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Related papers: Large-scale Machine Learning for Metagenomics Sequ…

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Next Generation Sequencing can sample the whole genome (WGS) or the 1-2% of the genome that codes for proteins called the whole exome (WES). Machine learning approaches to variant calling achieve high accuracy in WGS data, but the reduced…

Genomics · Quantitative Biology 2019-11-19 Ren Yi , Pi-Chuan Chang , Gunjan Baid , Andrew Carroll

Current metagenomic analysis algorithms require significant computing resources, can report excessive false positives (type I errors), may miss organisms (type II errors / false negatives), or scale poorly on large datasets. This paper…

Databases · Computer Science 2015-01-23 Ashley Mae Conard , Stephanie Dodson , Jeremy Kepner , Darrell Ricke

Enabling robots to solve multiple manipulation tasks has a wide range of industrial applications. While learning-based approaches enjoy flexibility and generalizability, scaling these approaches to solve such compositional tasks remains a…

Machine Learning · Computer Science 2021-09-17 Michael H. Lim , Andy Zeng , Brian Ichter , Maryam Bandari , Erwin Coumans , Claire Tomlin , Stefan Schaal , Aleksandra Faust

Deep learning has revolutionized many industries by enabling models to automatically learn complex patterns from raw data, reducing dependence on manual feature engineering. However, deep learning algorithms are sensitive to input data, and…

Machine Learning · Computer Science 2025-07-21 Mert Sehri , Zehui Hua , Francisco de Assis Boldt , Patrick Dumond

Multiple Sequence Alignment (MSA) is one of the most computationally intensive tasks in Computational Biology. Existing best known solutions for multiple sequence alignment take several hours (in some cases days) of computation time to…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-01-20 Fahad Saeed , Ashfaq Khokhar

Recent studies in DNA sequence classification have leveraged sophisticated machine learning techniques, achieving notable accuracy in categorizing complex genomic data. Among these, methods such as k-mer counting have proven effective in…

Genomics · Quantitative Biology 2024-01-26 Şükrü Ozan

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

The recent development of metagenomic sequencing makes it possible to sequence microbial genomes including viruses in an environmental sample. Identifying viral sequences from metagenomic data is critical for downstream virus analyses. The…

Genomics · Quantitative Biology 2018-06-21 Jie Ren , Kai Song , Chao Deng , Nathan A. Ahlgren , Jed A. Fuhrman , Yi Li , Xiaohui Xie , Fengzhu Sun

Advances in high-throughput sequencing technologies and bioinformatics approaches over almost the last three decades have substantially increased our ability to explore microorganisms and their functions-including those that have yet to be…

Metagenomics has led to significant advancements in many fields. Metagenomic analysis commonly involves the key tasks of determining the species present in a sample and their relative abundances. These tasks require searching large…

In this paper, we tackle the problem of selecting the optimal model for a given structured pattern classification dataset. In this context, a model can be understood as a classifier and a hyperparameter configuration. The proposed…

Machine Learning · Computer Science 2022-10-27 Gonzalo Nápoles , Isel Grau , Çiçek Güven , Orçun Özdemir , Yamisleydi Salgueiro

Machine learning techniques are steadily becoming more important in modern biology, and are used to build predictive models, discover patterns, and investigate biological problems. However, models trained on one dataset are often not…

Quantitative Methods · Quantitative Biology 2024-05-30 Seyedmehdi Orouji , Martin C. Liu , Tal Korem , Megan A. K. Peters

Data pruning, or instance selection, is an important problem in machine learning especially in terms of nearest neighbour classifier. However, in data pruning which speeds up the prediction phase, there is an issue related to the speed and…

Machine Learning · Computer Science 2025-01-22 Marcin Blachnik , Piotr Ciepliński

This paper studies the fast adaptive beamforming for the multiuser multiple-input single-output downlink. Existing deep learning-based approaches assume that training and testing channels follow the same distribution which causes task…

Information Theory · Computer Science 2021-09-21 Juping Zhang , Yi Yuan , Gan Zheng , Ioannis Krikidis , Kai-Kit Wong

MetaScope is a fast and accurate tool for analyzing (host-associated) metagenome datasets. Sequence alignment of reads against the host genome (if requested) and against microbial Genbank is performed using a new DNA aligner called SASS.…

Genomics · Quantitative Biology 2015-11-30 Benjamin Buchfink , Daniel H. Huson , Chao Xie

Recent advances in genomic sequencing technology have resulted in an abundance of genome sequence data. Despite the progress in interpreting those data, there remains a broad scope for their translation into clinical and societal benefits.…

Genomics · Quantitative Biology 2021-12-13 Abhinav Jain , Greg Slabaugh , Deepti Gurdasani

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Designing RNA molecules has garnered recent interest in medicine, synthetic biology, biotechnology and bioinformatics since many functional RNA molecules were shown to be involved in regulatory processes for transcription, epigenetics and…

Machine Learning · Computer Science 2019-04-15 Frederic Runge , Danny Stoll , Stefan Falkner , Frank Hutter

Deep sequencing has enabled the investigation of a wide range of environmental microbial ecosystems, but the high memory requirements for {\em de novo} assembly of short-read shotgun sequencing data from these complex populations are an…

Genomics · Quantitative Biology 2015-06-03 Jason Pell , Arend Hintze , Rosangela Canino-Koning , Adina Howe , James M. Tiedje , C. Titus Brown

Multi-model fitting has been extensively studied from the random sampling and clustering perspectives. Most assume that only a single type/class of model is present and their generalizations to fitting multiple types of models/structures…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Xun Xu , Loong-Fah Cheong , Zhuwen Li