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Recent emergence of next-generation DNA sequencing technology has enabled acquisition of genetic information at unprecedented scales. In order to determine the genetic blueprint of an organism, sequencing platforms typically employ…

Genomics · Quantitative Biology 2015-06-19 Xiaohu Shen , Manohar Shamaiah , Haris Vikalo

Data-efficient image classification is a challenging task that aims to solve image classification using small training data. Neural network-based deep learning methods are effective for image classification, but they typically require…

Neural and Evolutionary Computing · Computer Science 2022-12-05 Ying Bi , Bing Xue , Mengjie Zhang

The preservation of soil health is a critical challenge in the 21st century due to its significant impact on agriculture, human health, and biodiversity. We provide the first deep investigation of the predictive potential of machine…

Machine Learning · Statistics 2024-02-20 Rosa Aghdam , Xudong Tang , Shan Shan , Richard Lankau , Claudia Solís-Lemus

Next-generation sequencing technologies have enhanced the scope of Internet-of-Things (IoT) to include genomics for personalized medicine through the increased availability of an abundance of genome data collected from heterogeneous sources…

We present a new approach, called meta-meta classification, to learning in small-data settings. In this approach, one uses a large set of learning problems to design an ensemble of learners, where each learner has high bias and low variance…

Machine Learning · Computer Science 2020-06-16 Arkabandhu Chowdhury , Dipak Chaudhari , Swarat Chaudhuri , Chris Jermaine

Future upgrades to the LHC will pose considerable challenges for traditional particle track reconstruction methods. We investigate how artificial Neural Networks and Deep Learning could be used to complement existing algorithms to increase…

Instrumentation and Detectors · Physics 2019-10-16 Felix Dietrich

Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Broadly categorized in three types (i.e., sequences, images, and signals), these…

Quantitative Methods · Quantitative Biology 2020-03-03 Mufti Mahmud , M Shamim Kaiser , Amir Hussain

Genome and metagenome comparisons based on large amounts of next-generation sequencing (NGS) data pose significant challenges for alignment-based approaches due to the huge data size and the relatively short length of the reads.…

Quantitative Methods · Quantitative Biology 2018-03-28 Jie Ren , Xin Bai , Yang Young Lu , Kujin Tang , Ying Wang , Gesine Reinert , Fengzhu Sun

Gradient based meta-learning methods are prone to overfit on the meta-training set, and this behaviour is more prominent with large and complex networks. Moreover, large networks restrict the application of meta-learning models on low-power…

Machine Learning · Computer Science 2022-06-06 Arnav Chavan , Rishabh Tiwari , Udbhav Bamba , Deepak K. Gupta

Sequence classification has numerous applications in various fields. Despite extensive studies in the last decades, many challenges still exist, particularly in pattern-based methods. Existing pattern-based methods measure the…

Machine Learning · Computer Science 2023-10-23 Junjie Dong , Mudi Jiang , Lianyu Hu , Zengyou He

Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker…

Methodology · Statistics 2025-11-13 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

Representation learning is important for solving sequence-to-sequence problems in natural language processing. Representation learning transforms raw data into vector-form representations while preserving their features. However, data with…

Computation and Language · Computer Science 2023-01-12 Yunhao Yang , Zhaokun Xue , Andrew Whinston

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

Emerging Technologies · Computer Science 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

Sample re-weighting strategies provide a promising mechanism to deal with imperfect training data in machine learning, such as noisily labeled or class-imbalanced data. One such strategy involves formulating a bi-level optimization problem…

Machine Learning · Computer Science 2023-02-10 Yinjun Wu , Adam Stein , Jacob Gardner , Mayur Naik

As with any task, the process of building machine learning models can benefit from prior experience. Meta-learning for classifier selection leverages knowledge about the characteristics of different datasets and/or the past performance of…

Machine Learning · Computer Science 2025-08-26 Sebastian Maldonado , Carla Vairetti , Ignacio Figueroa

Many different machine learning algorithms exist; taking into account each algorithm's hyperparameters, there is a staggeringly large number of possible alternatives overall. We consider the problem of simultaneously selecting a learning…

Machine Learning · Computer Science 2013-03-08 Chris Thornton , Frank Hutter , Holger H. Hoos , Kevin Leyton-Brown

Advances in high-throughput technologies have originated an ever-increasing availability of omics datasets. The integration of multiple heterogeneous data sources is currently an issue for biology and bioinformatics. Multiple kernel…

Machine Learning · Statistics 2024-12-04 Mitja Briscik , Gabriele Tazza , Marie-Agnes Dillies , László Vidács , Sébastien Dejean

As the size and richness of available datasets grow larger, the opportunities for solving increasingly challenging problems with algorithms learning directly from data grow at the same pace. Consequently, the capability of learning…

Machine Learning · Computer Science 2019-12-13 Raffaello Camoriano

Deep Neural Networks (DNNs) face challenges during deployment due to covariate shift, i.e., data distribution shifts between development and deployment contexts. Fine-tuning adapts pre-trained models to new contexts requiring smaller…

Machine Learning · Computer Science 2025-09-19 Amin Abbasishahkoo , Mahboubeh Dadkhah , Lionel Briand , Dayi Lin

MicroRNAs (miRNAs) are endogenous small non-coding RNAs that play an important role in post-transcriptional gene regulation. However, the experimental determination of miRNA sequence and structure is both expensive and time-consuming.…

Genomics · Quantitative Biology 2021-06-30 Shyaman Jayasundara , Sandali Lokuge , Puwasuru Ihalagedara , Damayanthi Herath