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Motivated by applications in quantitative photoacoustic imaging, we study inverse problems to a semilinear radiative transport equation (RTE) where we intend to reconstruct absorption coefficients in the equation from single and multiple…

Analysis of PDEs · Mathematics 2020-07-21 Kui Ren , Yimin Zhong

Fluorescence Molecular Tomography (FMT) is a promising technique for non-invasive 3D visualization of fluorescent probes, but its reconstruction remains challenging due to the inherent ill-posedness and reliance on inaccurate or…

Image and Video Processing · Electrical Eng. & Systems 2025-11-07 Shihan Zhao , Jianru Zhang , Yanan Wu , Linlin Li , Siyuan Shen , Xingjun Zhu , Guoyan Zheng , Jiahua Jiang , Wuwei Ren

Image restoration aims to recover high-quality images from degraded observations. When the degradation process is known, the recovery problem can be formulated as an inverse problem, and in a Bayesian context, the goal is to sample a clean…

Image and Video Processing · Electrical Eng. & Systems 2025-10-13 Darshan Thaker , Abhishek Goyal , René Vidal

Photo-acoustic Tomography (PAT) and Thermo-acoustic Tomography (TAT) are medical imaging modalities that combine the high contrast of radiative properties of tissues with the high resolution of ultrasound. In both modalities, a first step…

Medical Physics · Physics 2012-02-15 Guillaume Bal

This paper concerns the quantitative step of the medical imaging modality Thermo-acoustic Tomography (TAT). We model the radiation propagation by a system of Maxwell's equations. We show that the index of refraction of light and the…

Analysis of PDEs · Mathematics 2015-06-17 Guillaume Bal , Ting Zhou

This is the manuscript of the chapter for a planned Handbook of Mathematical Methods in Imaging that surveys the mathematical models, problems, and algorithms of the Thermoacoustic (TAT) and Photoacoustic (PAT) Tomography. TAT and PAT…

Analysis of PDEs · Mathematics 2011-10-04 Peter Kuchment , Leonid Kunyansky

We discuss a quantum mechanical indirect measurement method to recover a position dependent Hamilton matrix from time evolution of coherent quantum mechanical states through an object. A mathematical formulation of this inverse problem…

Mathematical Physics · Physics 2016-06-21 Joonas Ilmavirta

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. If the object…

Medical Physics · Physics 2017-09-08 Joemini Poudel , Thomas P. Matthews , Lei Li , Mark A. Anastasio , Lihong V. Wang

We treat the stability issue for the three dimensional inverse imaging modality called Quantitative Photoacoustic Tomography. We provide universal choices of the illuminations which enable to recover, in a H\"older stable fashion, the…

Analysis of PDEs · Mathematics 2015-05-15 Giovanni Alessandrini , Michele Di Cristo , Elisa Francini , Sergio Vessella

Photoacoustic tomography (PAT) is a newly emerged imaging modality which enables both high optical contrast and acoustic depth of penetration. Reconstructing images of photoacoustic tomography from limited amount of senser data is among one…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Shangqing Tong , Hengrong Lan , Liming Nie , Jianwen Luo , Fei Gao

Photoacoustic computed tomography (PACT) is a rapidly emerging bioimaging modality that seeks to reconstruct an estimate of the absorbed optical energy density within an object. Conventional PACT image reconstruction methods assume a…

Medical Physics · Physics 2016-11-18 Chao Huang , Kun Wang , Robert W. Schoonover , Lihong V. Wang , Mark A. Anastasio

Poisson distributed measurements in inverse problems often stem from Poisson point processes that are observed through discretized or finite-resolution detectors, one of the most prominent examples being positron emission tomography (PET).…

Statistics Theory · Mathematics 2024-07-25 Marco Mauritz , Benedikt Wirth

In this paper we study the problem of photoacoustic inversion in a weakly attenuating medium. We present explicit reconstruction formulas in such media and show that the inversion based on such formulas is moderately ill--posed. Moreover,…

Numerical Analysis · Mathematics 2018-01-17 Otmar Scherzer , Cong Shi

The development of efficient and accurate image reconstruction algorithms is one of the cornerstones of computed tomography. Existing algorithms for quantitative photoacoustic tomography currently operate in a two-stage procedure: First an…

Analysis of PDEs · Mathematics 2015-05-20 Markus Haltmeier , Lukas Neumann , Simon Rabanser

Fluorescence molecular tomography (FMT) is a sensitive optical imaging technology widely used in biomedical research. However, the ill-posedness of the inverse problem poses a huge challenge to FMT reconstruction. Although end-to-end deep…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Peng Zhang , Qianqian Xue , Xingyu Liu , Guanglei Zhang , Wenjian Wang , Jiye Liang

Fluorescent imaging plays a critical role in a myriad of scientific endeavors, particularly in the biological sciences. Three-dimensional imaging of fluorescent intensity often requires serial data acquisition, that is voxel-by-voxel…

Optics · Physics 2015-10-27 Jeffrey J. Field , David G. Winters , Randy A. Bartels

In this article, we revisit iterative methods for solving the inverse problem of photoacoustic tomography in free space. Recently, there have been interesting developments on explicit formulations of the adjoint operator, demonstrating that…

Analysis of PDEs · Mathematics 2017-05-16 Markus Haltmeier , Linh V. Nguyen

Inverse path tracing has recently been applied to joint material and lighting estimation, given geometry and multi-view HDR observations of an indoor scene. However, it has two major limitations: path tracing is expensive to compute, and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Liwen Wu , Rui Zhu , Mustafa B. Yaldiz , Yinhao Zhu , Hong Cai , Janarbek Matai , Fatih Porikli , Tzu-Mao Li , Manmohan Chandraker , Ravi Ramamoorthi

Recently, a novel measurement setup has been introduced to photoacoustic tomography, that collects data in the form of projections of the full 3D acoustic pressure distribution at a certain time instant. Existing imaging algorithms for this…

Numerical Analysis · Mathematics 2018-08-03 Gerhard Zangerl , Markus Haltmeier , Linh V. Nguyen , Robert Nuster

We consider an inverse source problem for partially coherent light propagating in the Fresnel regime. The data is the coherence of the field measured away from the source. The reconstruction is based on a minimum residue formulation, which…

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