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The evolution of epidemiological parameters, such as instantaneous reproduction number Rt, is important for understanding the transmission dynamics of infectious diseases. Current estimates of time-varying epidemiological parameters often…

Applications · Statistics 2021-10-26 Xian Yang , Shuo Wang , Yuting Xing , Ling Li , Richard Yi Da Xu , Karl J. Friston , Yike Guo

Contact tracing data collected from disease outbreaks has received relatively little attention in the epidemic modelling literature because it is thought to be unreliable: infection sources might be wrongly attributed, or data might be…

Methodology · Statistics 2012-03-16 Chris Jewell , Gareth Roberts

Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…

Applications · Statistics 2026-04-23 Dylan J. Morris , Lauren Kennedy , Andrew J. Black

We introduce a Bayesian sequential data assimilation method for COVID-19 forecasting. It is assumed that suitable transmission, epidemic and observation models are available and previously validated and the transmission and epidemic models…

Insect-borne diseases are diseases carried by insects affecting humans, animals or plants. They have the potential to generate massive outbreaks such as the Zika epidemic in 2015-2016 mostly distributed in the Americas, the Pacific and…

Analysis of PDEs · Mathematics 2020-02-19 Olivier Martin , Yasmil Fernandez-Diclo , Jerome Coville , Samuel Soubeyrand

For many infectious disease outbreaks, the at-risk population changes their behavior in response to the outbreak severity, causing the transmission dynamics to change in real-time. Behavioral change is often ignored in epidemic modeling…

Methodology · Statistics 2023-10-25 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

Early, reliable detection of disease outbreaks is a critical problem today. This paper reports an investigation of the use of causal Bayesian networks to model spatio-temporal patterns of a non-contagious disease (respiratory anthrax…

Applications · Statistics 2012-07-19 Gregory F. Cooper , Denver Dash , John Levander , Weng-Keen Wong , William Hogan , Michael Wagner

Dynamics of the infectious disease transmission is often best understood taking into account the structure of population with respect to specific features, in example age or immunity level. Practical utility of such models depends on the…

Applications · Statistics 2016-06-21 Piotr Gwiazda , Błażej Miasojedow , Magdalena Rosińska

The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…

Methodology · Statistics 2025-03-04 Matthew Adeoye , Xavier Didelot , Simon EF Spencer

Many vector-borne disease epidemic models neglect the fact that in modern human civilization, social awareness as well as self-defence system are overwhelming against advanced propagation of the disease. News are becoming more effortlessly…

Populations and Evolution · Quantitative Biology 2020-02-28 Karunia Putra Wijaya , Joseph Páez Chávez , Dipo Aldila

The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…

Applications · Statistics 2026-03-10 Anastasios Apsemidis , Nikolaos Demiris

Extrinsic environmental factors influence the distribution and population dynamics of many organisms, including insects that are of concern for human health and agriculture. This is particularly true for vector-borne infectious diseases,…

Quantitative Methods · Quantitative Biology 2015-03-31 Leah R. Johnson , Tal Ben-Horin , Kevin D. Lafferty , Amy McNally , Erin Mordecai , Krijn P. Paaijmans , Samraat Pawar , Sadie J. Ryan

We propose an epidemic model for the spread of vector-borne diseases. The model, which is built extending the classical susceptible-infected-susceptible model, accounts for two populations -- humans and vectors -- and for cross-contagion…

Systems and Control · Electrical Eng. & Systems 2025-10-21 Lorenzo Zino , Alessandro Casu , Alessandro Rizzo

Mathematical epidemiological models have a broad use, including both qualitative and quantitative applications. With the increasing availability of data, large-scale quantitative disease spread models can nowadays be formulated. Such models…

Methodology · Statistics 2021-08-10 Stefan Engblom , Robin Eriksson , Stefan Widgren

Reconstructing transmission networks is essential for identifying key factors like superspreaders and high-risk locations, which are critical for developing effective pandemic prevention strategies. In this study, we developed a Bayesian…

Quantitative Methods · Quantitative Biology 2024-09-10 Jianing Xu , Huimin Hu , Gregory Ellison , Lili Yu , Christopher Whalen , Liang Liu

The emergence or adaptation of pathogens may lead to epidemics, highlighting the need for a thorough understanding of pathogen evolution. The tradeoff hypothesis suggests that virulence evolves to reach an optimal transmission intensity…

Populations and Evolution · Quantitative Biology 2024-12-09 Daniel A. M. Villela

Since the last century, deterministic compartmental models have emerged as powerful tools to predict and control epidemic outbreaks, in many cases helping to mitigate their impacts. A key quantity for these models is the so-called Basic…

Populations and Evolution · Quantitative Biology 2022-11-03 Àlex Giménez-Romero , Rosa Flaquer-Galmés , Manuel A. Matias

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

The COVID-19 pandemic provides new motivation for a classic problem in epidemiology: estimating the empirical rate of transmission during an outbreak (formally, the time-varying reproduction number) from case counts. While standard methods…

Methodology · Statistics 2020-12-08 Bryan Wilder , Michael J. Mina , Milind Tambe

When modelling HIV epidemics, it is important to incorporate set-point viral load and its heritability. As set-point viral load distributions can differ significantly amongst epidemics, it is imperative to account for the observed local…

Populations and Evolution · Quantitative Biology 2018-11-28 Pieter Libin , Laurens Hernalsteen , Kristof Theys , Perpetua Gomes , Ana Abecasis , Ann Nowe
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