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We propose a method to reconstruct the density of an optical source in a highly scattering medium from ultrasound-modulated optical measurements. Our approach is based on the solution to a hybrid inverse source problem for the radiative…

Analysis of PDEs · Mathematics 2015-06-23 Guillaume Bal , Francis J. Chung , John C. Schotland

The inverse scattering problem from the multi-frequency backscattering data is a long-standing open problem. We advance the theory by proving a local uniqueness result. Moreover, we introduce a direct sampling method for quantitatively…

Numerical Analysis · Mathematics 2026-04-29 Yukun Guo , Xiaodong Liu

We investigate the inverse source problem for the wave equation, arising in photo- and thermoacoustic tomography. There exist quite a few theoretically exact inversion formulas explicitly expressing solution of this problem in terms of the…

Analysis of PDEs · Mathematics 2018-08-01 Ngoc Do , Leonid Kunyansky

Photoacoustic computed tomography (PACT) combines the optical contrast of optical imaging and the penetrability of sonography. In this work, we develop a novel PACT system to provide real-time imaging, which is achieved by a 120-elements…

Image and Video Processing · Electrical Eng. & Systems 2021-05-10 Hengrong Lan , Daohuai Jiang , Feng Gao , Fei Gao

Photoacoustic Computed Tomography (PACT) is a major configuration of photoacoustic imaging, a hybrid noninvasive modality for both functional and molecular imaging. PACT has rapidly gained importance in the field of biomedical imaging due…

Diffraction tomography is a widely used inverse scattering technique for quantitative imaging of weakly scattering media. In its conventional formulation, diffraction tomography assumes monochromatic plane wave illumination. This…

Numerical Analysis · Mathematics 2026-03-11 Peter Elbau , Noemi Naujoks , Otmar Scherzer

In this paper, we study the mathematical imaging problem of optical diffraction tomography (ODT) for the scenario of a microscopic rigid particle rotating in a trap created, for instance, by acoustic or optical forces. Under the influence…

Several novel imaging and non-destructive testing technologies are based on reconstructing the spatially dependent coefficient in an elliptic partial differential equation from measurements of its solution(s). In practical applications, the…

Numerical Analysis · Mathematics 2021-08-27 Bastian Harrach

Fourier ptychographic microscopy (FPM) is a recently developed imaging modality that uses angularly varying illumination to extend a system performance beyond the limit defined by its optical elements. The FPM technique applies a novel…

Optics · Physics 2014-05-02 Xiaoze Ou , Roarke Horstmeyer , Changhuei Yang , Guoan Zheng

Background: Photoacoustic Microscopy (PAM) integrates optical and acoustic imaging, offering enhanced penetration depth for detecting optical-absorbing components in tissues. Nonetheless, challenges arise in scanning large areas with high…

Medical Physics · Physics 2023-12-15 Irem Loc , Mehmet Burcin Unlu

We study the use of a learned forward operator in the inverse problem of photoacoustic tomography. The Fourier neural operator to approximate the photoacoustic wave propagation is used. Further, the inverse problem is solved using a…

Computational Physics · Physics 2026-03-24 Karoliina Puronhaara , Teemu Sahlström , Andreas Hauptmann , Tanja Tarvainen

The article deals with a classical inverse problem: the computation of the refractive index of a medium from ultrasound time-of-flight (TOF) measurements. This problem is very popular in seismics but also for tomographic problems in…

Numerical Analysis · Mathematics 2016-08-03 Udo Schroeder , Thomas Schuster

The inversion of linear systems is a fundamental step in many inverse problems. Computational challenges exist when trying to invert large linear systems, where limited computing resources mean that only part of the system can be kept in…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-09-05 Yushan Gao , Thomas Blumensath

Fluorescence spectroscopy and modeling provide powerful means to characterize biomacromolecular structures, dynamics, and interactions. F\"orster resonance energy transfer serves as a key technique for this due to its nanometer-scale…

Biological Physics · Physics 2026-02-26 Thomas-Otavio Peulen , Daria Maksutova , Thorben Cordes

Recently we demonstrated an integrated photoacoustic (PA) and ultrasound (PAUS) system using a kHz-rate wavelength-tunable laser and a swept-beam delivery approach. It irradiates a medium using a narrow laser beam sweeping at high…

Signal Processing · Electrical Eng. & Systems 2020-01-28 MinWoo Kim , Geng-Shi Jeng , Matthew O'Donnell , Ivan Pelivanov

Exterior inverse problem for the circular means transform (CMT) arises in the intravascular photoacoustic imaging (IVPA), in the intravascular ultrasound imaging (IVUS), as well as in radar and sonar. The reduction of the IPVA to the CMT is…

Analysis of PDEs · Mathematics 2013-08-29 Gaik Ambartsoumian , Leonid Kunyansky

Resonant frequency modulation spectroscopy has been previously used as a highly-sensitive method for measuring the output of cold atom interferometers. Using a detailed model that accounts for optical saturation, laser intensities and…

Atomic Physics · Physics 2024-12-11 Ryan J. Thomas , Samuel R. Legge , Simon A. Haine , John D. Close

Photoacoustic tomography (PAT) offers optical contrast, whereas magnetic resonance imaging (MRI) excels in imaging soft tissue and organ anatomy. The fusion of PAT with MRI holds promising application prospects due to their complementary…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Yutian Zhong , Jinchuan He , Zhichao Liang , Shuangyang Zhang , Qianjin Feng , Lijun Lu , Li Qi

Low-count positron emission tomography (PET) reconstruction is a challenging inverse problem due to severe degradations arising from Poisson noise, photon scarcity, and attenuation correction errors. Existing deep learning methods typically…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Zheng Zhang , Hao Tang , Yingying Hu , Zhanli Hu , Jing Qin

Diffusion models have recently emerged as powerful generative priors for solving inverse problems. However, training diffusion models in the pixel space are both data-intensive and computationally demanding, which restricts their…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Bowen Song , Soo Min Kwon , Zecheng Zhang , Xinyu Hu , Qing Qu , Liyue Shen