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The problem of a solute described by Quantum Chemistry within a solvent represented as a polarizable continuum model (PCM) is here reformulated in terms of the open quantum systems (OQS) theory. Using its stochastic Schr\"{o}dinger Equation…

Chemical Physics · Physics 2020-10-28 Ciro A. Guido , M. Rosa , R. Cammi , S. Corni

We describe a highly optimized implementation of MPI domain decomposition in a GPU-enabled, general-purpose molecular dynamics code, HOOMD-blue (Anderson and Glotzer, arXiv:1308.5587). Our approach is inspired by a traditional CPU-based…

Implicit time integration is key to robustly simulating stiff materials and large deformations, but its performance is often dominated by repeatedly solving large linear systems. Adaptive coarsening can reduce this cost by concentrating…

Graphics · Computer Science 2026-05-07 Xuan Wang , Zhaofeng Luo , Minchen Li , Taku Komura , Kemeng Huang

The High Energy Physics (HEP) experiments, such as those at the Large Hadron Collider (LHC), traditionally consume large amounts of CPU cycles for detector simulations and data analysis, but rarely use compute accelerators such as GPUs. As…

High Energy Physics - Experiment · Physics 2022-03-17 Zhihua Dong , Heather Gray , Charles Leggett , Meifeng Lin , Vincent R. Pascuzzi , Kwangmin Yu

We present LayerPCM, an extension of the polarizable-continuum model coupled to real-time time-dependent density-functional theory for an efficient and accurate description of the electrostatic interactions between molecules and…

Materials Science · Physics 2021-06-17 Jannis Krumland , Gabriel Gil , Stefano Corni , Caterina Cocchi

Accurate prediction of binding free energies is critical to streamlining the drug development and protein design process. With the advent of GPU acceleration, absolute alchemical methods, which simulate the removal of ligand electrostatics…

Biological Physics · Physics 2021-03-17 Edward King , Ruxi Qi , Han Li , Ray Luo , Erick Aitchison

Background: The numerical solution of few-body scattering problems with realistic interactions is a difficult problem that normally must be solved on powerful supercomputers, taking a lot of computer time. This strongly limits the…

Nuclear Theory · Physics 2014-07-09 V. N. Pomerantsev , V. I. Kukulin , O. A. Rubtsova

Principal component analysis (PCA) is a statistical technique commonly used in multivariate data analysis. However, PCA can be difficult to interpret and explain since the principal components (PCs) are linear combinations of the original…

Mathematical Software · Computer Science 2013-12-24 W. Liu , H. Zhang , D. Tao , Y. Wang , K. Lu

The adoption of hybrid GPU-CPU nodes in traditional supercomputing platforms opens acceleration opportunities for electronic structure calculations in materials science and chemistry applications, where medium sized Hermitian generalized…

Numerical Analysis · Computer Science 2012-07-10 Raffaele Solcà , Thomas C. Schulthess , Azzam Haidar , Stanimire Tomov , Ichitaro Yamazaki , Jack Dongarra

The DD-CPM software library provides a set of tools for the discretization and solution of problems arising from the closest point method (CPM) for partial differential equations on surfaces. The solvers are built on top of the well-known…

Numerical Analysis · Mathematics 2022-09-28 Ian C. T. May , Ronald D. Haynes , Steven J. Ruuth

B-spline modeling is fundamental to CAD systems, and its evaluation and manipulation algorithms currently in use were developed decades ago, specifically for CPU architectures. While remaining effective for many applications, these…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-17 Jiayu Wu , Qiang Zou

Methods for electronic structure based on Gaussian and molecular orbital discretizations offer a well established, compact representation that forms much of the foundation of correlated quantum chemistry calculations on both classical and…

We present the extension of the Tinker-HP package (Lagard\`ere et al., Chem. Sci., 2018,9, 956-972) to the use of Graphics Processing Unit (GPU) cards to accelerate molecular dynamics simulations using polarizable many-body force fields.…

We created an efficient algorithm suitable for graphics processing units (GPUs) to perform Monte Carlo simulations of a subset of reaction-diffusion models. The algorithm uses techniques that are specific to GPU programming, and combines…

Computational Physics · Physics 2013-03-06 R. D. Schram

Classical molecular dynamics (MD) simulations are important tools in life and material sciences since they allow studying chemical and biological processes in detail. However, the inherent scalability problem of particle-particle…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-08-14 Michael Schaffner , Luca Benini

Sequential robot manipulation tasks require finding collision-free trajectories that satisfy geometric constraints across multiple object interactions in potentially high-dimensional configuration spaces. Solving these problems in real-time…

Robotics · Computer Science 2025-10-14 Lucas Chen , Shrutheesh Raman Iyer , Zachary Kingston

We introduce a high-level graphical framework for designing and analysing quantum error correcting codes, centred on what we term the coherent parity check (CPC). The graphical formulation is based on the diagrammatic tools of the…

Quantum Physics · Physics 2023-08-21 Nicholas Chancellor , Aleks Kissinger , Joschka Roffe , Stefan Zohren , Dominic Horsman

Probabilistic computing using probabilistic bits (p-bits) presents an efficient alternative to traditional CMOS logic for complex problem-solving, including simulated annealing and machine learning. Realizing p-bits with emerging devices…

Machine Learning · Computer Science 2026-01-22 Naoya Onizawa , Takahiro Hanyu

High-performance graphical processing units (GPU) are used for the repeated parallelised propagation of non-linear partial differential equations on large spatio-temporal grids. The main challenge results as a combination of the requirement…

Graphics Processing Units (GPUs) are having a transformational effect on numerical lattice quantum chromodynamics (LQCD) calculations of importance in nuclear and particle physics. The QUDA library provides a package of mixed precision…

High Energy Physics - Lattice · Physics 2010-12-06 Ronald Babich , Michael A. Clark , Bálint Joó
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