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How cells reliably infer information about their environment is a fundamentally important question. While sensing and signaling generally start with cell-surface receptors, the degree of accuracy with which a cell can measure external…

Biological Physics · Physics 2016-01-20 Gerardo Aquino , Ned S. Wingreen , Robert G. Endres

Molecular communication is a novel approach for data transmission between miniaturized devices, especially in contexts where electrical signals are to be avoided. The communication is based on sending molecules (or other particles) at nano…

Emerging Technologies · Computer Science 2023-08-08 Max Bartunik , Jens Kirchner , Oliver Keszocze

Important cellular processes such as migration, differentiation, and development often rely on precise timing. Yet, the molecular machinery that regulates timing is inherently noisy. How do cells achieve precise timing with noisy…

Molecular Networks · Quantitative Biology 2018-07-04 Shivam Gupta , Julien Varennes , Hendrik C. Korswagen , Andrew Mugler

With the rapid development of information nowadays, spectrum resources are becoming more and more scarce, leading to a shift in the research direction from the modulation classification of a single signal to the modulation classification of…

Signal Processing · Electrical Eng. & Systems 2022-05-23 Jiahao Xu , Zihuai Lin

Neural decoding may be formulated as dynamic state estimation (filtering) based on point process observations, a generally intractable problem. Numerical sampling techniques are often practically useful for the decoding of real neural data.…

Neurons and Cognition · Quantitative Biology 2019-01-15 Yuval Harel , Ron Meir , Manfred Opper

Automatic modulation classification (AMC) is of crucial importance for realizing wireless intelligence communications. Many deep learning based models especially convolution neural networks (CNNs) have been proposed for AMC. However, the…

Signal Processing · Electrical Eng. & Systems 2021-08-24 Hao Zhang , Lu Yuan , Guangyu Wu , Fuhui Zhou , Qihui Wu

Recurrently connected neuron populations play key roles in sensory perception and memory storage across various brain regions. While these populations are often assumed to encode information through firing rates, this method becomes…

Neurons and Cognition · Quantitative Biology 2025-09-05 Mauricio Girardi-Schappo , Leonard Maler , André Longtin

The theta rhythm is important for many cognitive functions including spatial processing, memory encoding, and memory recall. The information processing underlying these functions is thought to rely on consistent, phase-specific spiking…

Neurons and Cognition · Quantitative Biology 2025-10-16 Oleg Makarenkov , Marianne Bezaire , Michael Hasselmo

We typically think of cells as responding to external signals independently by regulating their gene expression levels, yet they often locally exchange information and coordinate. Can such spatial coupling be of benefit for conveying…

Molecular Networks · Quantitative Biology 2015-01-19 Thomas R. Sokolowski , Gašper Tkačik

In this paper, a novel time-based modulation scheme is proposed in the time-asynchronous channel for diffusion-based molecular communication systems with drift. Based on this modulation scheme, we demonstrate that the sample variance of…

Information Theory · Computer Science 2019-05-31 Qingchao Li

Neuronal spiking exhibits an exquisite combination of modulation and robustness properties, rarely matched in artificial systems. We exploit the particular interconnection structure of conductance based models to investigate this remarkable…

Neurons and Cognition · Quantitative Biology 2013-11-12 Guillaume Drion , Alessio Franci , Vincent Seutin , Rodolphe Sepulchre

Intelligent spectrum management is crucial for improving spectrum efficiency and achieving secure utilization of spectrum resources. However, existing intelligent spectrum management methods, typically based on small-scale models, suffer…

Signal Processing · Electrical Eng. & Systems 2025-12-16 Fuhui Zhou , Chunyu Liu , Hao Zhang , Wei Wu , Qihui Wu , Tony Q. S. Quek , Chan-Byoung Chae

Automatic modulation classification is a desired feature in many modern software-defined radios. In recent years, a number of convolutional deep learning architectures have been proposed for automatically classifying the modulation used on…

Machine Learning · Computer Science 2023-01-30 Clayton Harper , Mitchell Thornton , Eric Larson

Recent learning-based image classification and speech recognition approaches make extensive use of attention mechanisms to achieve state-of-the-art recognition power, which demonstrates the effectiveness of attention mechanisms. Motivated…

Signal Processing · Electrical Eng. & Systems 2022-01-12 Shangao Lin , Yuan Zeng , Yi Gong

The development of new techniques to quantitatively measure gene expression in cells has shed light on a number of systems that display oscillations in protein concentration. Here we review the different mechanisms which can produce…

Molecular Networks · Quantitative Biology 2009-11-13 G. Tiana , S. Krishna , S. Pigolotti , M. H. Jensen , K. Sneppen

Molecular signalling in living cells occurs at low copy numbers and is thereby inherently limited by the noise imposed by thermal diffusion. The precision at which biochemical receptors can count signalling molecules is intimately related…

Statistical Mechanics · Physics 2016-09-26 Aljaz Godec , Ralf Metzler

Both action potentials and mechanosensitive signalling are an important communication mechanisms in plants. Considering an information theoretic framework, this paper explores the effective range of multiple action potentials for a long…

Molecular Networks · Quantitative Biology 2019-11-13 Hamdan Awan , Kareem Zeid , Raviraj S. Adve , Nigel Wallbridge , Carrol Plummer , Andrew W. Eckford

Fast radio bursts (FRBs) are intense, short-duration radio transients of mysterious origin. They have been detected across a wide range of frequencies from 110 MHz to 8 GHz. Their spectral properties, remaining poorly understood, are…

High Energy Astrophysical Phenomena · Physics 2026-05-13 Rui-Nan Li , Hao-Tian Lan , Zhen-Yin Zhao , Qin Wu , Fa-Yin Wang , Zi-Gao Dai

The living cell expends energetic and material resources to reliably process information from its environment. To do so, it utilises unreliable molecular circuitry that is subject to thermal and other fluctuations. Here, we argue that…

Soft Condensed Matter · Physics 2022-04-12 Kabir Husain , Sriram Ramaswamy , Madan Rao

Understanding how the complex connectivity structure of the brain shapes its information-processing capabilities is a long-standing question. By focusing on a paradigmatic architecture, we study how the neural activity of excitatory and…

Statistical Mechanics · Physics 2024-10-18 Giacomo Barzon , Daniel Maria Busiello , Giorgio Nicoletti