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A fundamental problem in neuroscience is to characterize the dynamics of spiking from the neurons in a circuit that is involved in learning about a stimulus or a contingency. A key limitation of current methods to analyze neural spiking…

Methodology · Statistics 2017-09-29 Yingzhuo Zhang , Noa Malem-Shinitski , Stephen A Allsop , Kay Tye , Demba Ba

Microarray time course (MTC) gene expression data are commonly collected to study the dynamic nature of biological processes. One important problem is to identify genes that show different expression profiles over time and pathways that are…

Applications · Statistics 2008-12-18 Zhi Wei , Hongzhe Li

Many tasks in human environments require performing a sequence of navigation and manipulation steps involving objects. In unstructured human environments, the location and configuration of the objects involved often change in unpredictable…

Robotics · Computer Science 2015-04-14 Jaeyong Sung , Bart Selman , Ashutosh Saxena

Spatiotemporal gene expression data of the human brain offer insights on the spa- tial and temporal patterns of gene regulation during brain development. Most existing methods for analyzing these data consider spatial and temporal profiles…

Methodology · Statistics 2017-02-27 Tianqi Liu , Ming Yuan , Hongyu Zhao

Statistical Relational Learning (SRL) models have attracted significant attention due to their ability to model complex data while handling uncertainty. However, most of these models have been limited to discrete domains due to their…

Machine Learning · Computer Science 2021-10-20 Yuqiao Chen , Sriraam Natarajan , Nicholas Ruozzi

The developmental process of embryos follows a monotonic order. An embryo can progressively cleave from one cell to multiple cells and finally transform to morula and blastocyst. For time-lapse videos of embryos, most existing developmental…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Stanislav Lukyanenko , Won-Dong Jang , Donglai Wei , Robbert Struyven , Yoon Kim , Brian Leahy , Helen Yang , Alexander Rush , Dalit Ben-Yosef , Daniel Needleman , Hanspeter Pfister

Progressive diseases worsen over time and are characterised by monotonic change in features that track disease progression. Here we connect ideas from two formerly separate methodologies -- event-based and hidden Markov modelling -- to…

Machine Learning · Computer Science 2021-06-07 Peter A. Wijeratne , Daniel C. Alexander

As a relatively new field, network neuroscience has tended to focus on aggregate behaviours of the brain averaged over many successive experiments or over long recordings in order to construct robust brain models. These models are limited…

Neurons and Cognition · Quantitative Biology 2022-05-19 James Wilsenach , Katie Warnaby , Charlotte M. Deane , Gesine Reinert

Stereo matching is a core task for many computer vision and robotics applications. Despite their dominance in traditional stereo methods, the hand-crafted Markov Random Field (MRF) models lack sufficient modeling accuracy compared to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Tongfan Guan , Chen Wang , Yun-Hui Liu

We describe a fully-automatic 3D-segmentation technique for brain MR images. Using Markov random fields the segmentation algorithm captures three important MR features, i.e. non-parametric distributions of tissue intensities, neighborhood…

Computer Vision and Pattern Recognition · Computer Science 2009-03-20 Karsten Held , Elena Rota Kops , Bernd J. Krause , William M. Wells , Ron Kikinis , Hans-Wilhelm Mueller-Gaertner

Markov Random Fields (MRFs), a formulation widely used in generative image modeling, have long been plagued by the lack of expressive power. This issue is primarily due to the fact that conventional MRFs formulations tend to use simplistic…

Computer Vision and Pattern Recognition · Computer Science 2016-09-08 Zhirong Wu , Dahua Lin , Xiaoou Tang

Learning and understanding the typical patterns in the daily activities and routines of people from low-level sensory data is an important problem in many application domains such as building smart environments, or providing intelligent…

Machine Learning · Computer Science 2014-08-14 Truyen Tran , Hung Bui , Svetha Venkatesh

Evolutionary search is well suited for large-scale biophysical brain modeling, where many parameters with nonlinear interactions and no tractable gradients need to be optimized. Standard evolutionary approaches achieve an excellent fit to…

Neural and Evolutionary Computing · Computer Science 2026-04-06 Hormoz Shahrzad , Niharika Gajawelli , Kaitlin Maile , Manish Saggar , Risto Miikkulainen

Motivation: Gene expression during brain development or abnormal development is a biological process that is highly dynamic in spatio and temporal. Due to the lack of comprehensive integration of spatial and temporal dimensions of brain…

Quantitative Methods · Quantitative Biology 2023-10-19 Shanjun Mao , Xiao Huang , Runjiu Chen , Chenyang Zhang , Yizhu Diao , Zongjin Li , Qingzhe Wang , Shan Tang , Shuixia Guo

Mental and cognitive representations are believed to reside on low-dimensional, non-linear manifolds embedded within high-dimensional brain activity. Uncovering these manifolds is key to understanding individual differences in brain…

Machine Learning · Computer Science 2025-05-02 Eloy Geenjaar , Vince Calhoun

Statistical machine learning has widespread application in various domains. These methods include probabilistic algorithms, such as Markov Chain Monte-Carlo (MCMC), which rely on generating random numbers from probability distributions.…

Hardware Architecture · Computer Science 2021-08-03 Ramin Bashizade , Xiangyu Zhang , Sayan Mukherjee , Alvin R. Lebeck

Inspired by the hierarchical hidden Markov models (HHMM), we present the hierarchical semi-Markov conditional random field (HSCRF), a generalisation of embedded undirectedMarkov chains tomodel complex hierarchical, nestedMarkov processes.…

Machine Learning · Statistics 2010-09-13 Tran The Truyen , Dinh Q. Phung , Hung H. Bui , Svetha Venkatesh

Traditional voxel-level multiple testing procedures in neuroimaging, mostly $p$-value based, often ignore the spatial correlations among neighboring voxels and thus suffer from substantial loss of power. We extend the…

Applications · Statistics 2016-07-29 Hai Shu , Bin Nan , Robert Koeppe

We numerically investigate a mean-field Bayesian approach with the assistance of the Markov chain Monte Carlo method to estimate motion velocity fields and probabilistic models simultaneously in consecutive digital images described by…

Computer Vision and Pattern Recognition · Computer Science 2010-04-22 Yuya Inagaki , Jun-ichi Inoue

Using supervised machine learning approaches to recognize human activities from on-body wearable accelerometers generally requires a large amount of labelled data. When ground truth information is not available, too expensive, time…

Machine Learning · Statistics 2013-12-30 Dorra Trabelsi , Samer Mohammed , Faicel Chamroukhi , Latifa Oukhellou , Yacine Amirat
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