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Photoacoustic tomography (PAT) has the potential to recover morphological and functional tissue properties with high spatial resolution. However, previous attempts to solve the optical inverse problem with supervised machine learning were…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Melanie Schellenberg , Janek Gröhl , Kris K. Dreher , Jan-Hinrich Nölke , Niklas Holzwarth , Minu D. Tizabi , Alexander Seitel , Lena Maier-Hein

Photoacoustic tomography is an emerging medical imaging technology whose primary aim is to map the high-contrast optical properties of biological tissues by leveraging high-resolution ultrasound measurements. Mathematically, this can be…

Analysis of PDEs · Mathematics 2025-02-14 Alessandro Felisi

Quantitative image reconstruction in photoacoustic tomography requires the solution of a coupled physics inverse problem involvier light transport and acoustic wave propagation. In this paper we address this issue employing the radiative…

Analysis of PDEs · Mathematics 2017-02-16 Markus Haltmeier , Lukas Neumann , Linh V. Nguyen , Simon Rabanser

Quantitative photoacoustic tomography (QPAT) is a recent hybrid imaging modality that couples optical tomography with ultrasound imaging to achieve high resolution imaging of optical properties of scattering media. Image reconstruction in…

Analysis of PDEs · Mathematics 2015-09-02 Tian Ding , Kui Ren , Sarah Vallelian

We study the inverse source problem in photoacoustic tomography (PAT) for mixed data, which denote a weighted linear combination of the acoustic pressure and its normal derivative on an observation surface. We consider in particular the…

Analysis of PDEs · Mathematics 2022-07-06 Florian Dreier , Markus Haltmeier

Inverse boundary value problems for the radiative transport equation play important roles in optics-based medical imaging techniques such as diffuse optical tomography (DOT) and fluorescence optical tomography (FOT). Despite the rapid…

Numerical Analysis · Mathematics 2015-06-19 Tian Ding , Kui Ren

Quantitative photoacoustic tomography (qPAT) is an imaging technique aimed at estimating chromophore concentrations inside tissues from photoacoustic images, which are formed by combining optical information and ultrasonic propagation. The…

Computational Physics · Physics 2019-12-23 Hwan Goh , Timo Lahivaara , Tanja Tarvainen , Aki Pulkkinen , Owen Dillon , Ruanui Nicholson , Jari Kaipio

The development of efficient and accurate reconstruction methods is an important aspect of tomographic imaging. In this article, we address this issue for photoacoustic tomography. To this aim, we use models for acoustic wave propagation…

Numerical Analysis · Mathematics 2017-11-22 Markus Haltmeier , Richard Kowar , Linh V. Nguyen

Photoacoustic Tomography (PAT) is an emerging biomedical "imaging from coupled physics" technique, in which the image contrast is due to optical absorption, but the information is carried to the surface of the tissue as ultrasound pulses.…

Numerical Analysis · Mathematics 2016-11-03 Simon R. Arridge , Marta M. Betcke , Ben T. Cox , Felix Lucka , Brad E. Treeby

In this paper, we propose a hybrid method to reconstruct the absorption coefficient by fluorescence photoacoustic tomography (FPAT), which combines a squeeze iterative method (SIM) and a nonlinear optimization method. The SIM is to use two…

Numerical Analysis · Mathematics 2019-01-30 Chao Wang , Tie Zhou

In this paper, we describe the numerical reconstruction method for quantitative photoacoustic tomography (QPAT) based on the radiative transfer equation (RTE), which models light propagation more accurately than diffusion approximation…

Quantitative Methods · Quantitative Biology 2017-10-25 Chao Wang , Tie Zhou

Photoacoustic tomography (PAT) is a novel and rapidly promising technique in the field of medical imaging, based on the generation of acoustic waves inside an object of interest by stimulating non-ionizing laser pulses. This acoustic wave…

Analysis of PDEs · Mathematics 2022-02-08 Hyungyeong Jung , Sunghwan Moon

This paper surveys inverse problems arising in several coupled-physics imaging modalities for both medical and geophysical purposes. These include Photo-acoustic Tomography (PAT), Thermo-acoustic Tomography (TAT), Electro-Seismic…

Analysis of PDEs · Mathematics 2016-08-12 Ilker Kocyigit , Ru-Yu Lai , Lingyun Qiu , Yang Yang , Ting Zhou

The development of accurate and efficient image reconstruction algorithms is a central aspect of quantitative photoacoustic tomography (QPAT). In this paper, we address this issues for multi-source QPAT using the radiative transfer equation…

Numerical Analysis · Mathematics 2018-03-29 Simon Rabanser , Lukas Neumann , Markus Haltmeier

Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

Photoacoustic tomography (PAT) is an emerging imaging modality that aims at measuring the high-contrast optical properties of tissues by means of high-resolution ultrasonic measurements. The interaction between these two types of waves is…

Analysis of PDEs · Mathematics 2021-07-27 Giovanni S. Alberti , Paolo Campodonico , Matteo Santacesaria

Photoacoustic tomography (PAT) and thermoacoustic tomography (TAT) both leverage acoustic signals generated by electromagnetic absorption to noninvasively image deep tissues. PAT operates by detecting optical absorption, whereas TAT targets…

Optics · Physics 2026-03-09 Skyler P. Selvin , XuanHao Wang , Handi Deng , Bohua Chen , Cheng Ma

In a medium where the dielectric permittivity is perturbed in the presence of an acoustic wave, optical scattering generates frequency-shifted light. In this paper we consider the inverse problem of recovering the optical properties of this…

Analysis of PDEs · Mathematics 2019-10-14 Francis J. Chung , Jeremy G. Hoskins , John C. Schotland

The attenuation of ultrasound waves in photoacoustic and thermoacoustic imaging presents an important drawback in the applicability of these modalities. This issue has been addressed previously in the applied and theoretical literature, and…

Analysis of PDEs · Mathematics 2021-09-15 Benjamin Palacios

We propose a model-based image reconstruction method for photoacoustic tomography(PAT) involving a novel form of regularization and demonstrate its ability to recover good quality images from significantly reduced size datasets. The…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Nadaparambil Aravindakshan Rejesh , Sandeep Kumar Kalva , Manojit Pramanik , Muthuvel Arigovindan