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High-dimensional multi-source data are encountered in many fields. Despite recent developments on the integrative dimension reduction of such data, most existing methods cannot easily accommodate data of multiple types (e.g., binary or…

Methodology · Statistics 2018-08-08 Huichen Zhu , Gen Li , Eric F. Lock

Multiple imputation is a well-established general technique for analyzing data with missing values. A convenient way to implement multiple imputation is sequential regression multiple imputation (SRMI), also called chained equations…

Background: Existing guidelines for handling missing data are generally not consistent with the goals of prediction modelling, where missing data can occur at any stage of the model pipeline. Multiple imputation (MI), often heralded as the…

Methodology · Statistics 2022-06-27 Rose Sisk , Matthew Sperrin , Niels Peek , Maarten van Smeden , Glen P. Martin

Background: Biological data often originate from samples containing mixtures of subpopulations, corresponding e.g. to distinct cellular phenotypes. However, identification of distinct subpopulations may be difficult if biological…

Graphics · Computer Science 2014-07-09 Justin Feigelman , Fabian J. Theis , Carsten Marr

We propose a copula based method to handle missing values in multivariate data of mixed types in multilevel data sets. Building upon the extended rank likelihood of \cite{hoff2007extending} and the multinomial probit model, our model is a…

Methodology · Statistics 2017-02-28 Jiali Wang , Bronwyn Loong , Anton H. Westveld , Alan H. Welsh

Item nonresponse is frequently encountered in practice. Ignoring missing data can lose efficiency and lead to misleading inference. Fractional imputation is a frequentist approach of imputation for handling missing data. However, the…

Methodology · Statistics 2018-09-18 Hejian Sang , Jae Kwang Kim

This article introduces the Python package gcimpute for missing data imputation. gcimpute can impute missing data with many different variable types, including continuous, binary, ordinal, count, and truncated values, by modeling data as…

Methodology · Statistics 2022-03-11 Yuxuan Zhao , Madeleine Udell

Multiple imputation (MI) has become popular for analyses with missing data in medical research. The standard implementation of MI is based on the assumption of data being missing at random (MAR). However, for missing data generated by…

Methodology · Statistics 2019-01-03 Tra My Pham , James R Carpenter , Tim P Morris , Angela M Wood , Irene Petersen

A common approach for handling missing values in data analysis pipelines is multiple imputation via software packages such as MICE (Van Buuren and Groothuis-Oudshoorn, 2011) and Amelia (Honaker et al., 2011). These packages typically assume…

Methodology · Statistics 2025-07-23 Trung Phung , Kyle Reese , Ilya Shpitser , Rohit Bhattacharya

Missing data is a commonly occurring problem in practice. Many imputation methods have been developed to fill in the missing entries. However, not all of them can scale to high-dimensional data, especially the multiple imputation…

Machine Learning · Computer Science 2023-03-21 Thu Nguyen , Hoang Thien Ly , Michael Alexander Riegler , Pål Halvorsen , Hugo L. Hammer

Missing data are ubiquitous in real world applications and, if not adequately handled, may lead to the loss of information and biased findings in downstream analysis. Particularly, high-dimensional incomplete data with a moderate sample…

Machine Learning · Computer Science 2022-12-23 Zongyu Dai , Zhiqi Bu , Qi Long

Many real-world datasets contain missing entries and mixed data types including categorical and ordered (e.g. continuous and ordinal) variables. Imputing the missing entries is necessary, since many data analysis pipelines require complete…

Methodology · Statistics 2022-10-14 Yuxuan Zhao , Alex Townsend , Madeleine Udell

Missing observations are pervasive throughout empirical research, especially in the social sciences. Despite multiple approaches to dealing adequately with missing data, many scholars still fail to address this vital issue. In this paper,…

Data for which a set of objects is described by multiple distinct feature sets (called views) is known as multi-view data. When missing values occur in multi-view data, all features in a view are likely to be missing simultaneously. This…

Machine Learning · Statistics 2024-06-21 Wouter van Loon , Marjolein Fokkema , Frank de Vos , Marisa Koini , Reinhold Schmidt , Mark de Rooij

In clinical trials, mixed effects models for repeated measures (MMRM) and pattern mixture models (PMM) are often used to analyze longitudinal continuous outcomes. We describe a simple missing data imputation algorithm for the MMRM that can…

Methodology · Statistics 2016-10-13 Yongqiang Tang

Modern data acquisition based on high-throughput technology is often facing the problem of missing data. Algorithms commonly used in the analysis of such large-scale data often depend on a complete set. Missing value imputation offers a…

Applications · Statistics 2014-06-03 Daniel J. Stekhoven , Peter Bühlmann

Multiple imputation is a highly recommended technique to deal with missing data, but the application to longitudinal datasets can be done in multiple ways. When a new wave of longitudinal data arrives, we can treat the combined data of…

Methodology · Statistics 2026-05-18 X. M. Kavelaars , S. van Buuren , J. R. van Ginkel

Multivariate imputation by chained equations (MICE) is one of the most popular approaches to address missing values in a data set. This approach requires specifying a univariate imputation model for every variable under imputation. The…

Methodology · Statistics 2023-11-01 Edoardo Costantini , Kyle M. Lang , Klaas Sijtsma

This paper presents algorithm for missing values imputation in categorical data. The algorithm is based on using association rules and is presented in three variants. Experimental shows better accuracy of missing values imputation using the…

Machine Learning · Computer Science 2012-11-09 Jiří Kaiser

Multiple imputation (MI) is a popular method for handling missing data. Auxiliary variables can be added to the imputation model(s) to improve MI estimates. However, the choice of which auxiliary variables to include in the imputation model…