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A new approach to adaptive design of clinical trials is proposed in a general multiparameter exponential family setting, based on generalized likelihood ratio statistics and optimal sequential testing theory. These designs are easy to…

Statistics Theory · Mathematics 2011-05-25 Jay Bartroff , Tze Leung Lai

Analysis of a probabilistic system often requires to learn the joint probability distribution of its random variables. The computation of the exact distribution is usually an exhaustive precise analysis on all executions of the system. To…

Information Theory · Computer Science 2023-07-19 Fabrizio Biondi , Yusuke Kawamoto , Axel Legay , Louis-Marie Traonouez

We consider an expected-value ranking and selection (R&S) problem where all k solutions' simulation outputs depend on a common parameter whose uncertainty can be modeled by a distribution. We define the most probable best (MPB) to be the…

Methodology · Statistics 2024-04-23 Taeho Kim , Kyoung-kuk Kim , Eunhye Song

The identification of new rare signals in data, the detection of a sudden change in a trend, and the selection of competing models, are among the most challenging problems in statistical practice. These challenges can be tackled using a…

Methodology · Statistics 2022-04-06 Sara Algeri , David A. van Dyk

Uncertainty arises naturally inmany application domains due to, e.g., data entry errors and ambiguity in data cleaning. Prior work in incomplete and probabilistic databases has investigated the semantics and efficient evaluation of ranking…

Databases · Computer Science 2023-05-04 Su Feng , Boris Glavic , Oliver Kennedy

Stochastic differential equations provide a powerful tool for modelling dynamic phenomena affected by random noise. In case of repeated observations of time series for several experimental units, it is often the case that some of the…

Methodology · Statistics 2024-09-06 Fernando Baltazar-Larios , Mogens Bladt , Michael Sørensen

How to find unknown distributions is questioned in many pieces of research. There are several ways to figure them out, but the main question is which acts more reasonably than others. In this paper, we focus on the maximum entropy principle…

Other Statistics · Statistics 2023-07-26 Seyedeh Azadeh Fallah Mortezanejad

The standard efficient testing procedures in the Generalized Inverse Gaussian (GIG) family (also known as Halphen Type A family) are likelihood ratio tests, hence rely on Maximum Likelihood (ML) estimation of the three parameters of the…

Methodology · Statistics 2014-04-23 Angelo Efoevi Koudou , Christophe Ley

Probabilistic programs are typically normal-looking programs describing posterior probability distributions. They intrinsically code up randomized algorithms and have long been at the heart of modern machine learning and approximate…

Programming Languages · Computer Science 2023-02-14 Lutz Klinkenberg , Tobias Winkler , Mingshuai Chen , Joost-Pieter Katoen

Heckman selection model is perhaps the most popular econometric model in the analysis of data with sample selection. The analyses of this model are based on the normality assumption for the error terms, however, in some applications, the…

Methodology · Statistics 2020-06-16 Victor H. Lachos Davila , Marcos O. Prates , Dipak K. Dey

Many models of interest in the natural and social sciences have no closed-form likelihood function, which means that they cannot be treated using the usual techniques of statistical inference. In the case where such models can be…

Computation · Statistics 2012-07-19 Simon Barthelmé , Nicolas Chopin

Bayesian experimental design involves the optimal allocation of resources in an experiment, with the aim of optimising cost and performance. For implicit models, where the likelihood is intractable but sampling from the model is possible,…

Machine Learning · Statistics 2019-02-26 Steven Kleinegesse , Michael Gutmann

We consider the problem of approximating two, possibly unrelated probability distributions from a single complex-valued function $\psi$ and its Fourier transform. We show that this problem always has a solution within a specified degree of…

Mathematical Physics · Physics 2011-01-12 W. D. Flanders , G. Japaridze

We develop a maximum relative entropy formalism to generate optimal approximations to probability distributions. The central results consist in (a) justifying the use of relative entropy as the uniquely natural criterion to select a…

Statistical Mechanics · Physics 2008-10-17 Chih-Yuan Tseng , Ariel Caticha

Generalized variational inference (GVI) provides an optimization-theoretic framework for statistical estimation that encapsulates many traditional estimation procedures. The typical GVI problem is to compute a distribution of parameters…

Optimization and Control · Mathematics 2023-10-27 Aurya S. Javeed , Drew P. Kouri , Thomas M. Surowiec

Over the past decades, there has been a surge of interest in studying low-dimensional structures within high-dimensional data. Statistical factor models $-$ i.e., low-rank plus diagonal covariance structures $-$ offer a powerful framework…

Machine Learning · Statistics 2025-05-20 Daniel Cederberg

The Expectation-Maximization (EM) algorithm is a widely used method for maximum likelihood estimation in models with latent variables. For estimating mixtures of Gaussians, its iteration can be viewed as a soft version of the k-means…

Machine Learning · Statistics 2017-06-06 Constantinos Daskalakis , Christos Tzamos , Manolis Zampetakis

In a distinguishing problem, the input is a sample drawn from one of two distributions and the algorithm is tasked with identifying the source distribution. The performance of a distinguishing algorithm is measured by its advantage, i.e.,…

Computational Complexity · Computer Science 2025-07-22 Ansh Nagda , Prasad Raghavendra

We extend the constrained maximum likelihood estimation theory for parameters of a completely identified model, proposed by Aitchison and Silvey (1958), to parameters arising from a partially identified model. With a partially identified…

Statistics Theory · Mathematics 2016-08-01 Hao Luo , Alexandre Bouchard-Côté , Gabriela Cohen Freue , Paul Gustafson

The Poisson model is frequently employed to describe count data, but in a Bayesian context it leads to an analytically intractable posterior probability distribution. In this work, we analyze a variational Gaussian approximation to the…

Numerical Analysis · Mathematics 2018-02-14 Simon Arridge , Kazufumi Ito , Bangti Jin , Chen Zhang
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