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Biofilms are complex structures which are inhabited by numerous amount of different species of microorganisms. Due to their ubiquity, they influence human life on an everyday basis. It is therefore important to understand the interactions…

Computational Engineering, Finance, and Science · Computer Science 2025-09-03 Felix Klempt , Hendrik Geisler , Meisam Soleimani , Philipp Junker

A theory of aging based on the principles of the kinetics of chemical reactions and the rules of natural selection of organisms is proposed. The theory is based on a hypothesis that the biochemical processes in the organism can be described…

Populations and Evolution · Quantitative Biology 2024-01-09 Alexey Kondyurin

It is not currently possible to create a living organism ab initio due to the overwhelming complexity of biological systems. In fact, the origin of life mechanism, this being how biological organisms form from non-living matter, is unknown.…

Earth and Planetary Astrophysics · Physics 2021-04-09 Darius Modirrousta-Galian , Giovanni Maddalena

Cell plasma membranes display a dramatically rich structural complexity characterized by functional sub-wavelength domains with specific lipid and protein composition. Under favorable experimental conditions, patterned morphologies can also…

Soft Condensed Matter · Physics 2018-10-02 Nicolas Destainville , Manoel Manghi , Julie Cornet

Free boundaries of biofilms advancing on surfaces evolve according to conservation laws coupled with systems of partial differential equations for velocities, pressures and chemicals affecting cell behavior. Thin film approximations lead to…

Analysis of PDEs · Mathematics 2024-03-18 Ana Carpio , Gema Duro

We study non-equilibrium bacterial colony growth using a geometry-first, time-resolved analysis of morphology. From time-lapse microscopy data, we track the coupled evolution of area, perimeter, and boundary-sensitive shape descriptors…

Soft Condensed Matter · Physics 2026-02-06 Benjamin Evert Himberg , Sanghita Sengupta

Biofilms are microbial collectives that occupy a diverse array of surfaces. The function and evolution of biofilms are strongly influenced by the spatial arrangement of different strains and species within them, but how spatiotemporal…

Populations and Evolution · Quantitative Biology 2018-07-04 Ricardo Martinez-Garcia , Carey D. Nadell , Raimo Hartmann , Knut Drescher , Juan A. Bonachela

Living cells exhibit a complex organization comprising numerous compartments, among which are RNA- and protein-rich membraneless, liquid-like organelles known as biomolecular condensates. Energy-consuming processes regulate their formation…

The general description of formation the cellular structure in the system of interacting particles is proposed. Interactions between particles are presumably well-understood and the phase transition in which can be studied in the scale of…

Statistical Mechanics · Physics 2008-02-22 Bohdan Lev

Microbial ecosystems are commonly modeled by fixed interactions between species in steady exponential growth states. However, microbes often modify their environments so strongly that they are forced out of the exponential state into…

Populations and Evolution · Quantitative Biology 2024-01-08 Avaneesh V. Narla , Terence Hwa , Arvind Murugan

Near a solid boundary, E. coli swims in clockwise circular motion. We provide a hydrodynamic model for this behavior. We show that circular trajectories are natural consequences of force-free and torque-free swimming, and the hydrodynamic…

Soft Condensed Matter · Physics 2016-08-31 Eric Lauga , Willow R. DiLuzio , George M. Whitesides , Howard A. Stone

We present a modelling framework for the dynamics of cells structured by the concentration of a micromolecule they contain. We derive general equations for the evolution of the cell population and of the extra-cellular concentration of the…

Cell Behavior · Quantitative Biology 2024-10-30 Michael Grinfeld , Nigel Mottram , Jozsef Farkas

Life is a complex biological phenomenon represented by numerous chemical, physical and biological processes performed by a biothermodynamic system/cell/organism. Both living organisms and inanimate objects are subject to aging, a biological…

Other Quantitative Biology · Quantitative Biology 2018-01-25 Marko Popovic

Dozens of habitable zone, approximately earth-sized exoplanets are known today. An emerging frontier of exoplanet studies is identifying which of these habitable zone, small planets are actually habitable (have all necessary conditions for…

Bacteria populations rely on mechanisms such as quorum sensing to coordinate complex tasks that cannot be achieved by a single bacterium. Quorum sensing is used to measure the local bacteria population density, and it controls cooperation…

Cell Behavior · Quantitative Biology 2018-02-14 Adam Noel , Yuting Fang , Nan Yang , Dimitrios Makrakis , Andrew W. Eckford

In this perspective article, we discuss bacterial populations as a model system of active matter. It allows for the exploration and characterization of various phases of active matter and brings rich implications for both physics and…

Soft Condensed Matter · Physics 2026-04-16 Kazumasa A. Takeuchi , Daiki Nishiguchi

A new kinetic model for the dynamics of myxobacteria colonies on flat surfaces is derived formally, and first analytical and numerical results are presented. The model is based on the assumption of hard binary collisions of two different…

Analysis of PDEs · Mathematics 2020-08-10 Sabine Hittmeir , Laura Kanzler , Angelika Manhart , Christian Schmeiser

Active nematics are the nonequilibrium analog of passive liquid crystals in which anisotropic units consume free energy to drive emergent behavior. Similar to liquid crystal (LC) molecules in displays, ordering and dynamics in active…

Quantitative Methods · Quantitative Biology 2022-10-10 Japinder Nijjer , Mrityunjay Kothari , Changhao Li , Thomas Henzel , Qiuting Zhang , Jung-Shen B. Tai , Shuang Zhou , Sulin Zhang , Tal Cohen , Jing Yan

Self-propelled bacteria are marvels of nature with a potential to power dynamic materials and microsystems of the future. The challenge is in commanding their chaotic behavior. By dispersing swimming Bacillus subtilis in a…

Soft Condensed Matter · Physics 2016-12-21 Chenhui Peng , Taras Turiv , Yubing Guo , Qi-Huo Wei , Oleg D. Lavrentovich

Dynamics maintaining diversity of cell types in a multi-cellular system are studied in relationship with the plasticity of cellular states. By adopting a simple theoretical framework for intra-cellular chemical reaction dynamics with…

Cell Behavior · Quantitative Biology 2007-05-23 Hiroaki Takagi , Kunihiko Kaneko
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