Foster

In Bayesian meta-analysis, the specification of prior probabilities for the between-study heterogeneity is commonly required, and is of particular benefit in situations where only few studies are included. Among the considerations in the…

Methodology · Statistics 2023-06-02 Christian Röver , Sibylle Sturtz , Jona Lilienthal , Ralf Bender , Tim Friede

Over the past few decades, statistical methods for causal inference have made impressive strides, enabling progress across a range of scientific fields. However, much of this methodological development has been confined to individual…

Methodology · Statistics 2025-09-30 Wenqi Shi , José R. Zubizarreta
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