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Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees. Substitutions in sequences are modelled through a continuous-time Markov process, characterised by an instantaneous rate matrix, which standard…

Populations and Evolution · Quantitative Biology 2020-07-20 Naomi E. Hannaford , Sarah E. Heaps , Tom M. W. Nye , Tom A. Williams , T. Martin Embley

Understanding the evolutionary relationship among species is of fundamental importance to the biological sciences. The location of the root in any phylogenetic tree is critical as it gives an order to evolutionary events. None of the…

Populations and Evolution · Quantitative Biology 2016-11-15 Benjamin D Kaehler

Rooted phylogenetic networks are used to describe evolutionary histories that contain non-treelike evolutionary events such as hybridization and horizontal gene transfer. In some cases, such histories can be described by a phylogenetic…

Populations and Evolution · Quantitative Biology 2016-10-03 Laura Jetten , Leo van Iersel

Phylogenetic networks are a generalization of phylogenetic trees allowing for the representation of non-treelike evolutionary events such as hybridization. Typically, such networks have been analyzed based on their `level', i.e. based on…

Populations and Evolution · Quantitative Biology 2020-05-11 Mareike Fischer , Michelle Galla , Lina Herbst , Yangjing Long , Kristina Wicke

Neutral macroevolutionary models, such as the Yule model, give rise to a probability distribution on the set of discrete rooted binary trees over a given leaf set. Such models can provide a signal as to the approximate location of the root…

Populations and Evolution · Quantitative Biology 2012-03-28 Mike Steel

Estimating phylogenetic trees is an important problem in evolutionary biology, environmental policy and medicine. Although trees are estimated, their uncertainties are discarded by mathematicians working in tree space. Here we explicitly…

Methodology · Statistics 2017-10-16 Amy D. Willis , Rayna C. Bell

Phylogenetic networks are a generalisation of phylogenetic trees that allow for more complex evolutionary histories that include hybridisation-like processes. It is of considerable interest whether a network can be considered `tree-like' or…

Populations and Evolution · Quantitative Biology 2017-11-21 Michael Hendriksen

The inference of the evolutionary history of a collection of organisms is a problem of fundamental importance in evolutionary biology. The abundance of DNA sequence data arising from genome sequencing projects has led to significant…

Populations and Evolution · Quantitative Biology 2015-07-07 Julia Chifman , Laura Kubatko

Terraces are potentially large sets of trees with precisely the same likelihood or parsimony score, which can be induced by missing sequences in partitioned multi-locus phylogenetic data matrices. The set of trees on a terrace can be…

Populations and Evolution · Quantitative Biology 2014-10-30 Michael J Sanderson , Michelle M. McMahon , Alexandros Stamatakis , Derrick J. Zwickl , Mike Steel

Tree-based networks are a class of phylogenetic networks that attempt to formally capture what is meant by "tree-like" evolution. A given non-tree-based phylogenetic network, however, might appear to be very close to being tree-based, or…

Populations and Evolution · Quantitative Biology 2020-01-17 Mareike Fischer , Andrew Francis

Phylogenetic networks are a generalization of phylogenetic trees that are used to represent non-tree-like evolutionary histories that arise in organisms such as plants and bacteria, or uncertainty in evolutionary histories. An…

Populations and Evolution · Quantitative Biology 2017-12-08 Andrew Francis , Katharina Huber , Vincent Moulton

Phylogenetics is now fundamental in life sciences, providing insights into the earliest branches of life and the origins and spread of epidemics. However, finding suitable phylogenies from the vast space of possible trees remains…

Populations and Evolution · Quantitative Biology 2024-01-24 Matthew J Penn , Neil Scheidwasser , Joseph Penn , Christl A Donnelly , David A Duchêne , Samir Bhatt

The evolutionary relationships among organisms have traditionally been represented using rooted phylogenetic trees. However, due to reticulate processes such as hybridization or lateral gene transfer, evolution cannot always be adequately…

Populations and Evolution · Quantitative Biology 2022-01-20 Sungsik Kong , Joan Carles Pons , Laura Kubatko , Kristina Wicke

Predicting the ancestral sequences of a group of homologous sequences related by a phylogenetic tree has been the subject of many studies, and numerous methods have been proposed to this purpose. Theoretical results are available that show…

Populations and Evolution · Quantitative Biology 2013-09-05 Olivier Gascuel , Mike Steel

This paper studies the relationship between undirected (unrooted) and directed (rooted) phylogenetic networks. We describe a polynomial-time algorithm for deciding whether an undirected nonbinary phylogenetic network, given the locations of…

Data Structures and Algorithms · Computer Science 2023-10-02 Katharina T. Huber , Leo van Iersel , Remie Janssen , Mark Jones , Vincent Moulton , Yukihiro Murakami , Charles Semple

Correlations between two variables of a high-dimensional system can be indicative of an underlying interaction, but can also result from indirect effects. Inverse Ising inference is a method to distinguish one from the other. Essentially,…

Populations and Evolution · Quantitative Biology 2014-12-10 Benedikt Obermayer , Erel Levine

Gene trees are evolutionary trees representing the ancestry of genes sampled from multiple populations. Species trees represent populations of individuals -- each with many genes -- splitting into new populations or species. The coalescent…

Populations and Evolution · Quantitative Biology 2010-07-30 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

The statistical estimation of phylogenies is always associated with uncertainty, and accommodating this uncertainty is an important component of modern phylogenetic comparative analysis. The birth-death polytomy resolver is a method of…

Quantitative Methods · Quantitative Biology 2015-03-18 Daniel L. Rabosky

The hierarchical and recursive expressive capability of rooted trees is applicable to represent statistical models in various areas, such as data compression, image processing, and machine learning. On the other hand, such hierarchical…

Machine Learning · Computer Science 2022-01-25 Yuta Nakahara , Shota Saito , Akira Kamatsuka , Toshiyasu Matsushima

Identifiability of evolutionary tree models has been a recent topic of discussion and some models have been shown to be non-identifiable. A coalescent-based rooted population tree model, originally proposed by Nielsen et al. 1998 [2], has…

Populations and Evolution · Quantitative Biology 2013-04-15 Arindam RoyChoudhury
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