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Conventional sampling focuses on encoding and decoding bandlimited signals by recording signal amplitudes at known time points. Alternately, sampling can be approached using biologically-inspired schemes. Among these are integrate-and-fire…

Signal Processing · Electrical Eng. & Systems 2020-02-17 Karen Adam , Adam Scholefield , Martin Vetterli

This survey paper focuses on modulation aspects of molecular communication, an emerging field focused on building biologically-inspired systems that embed data within chemical signals. The primary challenges in designing these systems are…

Emerging Technologies · Computer Science 2020-12-29 Mehmet Sukru Kuran , H. Birkan Yilmaz , Ilker Demirkol , Nariman Farsad , Andrea Goldsmith

In this paper we show that living cells can multiplex biochemical signals, i.e. transmit multiple signals through the same signaling pathway simultaneously, and yet respond to them very specifically. We demonstrate how two binary input…

Molecular Networks · Quantitative Biology 2012-06-01 Wiet de Ronde , Filipe Tostevin , Pieter Rein ten Wolde

Modulation classification is an essential step of signal processing and has been regularly applied in the field of tele-communication. Since variations of frequency with respect to time remains a vital distinction among radio signals having…

Signal Processing · Electrical Eng. & Systems 2023-06-09 Muhammad Waqas , Muhammad Ashraf , Muhammad Zakwan

Neurons encode and transmit information in spike sequences. However, despite the effort devoted to quantify their information content, little progress has been made in this regard. Here we use a nonlinear method of time-series analysis…

Neurons and Cognition · Quantitative Biology 2020-02-19 Cristian Estarellas , Maria Masoliver , Cristina Masoller , Claudio Mirasso

Automatic modulation classification (AMC) is a crucial stage in the spectrum management, signal monitoring, and control of wireless communication systems. The accurate classification of the modulation format plays a vital role in the…

Signal Processing · Electrical Eng. & Systems 2023-04-04 Jiawei Zhang , Tiantian Wang , Zhixi Feng , Shuyuan Yang

Frequency offset modulation (FOM) is proposed as a new concept to provide both high energy efficiency and high spectral efficiency for communications. In the FOM system, an array of transmitters (TXs) is deployed and only one TX is…

Information Theory · Computer Science 2016-12-22 Xihua Zou , Wei Pan , Ge Yu , Bin Luo , Lianshan Yan

Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the extent to which the precise timing of these spikes is relevant…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ilya Nemenman , Geoffrey D. Lewen , William Bialek , Rob R. de Ruyter van Steveninck

It often is emphasized that gene expression is noisy. A seemingly contradictory view is that control mechanisms have been optimized to squeeze as much information as possible out of a limited number of molecules. Here we revisit these…

Biological Physics · Physics 2025-12-17 Nicholas Lawson , William Bialek

Inter and intra-cellular signaling are essential for individual cells to execute various physiological tasks and accurately respond to changes in their environment. Signaling is carried out via diffusible molecules, the transport of which…

Soft Condensed Matter · Physics 2020-10-13 Sumantra Sarkar , Sandeep Choubey

Adaptive modulation and coding (AMC) is widely employed in modern wireless communication systems to improve the transmission efficiency by adjusting the transmission rate according to the channel conditions. Thus, AMC can provide very…

Signal Processing · Electrical Eng. & Systems 2017-12-21 Zhe Yang , Lin Cai , Aaron Gulliver , Liang He , Jianping Pan

Differential modulation schemes are very relevant in receivers having power and processing limitations, as these schemes dispense with the need for knowledge of channel coefficients for symbol detection. Spatial modulation (SM) is a scheme…

Signal Processing · Electrical Eng. & Systems 2024-10-28 Deepak Jose , Sameer S. M

Why do biological and artificial neurons sometimes modularise, each encoding a single meaningful variable, and sometimes entangle their representation of many variables? In this work, we develop a theory of when biologically inspired…

Neurons and Cognition · Quantitative Biology 2025-08-05 Will Dorrell , Kyle Hsu , Luke Hollingsworth , Jin Hwa Lee , Jiajun Wu , Chelsea Finn , Peter E Latham , Tim EJ Behrens , James CR Whittington

Numerous biological functions-such as enzymatic catalysis, the immune response system, and the DNA-protein regulatory network-rely on the ability of molecules to specifically recognize target molecules within a large pool of similar…

Molecular Networks · Quantitative Biology 2010-07-27 Yonatan Savir , Tsvi Tlusty

In a molecular communication network, transmitters may encode information in concentration or frequency of signalling molecules. When the signalling molecules reach the receivers, they react, via a set of chemical reactions or a molecular…

Molecular Networks · Quantitative Biology 2020-07-23 Chun Tung Chou

Across diverse biological systems -- ranging from neural networks to intracellular signaling and genetic regulatory networks -- the information about changes in the environment is frequently encoded in the full temporal dynamics of the…

Quantitative Methods · Quantitative Biology 2020-07-01 Sarah A Cepeda-Humerez , Jakob Ruess , Gašper Tkačik

Molecular Communications (MC) is a bio-inspired communication technique that uses molecules to transfer information among bio-nano devices. In this paper, we focus on the detection problem for biological MC receivers employing ligand…

Emerging Technologies · Computer Science 2021-05-13 Murat Kuscu , Ozgur B. Akan

We study diversity in one-shot communication over molecular timing channels. We consider a channel model where the transmitter simultaneously releases a large number of information particles, while the information is encoded in the time of…

Information Theory · Computer Science 2018-01-18 Yonathan Murin , Nariman Farsad , Mainak Chowdhury , Andrea Goldsmith

Several studies have shown that bursting neurons can encode information in the number of spikes per burst: As the stimulus varies, so does the length of individual bursts. The represented stimuli, however, vary substantially among different…

Neurons and Cognition · Quantitative Biology 2013-03-22 Inés Samengo , Germán Mato , Daniel H. Elijah , Susanne Schreiber , Marcelo A. Montemurro

We describe a simple conductance-based model neuron that includes intra- and extra-cellular ion concentration dynamics and show that this model exhibits periodic bursting. The bursting arises as the fast spiking behavior of the neuron is…

Cell Behavior · Quantitative Biology 2011-09-22 Ernest Barreto , John R. Cressman