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Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging technique that holds great promise for biomedical imaging. PACT is a hybrid imaging method that can exploit the strong endogenous…

Medical Physics · Physics 2019-05-13 Joemini Poudel , Yang Lou , Mark A. Anastasio

Photoacoustic computed tomography (PACT) is a promising imaging modality that combines the advantages of optical contrast with ultrasound detection. Utilizing ultrasound transducers with larger surface areas can improve detection…

Photoacoustic (PA) computed tomography (PACT) shows great potentials in various preclinical and clinical applications. A great number of measurements are the premise that obtains a high-quality image, which implies a low imaging rate or a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Hengrong Lan , Juze Zhang , Changchun Yang , Fei Gao

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. If the object…

Medical Physics · Physics 2017-09-08 Joemini Poudel , Thomas P. Matthews , Lei Li , Mark A. Anastasio , Lihong V. Wang

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

Dynamic Photoacoustic Computed Tomography (PACT) is an important imaging technique for monitoring physiological processes, capable of providing high-contrast images of optical absorption at much greater depths than traditional optical…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Youshen Xiao , Yiling Shi , Ruixi Sun , Hongjiang Wei , Fei Gao , Yuyao Zhang

Photoacoustic imaging (PAI) is a non-invasive imaging modality that detects the ultrasound signal generated from tissue with light excitation. Photoacoustic computed tomography (PACT) uses unfocused large-area light to illuminate the target…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Hengrong Lan , Jiali Gong , Fei Gao

Photoacoustic computed tomography (PACT) is a non-invasive imaging modality, similar to ultrasound, with wide-ranging medical applications. Conventional PACT images are degraded by wavefront distortion caused by the heterogeneous speed of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Tianao Li , Manxiu Cui , Cheng Ma , Emma Alexander

High-quality imaging in photoacoustic computed tomography (PACT) usually requires a high-channel count system for dense spatial sampling around the object to avoid aliasing-related artefacts. To reduce system complexity, various image…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Bowei Yao , Shilong Cui , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Jingyi Yu , Yuyao Zhang , Xiran Cai

Photoacoustic computed tomography (PACT) is an emerging imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the photoacoustically induced initial pressure distribution within tissue. The…

Photoacoustic computed tomography (PACT) is a rapidly emerging bioimaging modality that seeks to reconstruct an estimate of the absorbed optical energy density within an object. Conventional PACT image reconstruction methods assume a…

Medical Physics · Physics 2016-11-18 Chao Huang , Kun Wang , Robert W. Schoonover , Lihong V. Wang , Mark A. Anastasio

Photoacoustic Computed Tomography (PACT) is a major configuration of photoacoustic imaging, a hybrid noninvasive modality for both functional and molecular imaging. PACT has rapidly gained importance in the field of biomedical imaging due…

Photoacoustic computed tomography (PACT) combines the optical contrast of optical imaging and the penetrability of sonography. In this work, we develop a novel PACT system to provide real-time imaging, which is achieved by a 120-elements…

Image and Video Processing · Electrical Eng. & Systems 2021-05-10 Hengrong Lan , Daohuai Jiang , Feng Gao , Fei Gao

Photoacoustic imaging (PAI) represents an innovative biomedical imaging modality that harnesses the advantages of optical resolution and acoustic penetration depth while ensuring enhanced safety. Despite its promising potential across a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lei Wang , Weiming Zeng , Kai Long , Hongyu Chen , Rongfeng Lan , Li Liu , Wai Ting Siok , Nizhuan Wang

Photoacoustic tomography (PAT) is a rapidly-evolving medical imaging modality that combines optical absorption contrast with ultrasound imaging depth. One challenge in PAT is image reconstruction with inadequate acoustic signals due to…

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging modality that has great potential for a wide range of biomedical imaging applications. In this Note, we derive a hybrid reconstruction…

Analysis of PDEs · Mathematics 2015-06-11 Kun Wang , Mark A. Anastasio

Photoacoustic tomography (PAT) is a medical imaging modality that can provide high-resolution tissue images based on the optical absorption. Classical reconstruction methods for quantifying the absorption coefficients rely on sufficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Anssi Manninen , Janek Gröhl , Felix Lucka , Andreas Hauptmann

Photo-acoustic tomography (PAT) aims to leverage the photo-acoustic coupling between optical absorption of light sources and ultrasound (US) emission to obtain high contrast reconstructions of optical parameters with the high resolution of…

Analysis of PDEs · Mathematics 2016-09-21 Guillaume Bal , Amir Moradifam

Photoacoustic tomography (PAT) is a hybrid imaging modality that intends to construct high-resolution images of optical properties of heterogeneous media from measured acoustic data generated by the photoacoustic effect. To date, most of…

Numerical Analysis · Mathematics 2019-08-07 Christina Frederick , Kui Ren , Sarah Vallélian

Photoacoustic computed tomography (PACT) is emerging as a new technique for functional brain imaging, primarily due to its capabilities in label-free hemodynamic imaging. Despite its potential, the transcranial application of PACT has…

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